Ether lipids: biochemical and biomedical aspects
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Acad. Press
1983
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVII, 439 S. |
| ISBN: | 0124687806 |
Internformat
MARC
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| 245 | 1 | 0 | |a Ether lipids |b biochemical and biomedical aspects |c ed. by H. K. Mangold ... |
| 264 | 1 | |a New York [u.a.] |b Acad. Press |c 1983 | |
| 300 | |a XVII, 439 S. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 4 | |a Lipides | |
| 650 | 4 | |a Lipides - Effets physiologiques | |
| 650 | 4 | |a Éthers | |
| 650 | 4 | |a Éthers - Effets physiologiques | |
| 650 | 4 | |a Ether lipids |x Physiological effect | |
| 650 | 4 | |a Ethers | |
| 650 | 4 | |a Lipids | |
| 650 | 4 | |a Lipids |x physiology | |
| 650 | 0 | 7 | |a Ether-Lipide |0 (DE-588)4124866-1 |2 gnd |9 rswk-swf |
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| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Mangold, Helmut K. |e Sonstige |4 oth | |
| 856 | 4 | 2 | |m Digitalisierung UB Regensburg |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000056676&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-000056676 | ||
Datensatz im Suchindex
| _version_ | 1804114565562105856 |
|---|---|
| adam_text | CONTENTS
Contributors
xi
Preface
xiii
Terminology and Abbreviations
1. Chromatographie
Analysis, Isolation, and Characterization
of Ether Lipids
Tore Curstedt
I. Introduction
1
II. Extraction and Purification of Lipids
2
III. Analysis of Ether Lipids
3
IV. Summary and Conclusions
13
References
13
2.
Mass Spectrometry of Ether Lipids
Heinz
Egge
I. Introduction
17
II. Mass Spectrometry of Alkylglycerolipids
18
III. Mass Spectrometry of l-O-U -AlkenyOglycerolipids
41
References
45
3.
Chemical Synthesis of Ether Lipids
Fritz Paltauf
I. Introduction
49
II. Alkylglycerolipids
50
vj CONTENTS
III.
l-O-ü -AlkenyOglycerolipids
71
IV.
Alkyl Lipids
Not Containing Glycerol
79
V.
ľ-Alkenyl
Lipids
Not Containing
Glycerol
80
References
80
4.
Biosynthesis of
O-Alkylglycerol Ether Lipids
Amiya K.
Hajra
I. Introduction
85
П.
Biosynthesis of Glycerol Ether Lipids from
Triose
Phosphates
86
III. Biosynthesis of Alkyl-DHAP from Acyl-DHAP
91
IV. Biosynthesis of Acyl-DHAP
92
V. Properties of Alkyl-DHAP Synthase
92
VI. Enzymatic Reduction of Alkyl-DHAP
%
VII.
Enzymatic Acylation of
і-Аікуі-лл-С-З-Р
to
і-Аїкуі-г-асуі-їп-О-З-Р
97
Vlil.
Conversion of
l-Alkyl-2
-асуі-С-З-Р
to Different Alkylglycerol Ether Lipids
98
IX. Conclusion
98
References
103
5.
Biosynthesis of
1-0-0
AlkenyOglycerolipids
(Plasmalogens)
Fritz Paltauf
I. Introduction
107
II. Biosynthesis of
Plasmalogens
in Aerobic Organisms
108
III. Biosynthesis of
Plasmalogens
in Strictly Anaerobic Microorganisms
124
References
126
6.
Substrate Specificity of Enzymes Catalyzing the Biosynthesis
of Ether Lipids
Irene Reichwald-Hacker
I. Introduction
129
II. Formation of Long-Chain Alcohols
130
III. Formation of the Ether Bond
132
IV. Enzymatic Acylation of Alkylglycerolipids
134
V. Ethanolaminephosphotransferase and Cholinephosphotransferase
135
VI. Dehydrogenation of Alkylglycerolipids to
Plasmalogens
136
Vil.
Conclusion
138
References
139
Contents
vii
7.
Ether Glycolipids
Heinz
Egge
I. Introduction
141
II. Bacterial Ether Glycolipids
142
III. Mammalian Ether Glycolipids
145
IV. Conclusion
156
References
156
Dialkyldiglycerol Tetraethers
Thomas A. Langworthy
1.
Introduction
161
II. Occurrence
162
III. Chemistry of Dialkyldiglycerol Tetraethers
163
IV. Conclusion
172
References
174
9.
Ether Lipids Containing Steryl Moieties
Fritz Paltauf
I. Occurrence
177
II. Chemical Synthesis
178
III. Application in Biochemical Studies
180
References
183
10.
Divinyl Ether Fatty Acids
Terence Galiiard
I. Introduction
185
II. Occurrence
186
III. Isolation and Purification
187
IV. Structure Elucidation
187
V. Biosynthesis
189
VI. Degradation
191
VII.
Function of Vinyl Ether Fatty Acids
193
References
194
CONThNTS
11.
Autoxidation
of Ether Lipids
Nedjalka VI. Yanishlieva-Maslarova
I. Introduction
195
II. Autoxidation Kinetics
196
III. Autoxidation Products and the Mechanism of Their Formation
204
IV. Conclusions
208
References
209
12.
Ether Lipids as Substrates for Lipolytic Enzymes
Fritz Pahauf
I. Introduction
211
II. Lipolytic Enzymes Involved in the Catabolism of Ether Lipids
212
III. Ether Lipids as Model Compounds in Studies on Lipolytic Processes
216
IV. Application of Lipolytic Enzymes for the Preparation of Ether Lipids
224
V. Application of Diether Phospholipids in the Preparation and Affinity
Labeling of Phospholipase
ΑΊ
226
References
227
13.
