Nicotinic acid: nutrient, cofactor, drug
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
New York u.a.
Dekker
1983
|
| Series: | Clinical pharmacology
1 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | X, 308 S. |
| ISBN: | 0824770153 |
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| 650 | 4 | |a Niacin |x Metabolism | |
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Record in the Search Index
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| adam_text | - SOS 3 NIOOTINIC ACID NUTRIENT-COFACTOR-DRUG MURRAY WEINER UNIVERSITY
OF CINCINNATI COLLEGE OF MEDICINE CINCINNATI, OHIO JAN VAN EYS
UNIVERSITY OF TEXAS SYSTEM CANCER CENTER M.D. ANDERSON HOSPITAL AND
TUMOR INSTITUTE HOUSTON, TEXAS UNIVERSITATS- BIBLIOTHEK MARCEL DEKKER,
INC. NEW YORK AND BASEL CONTENTS PREFACE III INTRODUCTION VIII PART I:
NICOTINIC ACID AS A NUTRIENT 1 1. THE DISCOVERY OF NICOTINIC ACID AS A
NUTRIENT 3 I. NOMENCLATURE II. NUTRITIONAL HISTORY REFERENCES 2.
NUTRITIONAL BIOCHEMISTRY 17 I. INTRODUCTION II. THE INTERRELATIONSHIPS
BETWEEN TRYPTOPHAN AND NICOTINIC ACID REFERENCES 3. NICOTINIC ACID
BIOSYNTHESIS IN PLANTS AND MICROORGANISMS 39 I. NICOTINIC ACID
BIOSYNTHESIS IN FUNGI II. NICOTINIC ACID BIOSYNTHESIS IN BACTERIA III.
NICOTINIC ACID BIOSYNTHESIS IN PROTOZOA IV. NICOTINIC ACID BIOSYNTHESIS
IN PLANTS REFERENCES 4. NICOTINIC ACID METABOLISM AND EXCRETION 43 I.
NICOTINIC ACID EXCRETION AFTER PHARMACOLOGICAL DOSES II. METABOLISM OF
PHYSIOLOGICAL AMOUNTS OF NICOTINIC ACID III. NORMAL EXCRETION OF
NICOTINIC ACID METABOLITES IN HUMANS REFERENCES IV CONTENTS 5.
ASSESSMENT OF THE ADEQUACY OF NIACIN NUTRITURE 51 I. AVAILABLE
METHODOLOGIES II. PRACTICAL NUTRITIONAL ASSESSMENT REFERENCES 6.
NICOTINIC ACID NUTRITURE 73 I. TRYPTOPHAN REQUIREMENTS II. THE
REQUIREMENTS FOR TRYPTOPHAN PLUS NIACIN III. AMINO ACID IMBALANCE AND
NIACIN NUTRITURE IV. DIETARY DISTRIBUTION V. ALTERNATIVE SOURCES OF
NICOTINIC ACID ACTIVITY REFERENCES 7. NICOTINIC ACID ANTAGONISTS 109 I.
NICOTINIC ACID ANTAGONISTS FOR BACTERIAL GROWTH II. NICOTINIC ACID
ANTAGONISTS IN ANIMALS III. CONCLUSIONS REFERENCES PART II: NICOTINIC
ACID AS A COFACTOR 131 8. THE HISTORY OF NICOTINIC ACID AS A COENZYME
133 I. THE DISCOVERY OF COEN ZYMES I AND II II. OTHER NATURALLY
OCCURRING NICOTINAMIDE NUCLEOTIDES III. STRUCTURAL DETERMINATION OF
NICOTINAMIDE COEN ZYMES IV. THE NOMENCLATURE OF NICOTINAMIDE COEN ZYMES
V. THE STRUCTURE OF REDUCED NICOTINAMIDE COEN ZYMES VI. THE TERTIARY
STRUCTURE OF NICOTINAMIDE COEN ZYMES REFERENCES 9. THE BIOORGANIC
CHEMISTRY OF NICOTINAMIDE COEN ZYMES 145 I. THE MECHANISM OF CHEMICAL
REDUCTION II. THE CHEMICAL PROPERTIES OF NAD(P) AND NAD(P)H III. THE
CHEMISTRY OF REDUCED N 1 -SUBSTITUTED NICOTINAMIDES AND ANALOGUES IV.
