Differential ion mobility spectrometry: nonlinear ion transport and fundamentals of FAIMS
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Format: | Buch |
Sprache: | English |
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CRC Press
2009
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Beschreibung: | XXIX, 299 S. graph. Darst. |
ISBN: | 9781420051063 |
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020 | |a 9781420051063 |9 978-1-4200-5106-3 | ||
035 | |a (OCoLC)261404152 | ||
035 | |a (DE-599)BSZ303419164 | ||
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084 | |a CHE 236f |2 stub | ||
100 | 1 | |a Shvartsburg, Alexandre A. |e Verfasser |4 aut | |
245 | 1 | 0 | |a Differential ion mobility spectrometry |b nonlinear ion transport and fundamentals of FAIMS |c Alexandre A. Shvartsburg |
264 | 1 | |a Boca Raton [u.a.] |b CRC Press |c 2009 | |
300 | |a XXIX, 299 S. |b graph. Darst. | ||
336 | |b txt |2 rdacontent | ||
337 | |b n |2 rdamedia | ||
338 | |b nc |2 rdacarrier | ||
650 | 4 | |a Ion mobility spectroscopy | |
650 | 0 | 7 | |a Ionenbeweglichkeitsspektroskopie |0 (DE-588)4349293-9 |2 gnd |9 rswk-swf |
689 | 0 | 0 | |a Ionenbeweglichkeitsspektroskopie |0 (DE-588)4349293-9 |D s |
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856 | 4 | 2 | |m Digitalisierung UB Bayreuth |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016769712&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
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Datensatz im Suchindex
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adam_text | Contents
Preface
......................................................................................................................ix
Acknowledgments
...................................................................................................xv
Author
...................................................................................................................xvii
Nomenclature of Physical Variables and Constants Found in the Book
..............xix
Chapter
1
Separation and Characterization of Molecules and Ions
Using Gas-Phase Transport
................................................................. 1
1.1
Physical Foundation and Definitions
............................................................. 1
1.2
Characterization of Molecules by Diffusion Measurements
.........................3
1.2.1
Fundamentals of Diffusion in Gases
................................................3
1.2.2
Use of Gas-Phase Diffusion to Elucidate the Structure
of Neutral Molecules
........................................................................4
1.3
IMS: Ion Dynamics and Consequent General Features
................................5
1.3.1
IMS
—
A Vindication of Aristotle s Physics
.....................................5
1.3.2
IMS and MS Dynamic Regimes
.......................................................8
1.3.3
Other Constraints on the IMS Gas Pressure
................................... 10
1.3.4
Diffusional Broadening of Ion Packets and IMS
Separation Power
............................................................................ 12
1.3.5
Space-Charge Phenomena in IMS and MS
.................................... 16
1.3.6
Flexibility of IMS Methods Provided by Gas Selection
................ 18
1.3.7
Chiral Separations Using IMS
........................................................24
1.3.8
Effects of Temperature and Pressure on IMS Resolution:
Benefits and Limitations of Cooling
...............................................26
1.3.9
Temperature of Ions in IMS and Its Effect
on Ion Geometries
...........................................................................29
1.3.10
Speed of IMS Methods: Between Liquid
Separations and MS
........................................................................31
1.4
Relating IMS Data to Molecular Structure
..................................................33
1.4.1
Feasibility and Fundamental Limitations of Ion Mobility
Calculations
.....................................................................................33
1.4.2
Overall Formalisms of Ion Mobility Calculations
..........................35
1.4.3
Approximations Using Hard-Sphere Potentials
..............................38
1.4.4
More Sophisticated Treatments of Attractive and Repulsive
Interactions
......................................................................................42
1.4.5
Speed of Ion Mobility Calculations
................................................45
1.4.6
Relevance to Differential IMS
........................................................47
References
...............................................................................................................48
Chapter
2
Fundamentals of High-Field Ion Mobility and Diffusion
.................55
2.1
General Aspects of High-Field Ion Mobility Standard
and
Nonstandard
Effects
..............................................................................55
2.2
Standard High-Field Effect
..........................................................................57
