On paraenzymatic functions of heme oxygenase-1:
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 40 Bl. in getr. Zählung Ill., graph. Darst. 30 cm |
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Datensatz im Suchindex
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| adam_text | Titel: On paraenzymatic functions of heme oxygenase-1
Autor: Weis, Sebastian
Jahr: 2008
1. Introduction 1
l.l.HO-1 1
1.2. HO reaction byproducts 3
1.3. HO-1 gene 4
1.3.1. Organization of the HO-1 gene 4
1.3.2. Human gene polymorphism 5
1.4. Regulation of HO-1 expression 5
1.5. HO isoenzymes 6
1.6. Aim of the study 7
2. Results 8
2.1. Interaction of HO-1 and HO-2 isoenzymes 8
2.2. Nuclear localization of HO-1 10
2.2.1. Nuclear translocation upon hypoxia, hemin and hemopexin 10
2.2.2. C-terminal cleavage and nuclear translocation 11
2.2.3. Nuclear shuttling sequence (NSS) 12
2.3. Nonenzymatic actions of HO-1 14
2.3.1. HO-1 delivery 14
2.3.2. Promoter activation by HO-1 protein 15
2.3.3. Activation of different transcription factors 17
2.3.4. Enhanced TF binding after HO-1 delivery 19
3. Summary 21
4. Abbreviation List i
5. Acknowledgements iii
6. Annex iv
7. References v
8. Erklarung uber die eigenstandige Abfassung der Arbeit xii
9. Curriculum Vitae xiii
A
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| adam_txt |
Titel: On paraenzymatic functions of heme oxygenase-1
Autor: Weis, Sebastian
Jahr: 2008
1. Introduction 1
l.l.HO-1 1
1.2. HO reaction byproducts 3
1.3. HO-1 gene 4
1.3.1. Organization of the HO-1 gene 4
1.3.2. Human gene polymorphism 5
1.4. Regulation of HO-1 expression 5
1.5. HO isoenzymes 6
1.6. Aim of the study 7
2. Results 8
2.1. Interaction of HO-1 and HO-2 isoenzymes 8
2.2. Nuclear localization of HO-1 10
2.2.1. Nuclear translocation upon hypoxia, hemin and hemopexin 10
2.2.2. C-terminal cleavage and nuclear translocation 11
2.2.3. Nuclear shuttling sequence (NSS) 12
2.3. Nonenzymatic actions of HO-1 14
2.3.1. HO-1 delivery 14
2.3.2. Promoter activation by HO-1 protein 15
2.3.3. Activation of different transcription factors 17
2.3.4. Enhanced TF binding after HO-1 delivery 19
3. Summary 21
4. Abbreviation List i
5. Acknowledgements iii
6. Annex iv
7. References v
8. Erklarung uber die eigenstandige Abfassung der Arbeit xii
9. Curriculum Vitae xiii
A |
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| ctrlnum | (OCoLC)260079951 (DE-599)DNB990262677 |
| dewey-full | 612.01 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
| dewey-raw | 612.01 |
| dewey-search | 612.01 |
| dewey-sort | 3612.01 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| discipline_str_mv | Medizin |
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| spelling | Weis, Sebastian 1978- Verfasser (DE-588)136179428 aut On paraenzymatic functions of heme oxygenase-1 eingereicht von: Sebastian Weis 2008 40 Bl. in getr. Zählung Ill., graph. Darst. 30 cm txt rdacontent n rdamedia nc rdacarrier Leipzig, Univ., Diss., 2008 (DE-588)4113937-9 Hochschulschrift gnd-content HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016995330&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Weis, Sebastian 1978- On paraenzymatic functions of heme oxygenase-1 |
| subject_GND | (DE-588)4113937-9 |
| title | On paraenzymatic functions of heme oxygenase-1 |
| title_auth | On paraenzymatic functions of heme oxygenase-1 |
| title_exact_search | On paraenzymatic functions of heme oxygenase-1 |
| title_exact_search_txtP | On paraenzymatic functions of heme oxygenase-1 |
| title_full | On paraenzymatic functions of heme oxygenase-1 eingereicht von: Sebastian Weis |
| title_fullStr | On paraenzymatic functions of heme oxygenase-1 eingereicht von: Sebastian Weis |
| title_full_unstemmed | On paraenzymatic functions of heme oxygenase-1 eingereicht von: Sebastian Weis |
| title_short | On paraenzymatic functions of heme oxygenase-1 |
| title_sort | on paraenzymatic functions of heme oxygenase 1 |
| topic_facet | Hochschulschrift |
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