ONE-OR TWO-ELECTRON REDUCTION OF PYRIDINE NUCLEOTIDES V.
STEREOSPECIFICITY OF THE COENZYMATIC REDUCTION REFERENCES 10. THE
BIOSYNTHESIS OF NICOTINAMIDE COENZYMES 155 I. BIOSYNTHETIC PATHWAYS OF
PYRIDINE NUCLEOTIDES II. THE BIOSYNTHESIS OF NADP III. NAD DEGRADATION
VI CONTENTS IV. CELLULAR LOCALIZATION OF NAD BIOSYNTHESIS AND
DEGRADATION V. REGULATION OF NAD BIOSYNTHESIS REFERENCES 11.
NICOTINAMIDE COENZYME ANALOGUES 169 I. SYNTHESIS OF COENZYME ANALOGUES
II. FUNCTIONAL CAPACITY OF COENZYME ANALOGUES REFERENCES 12.
OXIDATION*REDUCTION FUNCTIONS OF NICOTINAMIDE COENZYMES 173 I. TYPES OF
OXIDOREDUCTION FUNCTIONS OF NICOTINAMIDE COEN ZYMES II. NOMENCLATURE OF
PYRIDINE NUCLEOTIDE-DEPENDENT DEHYDROGENASES III. PROPERTIES OF
DEHYDROGENASES IV. GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE V.
CONCLUDING REMARKS REFERENCES 13. NICOTINAMIDE-ADENINE-DINUCLEOTIDES AS
HIGH-ENERGY DONORS FOR TRANSRIBOSYLATION REACTIONS 193 I.
MONO-ADP-RIBOSYLATION AS EXEMPLIFIED BY DIPHTHERIA TOXIN II.
POLY-ADP-RIBOSE SYNTHESIS III. FUNCTION OF POLY-ADP-RIBOSE IV. THE
EFFECT OF NICOTINAMIDE ON CELL GROWTH AND DNA METABOLISM REFERENCES 14.
CELLULAR BIOCHEMISTRY OF NICOTINAMIDE COENZYMES 209 I. THE DIVERSE
FUNCTIONS OF NAD AND NADP II. THE COMPARTMENTATION OF PYRIDINE
NUCLEOTIDES III. TRANSHYDROGENATION REACTIONS IV. OXIDATIVE
PHOSPHORYLATION AND THE POSSIBLE ROLE OF PYRIDINE NUCLEOTIDE
TRANSHYDROGENASE REFERENCES 15. CONCLUDING REMARKS 225 PART III:
NICOTINIC ACID AS A DRUG 227 16. PHARMACOKINETICS 229 I. ANALYTICAL
METHODS II. ABSORPTION III. DISTRIBUTION CONTENTS VII IV. METABOLISM V.
EXCRETION REFERENCES 17. PHARMACODYNAMICS 243 I. INHIBITION OF NAD
SYNTHESIS II. EFFECT ON CYCLIC AMP III. EFFECT ON PROSTAGLANDIN ACTION
IV. EFFECT ON NEUROHUMORAL TRANSMITTER ACTION V. OTHER MECHANISMS OF
ACTION REFERENCES 18. TREATMENT OF THE HYPERLIPIDEMIAS 253 I. BLOOD
LIPIDS AND ATHEROSCLEROSIS II. PATTERNS OF HYPERLIPIDEMIA III. DIETARY
CONTROL OF LIPID PATTERNS IV. DRUG THERAPY FOR HYPERLIPIDEMIA V.