Ether Lipids in the Diet of Humans and Animals
Helmut K. Mangold
I. Introduction
231
II. Ether Lipids in Human Food and Animal Feed
232
III. Metabolism of Ether Lipids in the Alimentary Canal
234
IV. Ether Lipids as Nonfattening Fats
236
V. Prospectus
236
References
237
14.
Ether Lipids in Clinical Diagnosis and Medical Research
Friedrich Spener
I. Introduction
239
II. Trialkylglycerols (Triethers) in Fat Absorption Studies
240
HI. Ether Lipids as Chemical Indicators in Neoplasms
248
IV. Ether Lipids as Chemical Mediators
252
V. Conclusions
256
References
257
Contents
ix
15.
Therapeutic Effects of Ether Lipids
Bo Hallgren
I. Introduction
261
II. Alkylglycerols and Their Esters
262
III. Methoxy-Substituted Alkylglycerols
268
IV. Acetal Analogs of Phosphatidic Acids
273
V. Alkyl
Ethers of Halogenopropanediols
274
References
274
16.
Synthetic
Alkyl
Analogs of Lysophosphatidylcholine: Membrane Activity,
Metabolic Stability, and Effects on Immune Response and Tumor Growth
Hans U. Weltzien and Paul G.
Münder
I. Introduction
277
II. Interactions of LLAs with Cell Surfaces
280
III. Effect of LLAs on Immune Response
286
IV. Effects of LLAs on the Growth of Experimental Tumors
290
V. Metabolic Stability of LLAs
299
VI. Conclusions
301
References
306
17.
Ether Lipids in Biological and Model Membranes
Fritz Paltauf
I. Introduction
309
II. Ether Lipids in Biological Membranes
311
III. Ether Lipids in Model Membranes
323
References
349
18.
Platelet-Activating Factor: An Ether
Lipid
with Biological Activity
Jacques Benveniste and Bernardo B. Vargaftig
1.
Introduction
356
II. Historical Background and Definition
356
HI. Cellular Origin of PAF-Acether
358
IV. Interactions of PAF-Acether with Platelets
362
V. Molecular Assembly of PAF-Acether
365
Contents
VI. Biological Activities of PAF-Acether Analogs: Structure-Activity
Relationships
366
VII. PAF-Acether
in Physiology and Pathology
367
VIII.
Other Effects of PAF-Acether
369
IX. The End Result of Leukocyte-Platelet Interaction: Enhancement of Vascular
Permeability-Its Role in Physiology and Pathology
371
X. Conclusions
372
References
373
19.
Procedures for the Analysis of Ether Lipids
Helmut K. Mangold and Nagao
Totani
I. General Methods
377
11.
Specific Procedures
378
References
387
20.
Procedures for the Synthesis of Ether Lipids
Albin Hermetter
and Fritz Paltauf
I. General Methods
390
II. Procedures
390
References
419
21.
Procedures for
Biomedical
Investigations
Fritz Paltauf and
Beate
M.
Czarnetzki
I. Preparation of Small Unilamellar Vesicles
421
11.
Preparation of Large Unilamellar Vesicles
422
III. Assay of the Stereospecificity of Triacylglycerol Hydrolases
423
IV. Assay of the Effect of Lipids on Neutrophil Migration
424
V. Assay of l-O-AlkyW-O-acetyl-sn-glycero-S-phosphocholines (Platelet-Activating
Factor) with
Radiolabeled
Serotonin
425
References
426
Index
429
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| spelling | Ether lipids biochemical and biomedical aspects ed. by H. K. Mangold ... New York [u.a.] Acad. Press 1983 XVII, 439 S. txt rdacontent n rdamedia nc rdacarrier Lipides Lipides - Effets physiologiques Éthers Éthers - Effets physiologiques Ether lipids Physiological effect Ethers Lipids Lipids physiology Ether-Lipide (DE-588)4124866-1 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Ether-Lipide (DE-588)4124866-1 s DE-604 Mangold, Helmut K. Sonstige oth Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000056676&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Ether lipids biochemical and biomedical aspects Lipides Lipides - Effets physiologiques Éthers Éthers - Effets physiologiques Ether lipids Physiological effect Ethers Lipids Lipids physiology Ether-Lipide (DE-588)4124866-1 gnd |
| subject_GND | (DE-588)4124866-1 (DE-588)4143413-4 |
| title | Ether lipids biochemical and biomedical aspects |
| title_auth | Ether lipids biochemical and biomedical aspects |
| title_exact_search | Ether lipids biochemical and biomedical aspects |
| title_full | Ether lipids biochemical and biomedical aspects ed. by H. K. Mangold ... |
| title_fullStr | Ether lipids biochemical and biomedical aspects ed. by H. K. Mangold ... |
| title_full_unstemmed | Ether lipids biochemical and biomedical aspects ed. by H. K. Mangold ... |
| title_short | Ether lipids |
| title_sort | ether lipids biochemical and biomedical aspects |
| title_sub | biochemical and biomedical aspects |
| topic | Lipides Lipides - Effets physiologiques Éthers Éthers - Effets physiologiques Ether lipids Physiological effect Ethers Lipids Lipids physiology Ether-Lipide (DE-588)4124866-1 gnd |
| topic_facet | Lipides Lipides - Effets physiologiques Éthers Éthers - Effets physiologiques Ether lipids Physiological effect Ethers Lipids Lipids physiology Ether-Lipide Aufsatzsammlung |
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