Molecular mechanism of Atg1 kinase and autophagy activation:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
Freiburg im Breisgau
Mai 2019
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Inhaltsverzeichnis |
| Beschreibung: | Enthält Sonderabdrucke |
| Beschreibung: | 116 Seiten Illustrationen, Diagramme 30 cm |
Internformat
MARC
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| 245 | 1 | 0 | |a Molecular mechanism of Atg1 kinase and autophagy activation |c vorgelegt von Raffaela Torggler |
| 264 | 1 | |a Freiburg im Breisgau |c Mai 2019 | |
| 300 | |a 116 Seiten |b Illustrationen, Diagramme |c 30 cm | ||
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Datensatz im Suchindex
| _version_ | 1804180609667432448 |
|---|---|
| adam_text | ABSTRACT
..............................................................................................................................
1
INTRODUCTION
........................................................................................................................
2
AUTOPHAGY
-
A
CELLULAR
WASTE
DISPOSAL
SYSTEM
..................................................................................
2
TYPES
OF
AUTOPHAGY
.................................................................................................................................
2
BULK
AND
SELECTIVE
AUTOPHAGY
IN
SACCHAROMYCES
CEREVISIAE
...............................................................
3
MOLECULAR
MECHANISMS
OF
THE
AUTOPHAGIC
MACHINERY
......................................................................
5
EARLY
STEPS
DURING
STARVATION-INDUCED
BULK
AUTOPHAGY
.........................................................................
5
EARLY
STEPS
DURING
THE
CVT
PATHWAY
........................................................................................................
8
AUTOPHAGOSOME
FORMATION
AND
FUSION
WITH
THE
VACUOLE
.......................................................................
9
AUTOPHAGY
IN
MAMMALS
AND
DISEASE
..................................................................................................
10
MOLECULAR
MACHINERY
IN
MAMMALIAN
AUTOPHAGY
..................................................................................
10
AUTOPHAGY
IN
HUMAN
DISEASE
...............................................................................................................
11
TWO
INDEPENDENT
PATHWAYS
WITHIN
SELECTIVE
AUTOPHAGY
CONVERGE
TO
ACTIVATE
ATG1
KINASE
AT
THE
VACUOLE
...........................................................................................
13
RECONSTITUTION
REVEALS
YKT6
AS
THE
AUTOPHAGOSOMAL
SNARE
IN
AUTOPHAGOSOME-VACUOLE
FUSION
.................................................................................53
ASSAYS
TO
MONITOR
AUTOPHAGY
IN
SACCHAROMYCES
CEREVISIAE
...............................70
DISCUSSION
......................................................................................................................
95
THE
SPATIOTEMPORAL
CONTROL
OF
ATG1
ACTIVATION
IN
SELECTIVE
AUTOPHAGY
........................................95
IPASS
-
A
POWERFUL
TOOL
..........................................................................................................................
96
INTERACTION
BETWEEN
ATG1
AND
ATG1
1
IS
RESTRICTED
TO
THE
VACUOLE
........................................................97
MECHANISM
OF
ATG1
ACTIVATION
IS
CONSERVED
IN
MAMMALS
...................................................................
98
MOLECULAR
MECHANISMS
OF
AUTOPHAGOSOME-VACUOLE
FUSION
...........................................................
99
EARLY
AND
LATE
STEPS
DURING
AUTOPHAGY
ARE
CONNECTED
......................................................................
100
RECONSTITUTING
AUTOPHAGOSOME-VACUOLE
FUSION
IN
VITRO
....................................................................
101
SUMMARY
AND
IMPLICATIONS
................................................................................................................
102
REFERENCES
....................................................................................................................
104
ACKNOWLEDGEMENTS
.....................................................................................................
115
PUBLICATIONS
..................................................................................................................116
|
| any_adam_object | 1 |
| author | Torggler, Raffaela |
| author_GND | (DE-588)1191215245 |
| author_facet | Torggler, Raffaela |
| author_role | aut |
| author_sort | Torggler, Raffaela |
| author_variant | r t rt |
| building | Verbundindex |
| bvnumber | BV046214143 |
| ctrlnum | (OCoLC)1125188929 (DE-599)DNB1194472753 |
| discipline | Biologie |
| format | Thesis Book |
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| indexdate | 2024-07-10T08:38:29Z |
| institution | BVB |
| language | English |
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| owner_facet | DE-355 DE-BY-UBR |
| physical | 116 Seiten Illustrationen, Diagramme 30 cm |
| publishDate | 2019 |
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| spelling | Torggler, Raffaela Verfasser (DE-588)1191215245 aut Molecular mechanism of Atg1 kinase and autophagy activation vorgelegt von Raffaela Torggler Freiburg im Breisgau Mai 2019 116 Seiten Illustrationen, Diagramme 30 cm txt rdacontent n rdamedia nc rdacarrier Enthält Sonderabdrucke Dissertation Albert-Ludwigs-Universität Freiburg 2019 (DE-588)4113937-9 Hochschulschrift gnd-content B:DE-101 application/pdf https://d-nb.info/1194472753/04 Inhaltsverzeichnis DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=031592973&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Torggler, Raffaela Molecular mechanism of Atg1 kinase and autophagy activation |
| subject_GND | (DE-588)4113937-9 |
| title | Molecular mechanism of Atg1 kinase and autophagy activation |
| title_auth | Molecular mechanism of Atg1 kinase and autophagy activation |
| title_exact_search | Molecular mechanism of Atg1 kinase and autophagy activation |
| title_full | Molecular mechanism of Atg1 kinase and autophagy activation vorgelegt von Raffaela Torggler |
| title_fullStr | Molecular mechanism of Atg1 kinase and autophagy activation vorgelegt von Raffaela Torggler |
| title_full_unstemmed | Molecular mechanism of Atg1 kinase and autophagy activation vorgelegt von Raffaela Torggler |
| title_short | Molecular mechanism of Atg1 kinase and autophagy activation |
| title_sort | molecular mechanism of atg1 kinase and autophagy activation |
| topic_facet | Hochschulschrift |
| url | https://d-nb.info/1194472753/04 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=031592973&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT torgglerraffaela molecularmechanismofatg1kinaseandautophagyactivation |
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