NICOTINIC ACID FOR HYPERLIPIDEMIA VI. OTHER CONSEQUENCES OF DRUG
TREATMENT OF HYPERLIPIDEMIA REFERENCES 19. NICOTINIC ACID EFFECTS ON
VASCULAR TONE 273 I. MEASUREMENT OF VASOMOTOR RESPONSES II. VASCULAR
RESPONSE TO NICOTINIC ACID III. CLINICAL UTILITY OF THE VASCULAR
RESPONSE TO NICOTINIC ACID REFERENCES 20. INDUCTION OF FIBRINOLYSIS BY
NICOTINIC ACID 281 I. NICOTINIC ACID-INDUCED FIBRINOLYSIS II. RELATION
TO HEPATIC DISEASE ;; III. MECHANISMS AND CLINICAL CONSEQUENCES
REFERENCES 21. MISCELLANEOUS PHARMACOLOGICAL AND CLINICAL ACTIONS 293 I.
NICOTINIC ACID IN MENTAL DISEASE II. EFFECT ON INTESTINAL SECRETIONS
III. INTERACTION WITH CARCINOGENS IV. ANTINIACIN (PELLAGRAGENIC) DRUGS
V. NIACIN-LIKE DRUG ACTIONS REFERENCES SUBJECT INDEX 301
|
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| id | DE-604.BV000151379 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-09T15:09:27Z |
| institution | BVB |
| isbn | 0824770153 |
| language | English |
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| physical | X, 308 S. |
| publishDate | 1983 |
| publishDateSearch | 1983 |
| publishDateSort | 1983 |
| publisher | Dekker |
| record_format | marc |
| series | Clinical pharmacology |
| series2 | Clinical pharmacology |
| spelling | Weiner, Murray Verfasser aut Nicotinic acid nutrient, cofactor, drug Murray Weiner ; Jan Van Eys New York u.a. Dekker 1983 X, 308 S. txt rdacontent n rdamedia nc rdacarrier Clinical pharmacology 1 Nicotinique, Acide - Effets physiologiques Nicotinique, Acide - Emploi en thérapeutique Nicotinique, Acide - Métabolisme Niacin Metabolism Niacin Physiological effect Niacin Therapeutic use Nicotinic Acids Nicotinsäure (DE-588)4171834-3 gnd rswk-swf Nicotinsäure (DE-588)4171834-3 s DE-604 Van Eys, Jan Verfasser aut Clinical pharmacology 1 (DE-604)BV000010647 1 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000084863&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Weiner, Murray Van Eys, Jan Nicotinic acid nutrient, cofactor, drug Clinical pharmacology Nicotinique, Acide - Effets physiologiques Nicotinique, Acide - Emploi en thérapeutique Nicotinique, Acide - Métabolisme Niacin Metabolism Niacin Physiological effect Niacin Therapeutic use Nicotinic Acids Nicotinsäure (DE-588)4171834-3 gnd |
| subject_GND | (DE-588)4171834-3 |
| title | Nicotinic acid nutrient, cofactor, drug |
| title_auth | Nicotinic acid nutrient, cofactor, drug |
| title_exact_search | Nicotinic acid nutrient, cofactor, drug |
| title_full | Nicotinic acid nutrient, cofactor, drug Murray Weiner ; Jan Van Eys |
| title_fullStr | Nicotinic acid nutrient, cofactor, drug Murray Weiner ; Jan Van Eys |
| title_full_unstemmed | Nicotinic acid nutrient, cofactor, drug Murray Weiner ; Jan Van Eys |
| title_short | Nicotinic acid |
| title_sort | nicotinic acid nutrient cofactor drug |
| title_sub | nutrient, cofactor, drug |
| topic | Nicotinique, Acide - Effets physiologiques Nicotinique, Acide - Emploi en thérapeutique Nicotinique, Acide - Métabolisme Niacin Metabolism Niacin Physiological effect Niacin Therapeutic use Nicotinic Acids Nicotinsäure (DE-588)4171834-3 gnd |
| topic_facet | Nicotinique, Acide - Effets physiologiques Nicotinique, Acide - Emploi en thérapeutique Nicotinique, Acide - Métabolisme Niacin Metabolism Niacin Physiological effect Niacin Therapeutic use Nicotinic Acids Nicotinsäure |
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| volume_link | (DE-604)BV000010647 |
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