Molecular biology of the toxic response:
Saved in:
| Other Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Philadelphia, PA
Taylor & Francis
[1999]
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | xviii, 581 Seiteeiten Illustrationen, Diagramme |
| ISBN: | 1560325925 |
Staff View
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| 245 | 1 | 0 | |a Molecular biology of the toxic response |c edited by Alvaro Puga, Ph.D., University of Cincinnati Medial Center, Cincinnati, Ohio ; Kendall B. Wallace, Ph.D., D.A.B.T., University of Minnesota School of Medicine, Duluth, Minnesota |
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| 650 | 4 | |a Molecular toxicology | |
| 650 | 4 | |a Mutagenicity Tests | |
| 650 | 4 | |a Mutagens |x toxicity | |
| 650 | 4 | |a Signal Transduction |x drug effects | |
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Record in the Search Index
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| adam_text | CONTENTS
Contributors ix
Foreword xiii
Preface xvii
Part I
IDENTIFICATION OF GENES OF TOXICOLOGIC RELEVANCE
CHAPTER 1
Analysis of Quantitative Traits 3
Christopher Haertel, Martin Heur, and Anil G. Menon
CHAPTER 2
Expression of the Transforming Growth Factor /J2 Gene: Strategies
for Deciphering the Mechanisms of Transcriptional Regulation 15
Bedta Scholtz and Angie Rizzino
CHAPTER 3
Potential Uses of Transgenic and Gene Targeted Animals in Toxicologic Research 27
Vicky Valancius Mangel and Thomas Doetschman
CHAPTER 4
Molecular Epidemiology of Lung Cancer 53
Kaname Kawajiri
CHAPTER 5
Polymorphisms of Genes of Toxicologic Significance 63
Urs A. Meyer
Part II
MOLECULAR INDICATORS OF EXPOSURE
TO GENOTOXIC CHEMICALS
CHAPTER 6
Mutational Specificity Analysis in Salmonella typhimurium 75
Walter H.Koch
vi Contents
CHAPTER 7
Mutational Analysis of Genotoxic Chemicals 93
Michael Seidman and Kathleen Dixon
CHAPTER 8
The Use of Transgenic Mice in Mutagenesis and Carcinogenesis Research and
in Chemical Safety Assessment 111
Michael StJ. Battalora and Raymond W. Tennant
CHAPTER 9
Molecular Biomarkers of Carcinogen Exposure 127
Glenn Talaska, Lisa Weider, and Penelope J. E. Quintana
CHAPTER 10
Biomarkers for Carcinogen Exposure: Tumor Initiation 145
Jia Sheng Wang and John D. Groopman
Part III
USES OF REPORTER GENES IN TOXICOLOGY
CHAPTER 11
Stress Response to DNA Damaging Agents 169
Shannon E. Beard and Marque D. Todd
CHAPTER 12
Reporter Genes in Toxicology 187
J. H. demons and Timothy R. Zacharewski
CHAPTER 13
Reporter Genes to Study Regulatory Mechanisms 205
Ronald N. Hines, Shamim A. Ansari, and Steven M. Smolinski
Part IV
MECHANISM OF ACTION OF NON GENOTOXIC COMPOUNDS
CHAPTER 14
Molecular Mechanisms of Hepatocarcinogenic Peroxisome Proliferators 219 |
Paula J. Lapinskas and J. Christopher Corton I
Contents vii
CHAPTER 15
Regulation of Nitric Oxide Synthesis and Neurotoxicity 255
Valina L. Dawson and Ted M. Dawson
CHAPTER 16
Estrogenic and Antiestrogenic Compounds 267
Weston Porter and Stephen H. Safe
CHAPTER 17
Xenoestrogens: Prevalence, Biologic Effects, and Mechanism of Action 285
Nira Ben Jonathan
CHAPTER 18
Metallothionein Transgenic and Knockout Mouse Models in the Study
of Cadmium Toxicity 299
Curtis D. Klaassen and Jie Liu
CHAPTER 19
Molecular Mechanisms and Genetic Determinants of Ozone Toxicity in the Lung 317
George D. Leikauf and Howard G. Shertzer
CHAPTER 20
Particle Induced Pulmonary Inflammation: Characterizing the Role
of the Chemokine MIP 2 337
Kevin E. Driscoll, Diana Hassenbein, Janet Carter, and Brian Howard
PartV
SIGNAL TRANSDUCTION IN TOXICOLOGY
CHAPTER 21
Simple Models of Dioxin Action 355
Lucy A. Carver and Christopher A. Bradfield
CHAPTER 22
Interactions of ARNT with AhR and HIF la 377
Markus R. Probst and Oliver Hankinson
CHAPTER 23
Natural and Synthetic Ligands for the Ah Receptor 393
Michael S. Denison, Shawn D. Seidel, William J. Rogers, Michael Ziccardi,
Greg M. Winter, and Sharon Heath Pag Huso
viii Contents
CHAPTER 24
Identifying Mechanisms of Developmental Toxicity: Application of Tools
from Molecular Biology 411
Sandra C. Kirchner and Elaine M. Faustman
CHAPTER 25
Dioxin and Teratogenesis 439
Barbara D. Abbott and Linda S. Birnbaum
CHAPTER 26
Heat Shock Proteins: Molecular Biomarkers of Effect 449
J. A. Ryan and Larry E. Hightower
CHAPTER 27
Oxidative Stress in Yeast 467
Bernhard Krems and Valeria Cizewski Culotta
CHAPTER 28
Signal Transduction Induced by Adverse Agents: Activation by Inhibition.