2.2.1
Low-Field Limit and Onset of High-Field Regime
..........................57
2.2.2
Types of KiE/N) and Its Form in the High-Field Limit
..................60
2.2.3
Dependence of K(E/N) at Intermediate Fields
on the Interaction Potential
...............................................................62
2.2.4
Diffusion in the High-Field Regime
.................................................66
2.2.5
Corrections to Mobility Equations in the High-Field Regime
.........73
2.3
Clustering of Gas Molecules on Ions and the Standard High-Field Effect
.....74
2.4
Non-Blanc Phenomena in High-Field Ion Transport
..................................78
2.4.1
Formalism for Ion Mobilities in Gas Mixtures
................................78
2.4.2
Ion Mobilities in Realistic Mixtures at High E/N
............................80
2.4.3
High-Field Ion Diffusion in Gas Mixtures
.......................................85
2.5
Vibrationally Inelastic Collisions
.................................................................87
2.5.1
Effect of Inelastic Energy Loss on Ion Mobility
..............................87
2.5.2
Inelastic Collisions and Ion Diffusion
..............................................92
2.6
Rotational Inelasticity and Collisional Alignment of Ions
..........................94
2.6.1
Rotational Heating of Polyatomic Molecules and Ions
....................94
2.6.2
Collisional Alignment
.......................................................................96
2.7
Dipole
Alignment of Ions
............................................................................99
2.7.1
Dipole
Alignment in Vacuum
...........................................................99
2.7.2
Fundamentals of the
Dipole
Alignment for Ions in Gases
............. 102
2.7.3
Dipole
Alignment under Practical IMS Conditions
....................... 108
2.7.4
Importance of the Induced
Dipole
.................................................. 112
2.8
Unstable High-Field Mobility of Runaway Ions
....................................... 114
2.9
Summary and Significance for Differential IMS
.......................................
П6
References
.............................................................................................................117
Chapter
3
Conceptual Implementation of Differential IMS
and Separation Properties of
FAIMS
..............................................125
3.1
Strategy for Optimum Differential Ion Mobility Separations
................... 126
3.1.1
Paradigm of Differential IMS in Asymmetric Electric Field
.........126
3.1.2
Ideal
FAIMS
Waveform
................................................................. 128
3.1.3
Practical Waveforms Based on Harmonic Oscillations
.................. 136
3.1.4
Global Waveform Optimization
..................................................... 142
3.1.5
Comparative Performance of Different Waveform Classes
........... 146
3.1.6
Optimum Waveforms in Realistic
FAIMS
Regimes
...................... 147
3.1.7
Waveform Optimization for Targeted Analyses
............................. 149
3.2
Limitations on the Differential IMS Paradigm That Shape
FAIMS
Approach
.......................................................................................
151
3.2.1
Hysteresis of Ion Motion
—
A Physical Limitation
of the Differential
ГМЅ
Approach
.................................................. 151
3.2.2
Are Dispersive
FAIMS
Separators Feasible?
.................................152
Contents
vii
3.2.3
FAIMS
Filtering Using Compensation Field
................................. 155
3.2.4
Comparison of a(E/N) Obtained from
FAIMS
and Conventional IMS
.................................................................... 161
3.3
Trends of
FAIMS
Separation Parameters
.................................................. 161
3.3.1
How Should
FAIMS Data
Be Reported?
....................................... 161
3.3.2
Ion Classification by the Shape of £c(£d) Curves
......................... 163
3.3.3
Dependence
oï
Ec on the Ion and Gas Properties
and Relationship to DT IMS Data
.................................................. 165
3.3.4
Importance of Gas Temperature
..................................................... 169
3.3.5
Pendular
Ions in
FAIMS:
The Matter of Rotational Hysteresis
..... 172
3.4
Separations in Heteromolecular Media
...................................................... 174
3.4.1
Analyses in Mixed Gas Buffers
...................................................... 174
3.4.2
Use of Vapor-Containing Buffers
................................................... 179
3.4.3
Separation of Ions in Related Vapors
............................................. 184
3.4.4
Effect of Ion Solvation
................................................................... 185
3.5
Ion Transformations inside
FAIMS
and Effect on Separation
Performance
............................................................................................... 187
3.5.1
Consequences of Ion Reactions during
FAIMS
Analyses
............. 187
3.5.2
Endothermic Processes: Control by the Average
or Maximum Ion Temperature?
