Hemorheology in practice:
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
IOS Press [u.a.]
1999
|
| Schriftenreihe: | Biomedical and health research
30 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | X, 128 S. graph. Darst. |
| ISBN: | 9051994354 4274902625 |
Internformat
MARC
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| 100 | 1 | |a Stolz, John F. |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Hemorheology in practice |c by J.-F. Stolz ; M.Singh ; P.Riha |
| 264 | 1 | |a Amsterdam [u.a.] |b IOS Press [u.a.] |c 1999 | |
| 300 | |a X, 128 S. |b graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Biomedical and health research |v 30 | |
| 650 | 2 | |a Hémorhéologie | |
| 650 | 7 | |a Sang - Viscosité |2 ram | |
| 650 | 4 | |a Blood Viscosity | |
| 650 | 4 | |a Blood |x Pathophysiology | |
| 650 | 4 | |a Blood |x Rheology | |
| 650 | 4 | |a Cardiovascular Diseases |x physiopathology | |
| 650 | 4 | |a Hematologic Diseases |x physiopathology | |
| 650 | 4 | |a Hemorheology | |
| 650 | 0 | 7 | |a Hämorrheologie |0 (DE-588)4123326-8 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Hämorrheologie |0 (DE-588)4123326-8 |D s |
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| 700 | 1 | |a Singh, Megha |e Verfasser |4 aut | |
| 700 | 1 | |a Riha, Pavel |e Verfasser |4 aut | |
| 830 | 0 | |a Biomedical and health research |v 30 |w (DE-604)BV009680083 |9 30 | |
