Identification and characterisation of novel modulators of the transient receptor potential channel TRPC5:
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| Format: | Abschlussarbeit Elektronisch Software E-Book |
| Sprache: | English |
| Veröffentlicht: |
Leipzig
[2017]
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| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 1 CD-ROM (iv, 72 Blätter, 5 ungezählte Blätter) Illustrationen, Diagramme |
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| 100 | 1 | |a Richter, Julia Magdalena |d 1982- |e Verfasser |0 (DE-588)1136930736 |4 aut | |
| 245 | 1 | 0 | |a Identification and characterisation of novel modulators of the transient receptor potential channel TRPC5 |c vorgelegt von Diplom-Biologin Julia Magdalena Richter |
| 264 | 1 | |a Leipzig |c [2017] | |
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Datensatz im Suchindex
| _version_ | 1804178125239615488 |
|---|---|
| adam_text | CONTENTS
1.
ABSTRACT...............................................................................................................................
1
2.
ZUSAMMENFASSUNG..............................................................................................................
5
3.
INTRODUCTION........................................................................................................................
9
3.1. CLASSIFICATION AND TRANSMEMBRANE TOPOLOGY OF ION
CHANNELS..........................................9
3.2. TRANSIENT RECEPTOR POTENTIAL CHANNELS
(TRP).................................................................10
3.3. TRPC
CHANNELS.............................................................................................................
12
3.3.1. PHYSIOLOGICAL
FUNCTION............................................................................................13
3.3.2. FUNCTIONAL DOMAINS AND CHANNEL
STRUCTURE..............................................................14
3.3.3. PORE AND ION PERMEATION
PATHWAY...........................................................................15
3.3.5. BIOPHYSICAL DESCRIPTION
........................................................................................
16
3.4. TRPC5 CHANNEL
MODULATORS...........................................................................................17
3.4.1. ACTIVATION OF TRPC5
CHANNELS...............................................................................17
3.4.2. INHIBITION OF TRPC5
CHANNELS...............................................................................
25
3.5. AIM OF THE
THESIS...........................................................................................................
29
3.6. RELATIONSHIP OF THE
PUBLICATIONS...................................................................................
29
4.
PUBLICATIONS......................................................................................................................
31
4.1. RILUZOLE ACTIVATES TRPC5 CHANNELS INDEPENDENTLY OF PLC ACTIVITY
............................
31
4.2. CLEMIZOLE HYDROCHLORIDE IS A NOVEL AND POTENT INHIBITOR OF
TRANSIENT RECEPTOR
POTENTIAL CHANNEL
TRPC5.............................................................................................
48
5.
REFERENCES........................................................................................................................
60
|
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| spelling | Richter, Julia Magdalena 1982- Verfasser (DE-588)1136930736 aut Identification and characterisation of novel modulators of the transient receptor potential channel TRPC5 vorgelegt von Diplom-Biologin Julia Magdalena Richter Leipzig [2017] 1 CD-ROM (iv, 72 Blätter, 5 ungezählte Blätter) Illustrationen, Diagramme txt rdacontent c rdamedia cd rdacarrier Dissertation Universität Leipzig 2017 (DE-588)4113937-9 Hochschulschrift gnd-content (DE-588)4139307-7 CD-ROM gnd-carrier DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030072189&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Textdatei PDF |
| spellingShingle | Richter, Julia Magdalena 1982- Identification and characterisation of novel modulators of the transient receptor potential channel TRPC5 |
| subject_GND | (DE-588)4113937-9 (DE-588)4139307-7 |
| title | Identification and characterisation of novel modulators of the transient receptor potential channel TRPC5 |
| title_auth | Identification and characterisation of novel modulators of the transient receptor potential channel TRPC5 |
| title_exact_search | Identification and characterisation of novel modulators of the transient receptor potential channel TRPC5 |
| title_full | Identification and characterisation of novel modulators of the transient receptor potential channel TRPC5 vorgelegt von Diplom-Biologin Julia Magdalena Richter |
| title_fullStr | Identification and characterisation of novel modulators of the transient receptor potential channel TRPC5 vorgelegt von Diplom-Biologin Julia Magdalena Richter |
| title_full_unstemmed | Identification and characterisation of novel modulators of the transient receptor potential channel TRPC5 vorgelegt von Diplom-Biologin Julia Magdalena Richter |
| title_short | Identification and characterisation of novel modulators of the transient receptor potential channel TRPC5 |
| title_sort | identification and characterisation of novel modulators of the transient receptor potential channel trpc5 |
| topic_facet | Hochschulschrift CD-ROM |
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