...................................................... 190
3.5.3
Direct Characterization of Heat-Induced Processes
in
FAIMS
Using Spectral Normalization
....................................... 194
3.5.4
Varying the Ion Heating in
FAIMS
and Suppressing
Ion Transformations in cryo-FAIMS
.......................................... 197
3.5.5
In-Source Decay in
FAIMS
and Eq/Eo Maps
........................... 199
References
.............................................................................................................200
Chapter
4
Separation Performance of
FAIMS
and Its Control
via Instrumental Parameters
.............................................................205
4.1
Approaches to Simulation of
FAIMS
Operation
.......................................206
4.1.1
Trajectory Propagation Methods
.....................................................206
4.1.2
Emulations of a Diffusing Fluid
.....................................................209
4.2
Separation Properties in Homogeneous Electric Field
..............................210
4.2.1
FAIMS
Performance in Short and Long Regimes:
Control of Separation Time
............................................................210
4.2.2
Lateral Ion Motion:
Nonuniform Gas
Flow in Flow-Driven
FAIMS
and Axial Diffusion
...........................................................215
4.2.3
Effect of the Ion Mobility and Charge State on Separation
Metrics in Flow-Driven
FAIMS
.....................................................218
4.2.4
Dependence of Separation Metrics on the Gap Width
and Optimum Width
.......................................................................219
4.2.5
Discrimination of Ions Based on Diffusion Speed
and Its Reduction in Field-Driven Systems
....................................221
4.2.6
FAIMS
Analyses at Reduced Gas Pressure
....................................224
Vl Contents
4.3
Ion Focusing in Inhomogeneous Fields and Consequences
for
FAIMS
Performance
............................................................................226
4.3.1
Fundamentals of Ion Focusing: Three Focusing Regimes
in Curved Gaps
.............................................................................226
4.3.2
Determination of Waveform Polarity and Ion Classification
by Focusing Properties
.................................................................229
4.3.3
Saturation of Ion Current and Discrimination Based
on Focusing Strength
....................................................................230
4.3.4
Dependence of Separation Metrics on Instrument Parameters
in Curved
FAIMS
.........................................................................234
4.3.5
Spectral Peak Shape: Space Charge or Spontaneous
Redistribution?
............................................................................239
4.3.6
Imperfect Waveforms: Noise and Ripple
.....................................241
4.3.7
Resolution/Sensitivity Diagrams: Advantages of Planar
FAIMS
and High-Frequency Ripple
............................................244
4.3.8
Dispersion Field Gradient and Compensation Field Shifts
in Curved
FAIMS
.........................................................................246
4.3.9
Ion Focusing by Thermal Gradient in the Gas
.............................250
4.3.10
Separations in Multigeometry Gaps: Dome
and Hook
FAIMS
.....................................................................252
4.3.11
Effect of Scanning Speed and Direction
on
FAIMS
Performance
................................................................257
References
.............................................................................................................259
Chapter
5
Beyond
FAIMS: New
Concepts in Nonlinear Ion Mobility
Spectrometry
....................................................................................263
5.1
Ion Guidance and Trapping at Atmospheric Pressure
...............................263
5.1.1
Previous Methods for Manipulation of Ions in Gases
..................263
5.1.2
Ion Guidance by Means of the
FAIMS
Effect
.............................265
5.1.3
Ion Trapping in Spherical
FAIMS
................................................267
5.2
Higher-Order Differential (HOD) IMS Methods
.......................................270
5.2.1
Fundamentals of HOD IMS
..........................................................270
5.2.2
Practical Aspects of HOD IMS Implementation, Limitations
on the Separation Order
................................................................275
5.2.3
Orthogonality of HOD IMS Separations to MS