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Datensatz im Suchindex
| _version_ | 1804127108374462464 |
|---|---|
| adam_text | Contents
Preface v
PART I: BLOOD RHEOLOGY AND MEASUREMENTS
Chapter 1: Introduction to Hemorheology
1.1 Hemorheology What the Word Means 1
1.2 History of Hemorheology 2
1.3 Subject of Hemorheology 4
1.4 Clinical Hemorheology 6
References 6
Chapter 2: Fundamentals of Rheology
2.1 Description of the Rheological Behaviour 9
2.1.1 Stress, Deformation and Motion 9
2.1.2 Rheological Equation 11
2.2 Hemorheology and Hemodynamics 13
References 14
Chapter 3: Blood Viscosity and Models
3.1 Variability of Blood Viscosity 15
3.1.1 Effect of Shear Stress Shear Rate Variation on Viscosity 15
3.1.2 Effect of Cell Volume Fraction on Viscosity 17
3.1.3 Effect of Shear Rate on Viscosity 17
3.1.4 Effect of Hematocrit on Blood Viscosity 18
3.1.5 Effect of Temperature on Blood Viscosity 19
3.2 Blood Flow through Glass Tubes 20
3.2.1 Fahraeus Linqvist Effect 20
3.2.2 Velocity and Erythrocyte Distribution Profiles 20
3.2.3 Viscoelastic Behaviour of Blood 21
Hysteresis of Blood Flow Behaviour 21
Oscillatory Blood Viscosity by Womersley Theory 21
Oscillatory Flow of a Linear Viscoelastic Fluid 22
References 24
Chapter 4: Microrheological Parameters
4.1 Deformability of Erythrocytes 27
4.1.1 Determinants of Erythrocyte Deformability 28
Erythrocyte Geometry 28
Internal Viscosity of Erythrocytes 28
Influence of Vessel Size 28
4.1.2 Molecular Basis of Erythrocyte Deformability 29
4.2 Aggregation of Erythrocytes 30
4.2.1 Physicochemical Mechanism of Erythrocyte Aggregation 31
viii
4.2.2 Rheological Mechanism of Erythrocyte Aggregation 33
4.2.3 Mechanism of Shear Disaggregation of Erythocytes 35
4.2.4 In Vivo Erythrocyte Aggregation 35
4.3 Rheology of Leukocytes 36
4.3.1 Morphological Characteristics 37
4.3.2 Rheological Properties of Leukocytes 37
4.3.3 Rheological Aspects of the Kinetics of Leukocyte Adhesion 38 ,
4.3.4 Rheological Aspects of Leukocyte Transmigration 40
4.3.5 Pathophysiological Implications of Leukocyte Rheology 40
4.4 Surface Charge of Blood Cells 40
4.4.1 Models of the Cell Surface Charge 40
4.4.2 Electrokinetic Phenomena 42 ?
Electroosmosis 42
Cellular Electrophoresis 43
4.5 Hemorheology of Endothelial Cells 43
4.5.1 Two Functional States of Endothelial Cells 44
Anti Thrombotic Action 44
Thrombotic and Adhesive Action 44
4.5.2 Rheological Properties 45
4.5.3 Response to Local Flow 45
4.5.4 Mechano Transduction 45
4.5.5 Adhesion Molecules 47
Selectins 47
Integrins 47
Immunoglobulin Superfamily 48
References 48 f
Chapter 5: Rheology and Blood Clotting
5.1 Hemostasis 53
5.1.1 Hemorheological Testing 54
5.1.2 Kinetics of Coagulation 56 ?
5.1.3 Diagnostics and Control of Therapy 57
5.1.4 Testing of Therapeutic Agents 5 8
5.2 Thrombosis 59
5.3 Clot Permeability and Architecture 60
References 60
Chapter 6: Measurements of Rheological Properties
6.1 Measurement of Blood and Plasma Viscosity 63
6.1.1 Rotational Viscometers 63
Cylinder Cylinder Viscometers 63
Cone Plate Viscometers 65
6.1.2 Capillary Viscometers 65
6.1.3 Oscillatory Flow Capillary Viscometer 67
6.2 Measurement of Blood Cell Deformability 67
6.2.1 Direct Observation 68
6.2.2 Light Diffusion 68
6.2.3 Suction in Micropipette 68
6.2.4 Deformation by Uniaxial Elongation 68
ix
6.2.5 Osmotic Hemolysis 68
6.2.6 Filtration Methods 69
Filtration through a Filter 69
Constant Pressure System 69
Constant Flow Rate System 70
Variable Pressure and Flow Rate System 70
Filtration through a Single Pore 70
Limitation of Filtration Methods 70
Filtration Curves and their Interpretation 71
6.3 Measurement of Erythrocyte Aggregation 72
6.3.1 Erythrocyte Sedimentation Rate 72
6.3.2 Microscopic Image Analysis 73
6.3.3 Light Transmission and Back Scattering 75
6.3.4 Ultrasonic Scattering 77
6.3.5 Centrifugation 80
6.3.6 RBC Aggregation in Oscillatory Flow 81
6.3.7 Micro Gravity Conditions 82
6.3.8 Kinetics of Aggregation 82
6.4 Electrophoresis of Blood Cells 84
6.4.1 Techniques of Cellular Electrophoresis 84
Microscopy 84
Velocity Measurement 85
Measurement of the Network Velocity 85
Doppler Velocity Measurement 85
6.4.2 Determination of the Chemical Groups on the Cell Surface 85