The UV Response 1997 479
Peter Herrlich, Hans J. Rahmsdorf, Klaus Bender, Christine Blattner,
and Axel Knebel
CHAPTER 29
Activation of Signal Transduction Pathways by Dioxins 493
Xinfang Ma and John G. Babish
CHAPTER 30
Ras Activation by Benzo[a]pyrene 517
Kenneth S. Ramos, Yong Zhang, and Christopher M. Bral
Part VI
COEVOLUTION OF TOXIC AND DETOXIFICATION PROCESSES
CHAPTER 31
Molecular Biology of Insecticide Resistance 533
Richard H. ffrench Constant, Yoonseong Park, and Rene Feyereisen
CHAPTER 32
Animal Plant Warfare: Molecular Basis for Cytochrome P450 Mediated
Natural Adaptation 553
May R. Berenbaum
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| isbn | 1560325925 |
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| physical | xviii, 581 Seiteeiten Illustrationen, Diagramme |
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| publisher | Taylor & Francis |
| record_format | marc |
| spelling | Molecular biology of the toxic response edited by Alvaro Puga, Ph.D., University of Cincinnati Medial Center, Cincinnati, Ohio ; Kendall B. Wallace, Ph.D., D.A.B.T., University of Minnesota School of Medicine, Duluth, Minnesota Philadelphia, PA Taylor & Francis [1999] xviii, 581 Seiteeiten Illustrationen, Diagramme txt rdacontent n rdamedia nc rdacarrier Genes, Reporter drug effects Molecular toxicology Mutagenicity Tests Mutagens toxicity Signal Transduction drug effects Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Toxikologie (DE-588)4060538-3 gnd rswk-swf Toxikologie (DE-588)4060538-3 s Molekularbiologie (DE-588)4039983-7 s DE-604 Puga, Alvaro (DE-588)1162524952 edt Wallace, Kendall Bruce (DE-588)1162524812 edt HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=008227497&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Molecular biology of the toxic response Genes, Reporter drug effects Molecular toxicology Mutagenicity Tests Mutagens toxicity Signal Transduction drug effects Molekularbiologie (DE-588)4039983-7 gnd Toxikologie (DE-588)4060538-3 gnd |
| subject_GND | (DE-588)4039983-7 (DE-588)4060538-3 |
| title | Molecular biology of the toxic response |
| title_auth | Molecular biology of the toxic response |
| title_exact_search | Molecular biology of the toxic response |
| title_full | Molecular biology of the toxic response edited by Alvaro Puga, Ph.D., University of Cincinnati Medial Center, Cincinnati, Ohio ; Kendall B. Wallace, Ph.D., D.A.B.T., University of Minnesota School of Medicine, Duluth, Minnesota |
| title_fullStr | Molecular biology of the toxic response edited by Alvaro Puga, Ph.D., University of Cincinnati Medial Center, Cincinnati, Ohio ; Kendall B. Wallace, Ph.D., D.A.B.T., University of Minnesota School of Medicine, Duluth, Minnesota |
| title_full_unstemmed | Molecular biology of the toxic response edited by Alvaro Puga, Ph.D., University of Cincinnati Medial Center, Cincinnati, Ohio ; Kendall B. Wallace, Ph.D., D.A.B.T., University of Minnesota School of Medicine, Duluth, Minnesota |
| title_short | Molecular biology of the toxic response |
| title_sort | molecular biology of the toxic response |
| topic | Genes, Reporter drug effects Molecular toxicology Mutagenicity Tests Mutagens toxicity Signal Transduction drug effects Molekularbiologie (DE-588)4039983-7 gnd Toxikologie (DE-588)4060538-3 gnd |
| topic_facet | Genes, Reporter drug effects Molecular toxicology Mutagenicity Tests Mutagens toxicity Signal Transduction drug effects Molekularbiologie Toxikologie |
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