and Conventional IMS
..................................................................279
5.3
Ion Mobility Spectrometry with Alignment of
Dipole
Direction (IMS-ADD)
................................................................................283
5.3.1
Filtering IMS-ADD Based on the Cross Section Orthogonal
to the Ion
Dipole...........................................................................284
5.3.2
Dispersive IMS-ADD Based on the Average Cross Section
Parallel to the Ion
Dipole..............................................................287
5.3.3
Combined MS-ADD Analyses
....................................................288
References
.............................................................................................................289
Index
.....................................................................................................................293
|
adam_txt |
Contents
Preface
.ix
Acknowledgments
.xv
Author
.xvii
Nomenclature of Physical Variables and Constants Found in the Book
.xix
Chapter
1
Separation and Characterization of Molecules and Ions
Using Gas-Phase Transport
. 1
1.1
Physical Foundation and Definitions
. 1
1.2
Characterization of Molecules by Diffusion Measurements
.3
1.2.1
Fundamentals of Diffusion in Gases
.3
1.2.2
Use of Gas-Phase Diffusion to Elucidate the Structure
of Neutral Molecules
.4
1.3
IMS: Ion Dynamics and Consequent General Features
.5
1.3.1
IMS
—
A Vindication of Aristotle's Physics
.5
1.3.2
IMS and MS Dynamic Regimes
.8
1.3.3
Other Constraints on the IMS Gas Pressure
. 10
1.3.4
Diffusional Broadening of Ion Packets and IMS
Separation Power
. 12
1.3.5
Space-Charge Phenomena in IMS and MS
. 16
1.3.6
Flexibility of IMS Methods Provided by Gas Selection
. 18
1.3.7
Chiral Separations Using IMS
.24
1.3.8
Effects of Temperature and Pressure on IMS Resolution:
Benefits and Limitations of Cooling
.26
1.3.9
Temperature of Ions in IMS and Its Effect
on Ion Geometries
.29
1.3.10
Speed of IMS Methods: Between Liquid
Separations and MS
.31
1.4
Relating IMS Data to Molecular Structure
.33
1.4.1
Feasibility and Fundamental Limitations of Ion Mobility
Calculations
.33
1.4.2
Overall Formalisms of Ion Mobility Calculations
.35
1.4.3
Approximations Using Hard-Sphere Potentials
.38
1.4.4
More Sophisticated Treatments of Attractive and Repulsive
Interactions
.42
1.4.5
Speed of Ion Mobility Calculations
.45
1.4.6
Relevance to Differential IMS
.47
References
.48
Chapter
2
Fundamentals of High-Field Ion Mobility and Diffusion
.55
2.1
General Aspects of High-Field Ion Mobility Standard
and
Nonstandard
Effects
.55
2.2
Standard High-Field Effect
.57
2.2.1
Low-Field Limit and Onset of High-Field Regime
.57
2.2.2
Types of KiE/N) and Its Form in the High-Field Limit
.60
2.2.3
Dependence of K(E/N) at Intermediate Fields
on the Interaction Potential
.62
2.2.4
Diffusion in the High-Field Regime
.66
2.2.5
Corrections to Mobility Equations in the High-Field Regime
.73
2.3
Clustering of Gas Molecules on Ions and the Standard High-Field Effect
.74
2.4
Non-Blanc Phenomena in High-Field Ion Transport
.78
2.4.1
Formalism for Ion Mobilities in Gas Mixtures
.78
2.4.2
Ion Mobilities in Realistic Mixtures at High E/N
.80
2.4.3
High-Field Ion Diffusion in Gas Mixtures
.85
2.5
Vibrationally Inelastic Collisions
.87
2.5.1
Effect of Inelastic Energy Loss on Ion Mobility
.87
2.5.2
Inelastic Collisions and Ion Diffusion
.92
2.6
Rotational Inelasticity and Collisional Alignment of Ions
.94
2.6.1
Rotational Heating of Polyatomic Molecules and Ions
.94
2.6.2
Collisional Alignment
.96
2.7
Dipole
Alignment of Ions
.99
2.7.1
Dipole
Alignment in Vacuum
.99
2.7.2
Fundamentals of the
Dipole
Alignment for Ions in Gases
. 102
2.7.3
Dipole
Alignment under Practical IMS Conditions
. 108
2.7.4
Importance of the Induced
Dipole
. 112
2.8
Unstable High-Field Mobility of Runaway Ions
. 114
2.9
Summary and Significance for Differential IMS
.
П6
References
.117
Chapter
3
Conceptual Implementation of Differential IMS
and Separation Properties of
FAIMS
.125
3.1
Strategy for Optimum Differential Ion Mobility Separations
. 126
3.1.1
Paradigm of Differential IMS in Asymmetric Electric Field
.126
3.1.2
Ideal
FAIMS
Waveform
. 128
3.1.3
Practical Waveforms Based on Harmonic Oscillations
. 136
3.1.4
Global Waveform Optimization
. 142
3.1.5
Comparative Performance of Different Waveform Classes
. 146
3.1.6
Optimum Waveforms in Realistic
FAIMS
Regimes
. 147
3.1.7
Waveform Optimization for Targeted Analyses
. 149
3.2
Limitations on the Differential IMS Paradigm That Shape
FAIMS
Approach
.