6.5 Spectroscopy of Blood Cell Membranes 86
6.5.1 Membrane Fluidity 87
6.5.2 Methods Using Molecular Emission Spectroscopy 88
6.5.3 Molecular Motion in Membranes 89
References 89
PART II: CLINICAL AND THERAPEUTICAL APPLICATIONS
Chapter 7: Hematological Disorders
7.1 Diseases Characterised by Increased Concentration of Blood Cells 93
7.1.1 Erythrocytosis 93
7.1.2 High Leukocyte or Platelet Counts 93
7.2 Diseases Characterised by Modification of Proteins and by Increased
Aggregation of Erythrocytes 94
7.3 Diseases Characterised by Modification in Microrheological Factors 95
7.3.1 Increased Internal Viscosity of Erythrocytes 95
Sickle Cell Diseases (HbSS) 96
Other Hemoglobinosis Disorders 97
7.3.2 Changes of Membrane Shape or Constitutional Deficiency of
the Membrane 97
Spherocytosis 97
Hemolytic Anemias 97
Secondary Membrane Disorders 98
References 98
X
Chapter 8: Cardiovascular Diseases and Diabetes Mellitus
8.1 Cardiovascular Diseases 102
8.1.1 Hypertension 102
Erythrocyte Aggregation and Deformability 103
8.1.2 Myocardial Infarction 104
8.1.3 Atherosclerosis 105
8.1.4 Cerebral Ischemia 106
8.2 Diabetes Mellitus 106
8.2.1 Blood and Plasma Viscosity 108
8.2.2 Erythrocyte Aggregation and Deformability 109
8.2.3 Fluidity of Erythrocyte Membrane 110
8.2.4 Factors Affecting Measurements 111
References 111
Chapter 9: Therapeutical Applications
9.1 Hemorheological Therapies 117
9.1.1 Hemodilution 117
9.2 Clinical Studies 119
9.2.1 Cerebral Ischemia 119
9.2.2 Ischemia of the Leg 120
9.3 Apheresis 120
9.4 Defibrinating Agents 121
9.5 Oral Drugs 122
9.5.1 Pentoxifylline (Oxpentifylline) 122
9.5.2 Buflomedil 122
9.5.3 Cyclo 3 Fort and Its Constituents 123
9.5.4 Gemfrozil 123
9.5.5 Fenofibrate 123
Exercise and Diet Control 123
References 123
Subject Index 127
|
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| id | DE-604.BV012467913 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T18:28:06Z |
| institution | BVB |
| isbn | 9051994354 4274902625 |
| language | English |
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| physical | X, 128 S. graph. Darst. |
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| series | Biomedical and health research |
| series2 | Biomedical and health research |
| spelling | Stolz, John F. Verfasser aut Hemorheology in practice by J.-F. Stolz ; M.Singh ; P.Riha Amsterdam [u.a.] IOS Press [u.a.] 1999 X, 128 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Biomedical and health research 30 Hémorhéologie Sang - Viscosité ram Blood Viscosity Blood Pathophysiology Blood Rheology Cardiovascular Diseases physiopathology Hematologic Diseases physiopathology Hemorheology Hämorrheologie (DE-588)4123326-8 gnd rswk-swf Hämorrheologie (DE-588)4123326-8 s DE-604 Singh, Megha Verfasser aut Riha, Pavel Verfasser aut Biomedical and health research 30 (DE-604)BV009680083 30 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008461559&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Stolz, John F. Singh, Megha Riha, Pavel Hemorheology in practice Biomedical and health research Hémorhéologie Sang - Viscosité ram Blood Viscosity Blood Pathophysiology Blood Rheology Cardiovascular Diseases physiopathology Hematologic Diseases physiopathology Hemorheology Hämorrheologie (DE-588)4123326-8 gnd |
| subject_GND | (DE-588)4123326-8 |
| title | Hemorheology in practice |
| title_auth | Hemorheology in practice |
| title_exact_search | Hemorheology in practice |
| title_full | Hemorheology in practice by J.-F. Stolz ; M.Singh ; P.Riha |
| title_fullStr | Hemorheology in practice by J.-F. Stolz ; M.Singh ; P.Riha |
| title_full_unstemmed | Hemorheology in practice by J.-F. Stolz ; M.Singh ; P.Riha |
| title_short | Hemorheology in practice |
| title_sort | hemorheology in practice |
| topic | Hémorhéologie Sang - Viscosité ram Blood Viscosity Blood Pathophysiology Blood Rheology Cardiovascular Diseases physiopathology Hematologic Diseases physiopathology Hemorheology Hämorrheologie (DE-588)4123326-8 gnd |
| topic_facet | Hémorhéologie Sang - Viscosité Blood Viscosity Blood Pathophysiology Blood Rheology Cardiovascular Diseases physiopathology Hematologic Diseases physiopathology Hemorheology Hämorrheologie |
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