Development and implementation of alternative approaches to animal testing in toxicology for the regulatory assessment of substances and products:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Enth. 14 Sonderabdr. aus verschiedenen Zeitschr. |
| Beschreibung: | 50 Bl., [197] S. in getr. Zählung Ill., graph. Darst. 30 cm |
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Datensatz im Suchindex
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| adam_text | IMAGE 1
CONTENTS
ZUSAMMENFASSUNG 6
EXECUTIVE SUMMARY 7
1. INTRODUCTION AND BACKGROUND 8
1.1 SCOPE 8
1.2 THE REGULATORY FRAMEWORK IN THE EU 9
1.3 ACTORS IN THE FIELD AND THE ROLE OF SCIENCE 12
1.4 VALIDATION, ACCEPTANCE AND IMPLEMENTATION OF ALTERNATIVE METHODS 14
1.5 USE OF METHODS AND APPROACHES IN HAZARD AND RISK ASSESSMENT CONCEPTS
16
2. ASSESSMENT O F SPECIFIC TOXICOIOGICAI EFFECTS WITH ALTERNATIVE
APPROACHES 19
2.1 LOCAL EFFECTS: SKIN AND EYE IRRITATION & CORROSION 19
2.1.1 SKIN EFFECTS 19
2.1.2 EYE EFFECTS 20
2.2 SKIN SENSITIZATION 21
2.3 ACUTE SYSTEMIC TOXICITY 23
2.4 GENOTOXICITY 24
2.5 CARCINOGENICITY 26
2.6 TOXICOKINETICS (ADME) 27
2.7 RISK ASSESSMENT OF SMALL PARTICLES 29
3. CONCLUDING REMARKS 31
4. REFERENCES 32
5. LIST O F FIGURES AND TABLES 36
6. GLOSSARY 37
7. CURRICULUM VITAE 39
8. LIST O F SELECTED ARTICLES 41
9. LIST O F ADDITIONAL SCIENTIFIC PUBLICATIONS 44
10. ANNEX 49
HTTP://D-NB.INFO/1031978003
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| title | Development and implementation of alternative approaches to animal testing in toxicology for the regulatory assessment of substances and products |
| title_auth | Development and implementation of alternative approaches to animal testing in toxicology for the regulatory assessment of substances and products |
| title_exact_search | Development and implementation of alternative approaches to animal testing in toxicology for the regulatory assessment of substances and products |
| title_full | Development and implementation of alternative approaches to animal testing in toxicology for the regulatory assessment of substances and products vorgelegt von Julia Scheel |
| title_fullStr | Development and implementation of alternative approaches to animal testing in toxicology for the regulatory assessment of substances and products vorgelegt von Julia Scheel |
| title_full_unstemmed | Development and implementation of alternative approaches to animal testing in toxicology for the regulatory assessment of substances and products vorgelegt von Julia Scheel |
| title_short | Development and implementation of alternative approaches to animal testing in toxicology for the regulatory assessment of substances and products |
| title_sort | development and implementation of alternative approaches to animal testing in toxicology for the regulatory assessment of substances and products |
| topic_facet | Hochschulschrift |
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