151
3.2.1
Hysteresis of Ion Motion
—
A Physical Limitation
of the Differential
ГМЅ
Approach
. 151
3.2.2
Are Dispersive
FAIMS
Separators Feasible?
.152
Contents
vii
3.2.3
FAIMS
Filtering Using Compensation Field
. 155
3.2.4
Comparison of a(E/N) Obtained from
FAIMS
and Conventional IMS
. 161
3.3
Trends of
FAIMS
Separation Parameters
. 161
3.3.1
How Should
FAIMS Data
Be Reported?
. 161
3.3.2
Ion Classification by the Shape of £c(£d) Curves
. 163
3.3.3
Dependence
oï
Ec on the Ion and Gas Properties
and Relationship to DT IMS Data
. 165
3.3.4
Importance of Gas Temperature
. 169
3.3.5
Pendular
Ions in
FAIMS:
The Matter of Rotational Hysteresis
. 172
3.4
Separations in Heteromolecular Media
. 174
3.4.1
Analyses in Mixed Gas Buffers
. 174
3.4.2
Use of Vapor-Containing Buffers
. 179
3.4.3
Separation of Ions in Related Vapors
. 184
3.4.4
Effect of Ion Solvation
. 185
3.5
Ion Transformations inside
FAIMS
and Effect on Separation
Performance
. 187
3.5.1
Consequences of Ion Reactions during
FAIMS
Analyses
. 187
3.5.2
Endothermic Processes: Control by the Average
or Maximum Ion Temperature?
. 190
3.5.3
Direct Characterization of Heat-Induced Processes
in
FAIMS
Using Spectral Normalization
. 194
3.5.4
Varying the Ion Heating in
FAIMS
and Suppressing
Ion Transformations in "cryo-FAIMS"
. 197
3.5.5
"In-Source Decay" in
FAIMS
and Eq/Eo Maps
. 199
References
.200
Chapter
4
Separation Performance of
FAIMS
and Its Control
via Instrumental Parameters
.205
4.1
Approaches to Simulation of
FAIMS
Operation
.206
4.1.1
Trajectory Propagation Methods
.206
4.1.2
Emulations of a Diffusing Fluid
.209
4.2
Separation Properties in Homogeneous Electric Field
.210
4.2.1
FAIMS
Performance in "Short" and "Long" Regimes:
Control of Separation Time
.210
4.2.2
Lateral Ion Motion:
Nonuniform Gas
Flow in Flow-Driven
FAIMS
and Axial Diffusion
.215
4.2.3
Effect of the Ion Mobility and Charge State on Separation
Metrics in Flow-Driven
FAIMS
.218
4.2.4
Dependence of Separation Metrics on the Gap Width
and Optimum Width
.219
4.2.5
Discrimination of Ions Based on Diffusion Speed
and Its Reduction in Field-Driven Systems
.221
4.2.6
FAIMS
Analyses at Reduced Gas Pressure
.224
Vl" Contents
4.3
Ion Focusing in Inhomogeneous Fields and Consequences
for
FAIMS
Performance
.226
4.3.1
Fundamentals of Ion Focusing: Three Focusing Regimes
in Curved Gaps
.226
4.3.2
Determination of Waveform Polarity and Ion Classification
by Focusing Properties
.229
4.3.3
Saturation of Ion Current and Discrimination Based
on Focusing Strength
.230
4.3.4
Dependence of Separation Metrics on Instrument Parameters
in Curved
FAIMS
.234
4.3.5
Spectral Peak Shape: Space Charge or "Spontaneous
Redistribution?"
.239
4.3.6
Imperfect Waveforms: Noise and Ripple
.241
4.3.7
Resolution/Sensitivity Diagrams: Advantages of Planar
FAIMS
and High-Frequency Ripple
.244
4.3.8
Dispersion Field Gradient and Compensation Field Shifts
in Curved
FAIMS
.246
4.3.9
Ion Focusing by Thermal Gradient in the Gas
.250
4.3.10
Separations in "Multigeometry" Gaps: "Dome"
and "Hook"
FAIMS
.252
4.3.11
Effect of Scanning Speed and Direction
on
FAIMS
Performance
.257
References
.259
Chapter
5
Beyond
FAIMS: New
Concepts in Nonlinear Ion Mobility
Spectrometry
.263
5.1
Ion Guidance and Trapping at Atmospheric Pressure
.263
5.1.1
Previous Methods for Manipulation of Ions in Gases
.263
5.1.2
Ion Guidance by Means of the
FAIMS
Effect
.265
5.1.3
Ion Trapping in Spherical
FAIMS
.267
5.2
Higher-Order Differential (HOD) IMS Methods
.270
5.2.1
Fundamentals of HOD IMS
.270
5.2.2
Practical Aspects of HOD IMS Implementation, Limitations
on the Separation Order
.275
5.2.3
Orthogonality of HOD IMS Separations to MS
and Conventional IMS
.279
5.3
Ion Mobility Spectrometry with Alignment of
Dipole
Direction (IMS-ADD)
.283
5.3.1
Filtering IMS-ADD Based on the Cross Section Orthogonal
to the Ion
Dipole.284
5.3.2
Dispersive IMS-ADD Based on the Average Cross Section
Parallel to the Ion
Dipole.287
5.3.3
Combined MS-ADD Analyses
.288
References
.289
Index
.293 |
any_adam_object | 1 |
any_adam_object_boolean | 1 |
author | Shvartsburg, Alexandre A. |
author_facet | Shvartsburg, Alexandre A. |
author_role | aut |
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discipline_str_mv | Chemie / Pharmazie Physik Chemie |
format | Book |
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id | DE-604.BV035101742 |
illustrated | Illustrated |
index_date | 2024-07-02T22:14:25Z |
indexdate | 2024-07-09T21:22:15Z |
institution | BVB |
isbn | 9781420051063 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-016769712 |
oclc_num | 261404152 |
open_access_boolean | |
owner | DE-703 DE-91G DE-BY-TUM DE-11 |
owner_facet | DE-703 DE-91G DE-BY-TUM DE-11 |
physical | XXIX, 299 S. graph. Darst. |
publishDate | 2009 |
publishDateSearch | 2009 |
publishDateSort | 2009 |
publisher | CRC Press |
record_format | marc |
spelling | Shvartsburg, Alexandre A. Verfasser aut Differential ion mobility spectrometry nonlinear ion transport and fundamentals of FAIMS Alexandre A. Shvartsburg Boca Raton [u.a.] CRC Press 2009 XXIX, 299 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Ion mobility spectroscopy Ionenbeweglichkeitsspektroskopie (DE-588)4349293-9 gnd rswk-swf Ionenbeweglichkeitsspektroskopie (DE-588)4349293-9 s DE-604 Digitalisierung UB Bayreuth application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016769712&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Shvartsburg, Alexandre A. Differential ion mobility spectrometry nonlinear ion transport and fundamentals of FAIMS Ion mobility spectroscopy Ionenbeweglichkeitsspektroskopie (DE-588)4349293-9 gnd |
subject_GND | (DE-588)4349293-9 |
title | Differential ion mobility spectrometry nonlinear ion transport and fundamentals of FAIMS |
title_auth | Differential ion mobility spectrometry nonlinear ion transport and fundamentals of FAIMS |
title_exact_search | Differential ion mobility spectrometry nonlinear ion transport and fundamentals of FAIMS |
title_exact_search_txtP | Differential ion mobility spectrometry nonlinear ion transport and fundamentals of FAIMS |
title_full | Differential ion mobility spectrometry nonlinear ion transport and fundamentals of FAIMS Alexandre A. Shvartsburg |
title_fullStr | Differential ion mobility spectrometry nonlinear ion transport and fundamentals of FAIMS Alexandre A. Shvartsburg |
title_full_unstemmed | Differential ion mobility spectrometry nonlinear ion transport and fundamentals of FAIMS Alexandre A. Shvartsburg |
title_short | Differential ion mobility spectrometry |
title_sort | differential ion mobility spectrometry nonlinear ion transport and fundamentals of faims |
title_sub | nonlinear ion transport and fundamentals of FAIMS |
topic | Ion mobility spectroscopy Ionenbeweglichkeitsspektroskopie (DE-588)4349293-9 gnd |
topic_facet | Ion mobility spectroscopy Ionenbeweglichkeitsspektroskopie |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016769712&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
work_keys_str_mv | AT shvartsburgalexandrea differentialionmobilityspectrometrynonlineariontransportandfundamentalsoffaims |