The BRICHOS Domain: Its Proproteins and Functions
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cham [u.a.]
Springer International Publishing
2015
|
| Schriftenreihe: | SpringerBriefs in Molecular Science
|
| Schlagworte: | |
| Online-Zugang: | FAW01 UBT01 Volltext Inhaltsverzeichnis Abstract |
| Beschreibung: | 1 Online-Ressource (XV, 28 p. 13 illus. in color) |
| ISBN: | 9783319165646 |
| ISSN: | 2191-5407 |
| DOI: | 10.1007/978-3-319-16564-6 |
Internformat
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Datensatz im Suchindex
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|---|---|
| adam_text | THE BRICHOS DOMAIN
/ PRESTO, JENNY
: 2015
TABLE OF CONTENTS / INHALTSVERZEICHNIS
INTRODUCTION TO BRICHOS SUPERFAMILY
BRICHOS IN PROSP-C
PROTEINS WITH A BRICHOS DOMAIN
AΒ AMYLOID FORMATION IN ALZHEIMER S DISEASE
IN VIVO EFFECT OF BRICHOS ON AΒ AGGREGATION AND TOXICITY
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
THE BRICHOS DOMAIN
/ PRESTO, JENNY
: 2015
ABSTRACT / INHALTSTEXT
THIS BRIEF SUMMARIZES THE CURRENT RESEARCH ON THE NOVEL BRICHOS DOMAIN,
WHICH IS A CHAPERONE DOMAIN FOUND IN A VARIETY OF PROTEINS AND IS SHOWN
TO EXHIBIT ANTI-AMYLOIDOGENIC CHAPERONE-LIKE FUNCTIONS. THE BRICHOS
DOMAIN IS DEFINED FROM SEQUENCE SIMILARITIES, LACKS ESTABLISHED
PHYSIOLOGICAL FUNCTION(S) AND IS FOUND ABOUT 10 DISTANTLY RELATED
PRO-PROTEIN FAMILIES, SEVERAL OF WHICH ARE ASSOCIATED WITH HUMAN
DISEASE. IN THIS WORK, THE AUTHORS REVIEW THE MECHANISM BY WHICH BRICHOS
INHIBITS AΒ AGGREGATION AND EXAMINE RECENT RESULTS FROM IN VIVO
EXPERIMENTS WHERE BRICHOS INHIBITS AΒ AGGREGATION AND TOXICITY IN
DROSOPHILA MELANOGASTER. BRICHOS IS ONE OF NATURE´S (MORE SPECIFIC)
WAYS TO PROTECT AGAINST FIBRIL FORMATION, AND EXPLORING THE POTENTIAL OF
USING THE BRICHOS DOMAIN IN THE FIGHT AGAINST ALZEIMER S DISEASE AND
OTHER AMYLOID DISEASES SEEMS HIGHLY RELEVANT. THIS BRIEF IS USEFUL FOR
NEWCOMERS TO THIS FIELD OR RESEARCHERS IN RELATED FIELDS WISHING TO GAIN
A QUICK OVERVIEW OF THE LATEST FINDINGS
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
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| dewey-ones | 547 - Organic chemistry |
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| dewey-search | 547 |
| dewey-sort | 3547 |
| dewey-tens | 540 - Chemistry and allied sciences |
| discipline | Chemie / Pharmazie |
| doi_str_mv | 10.1007/978-3-319-16564-6 |
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| id | DE-604.BV042481939 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:23:00Z |
| institution | BVB |
| isbn | 9783319165646 |
| issn | 2191-5407 |
| language | English |
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| spelling | Presto, Jenny Verfasser aut The BRICHOS Domain Its Proproteins and Functions Jenny Presto, Jan Johansson Cham [u.a.] Springer International Publishing 2015 1 Online-Ressource (XV, 28 p. 13 illus. in color) txt rdacontent c rdamedia cr rdacarrier SpringerBriefs in Molecular Science 2191-5407 Chemistry Bioorganic chemistry Biochemistry Bioorganic Chemistry Protein Structure Chemie Johansson, Jan Verfasser aut Erscheint auch als Druckausgabe 978-3-319-16563-9 https://doi.org/10.1007/978-3-319-16564-6 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027916898&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027916898&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Presto, Jenny Johansson, Jan The BRICHOS Domain Its Proproteins and Functions Chemistry Bioorganic chemistry Biochemistry Bioorganic Chemistry Protein Structure Chemie |
| title | The BRICHOS Domain Its Proproteins and Functions |
| title_auth | The BRICHOS Domain Its Proproteins and Functions |
| title_exact_search | The BRICHOS Domain Its Proproteins and Functions |
| title_full | The BRICHOS Domain Its Proproteins and Functions Jenny Presto, Jan Johansson |
| title_fullStr | The BRICHOS Domain Its Proproteins and Functions Jenny Presto, Jan Johansson |
| title_full_unstemmed | The BRICHOS Domain Its Proproteins and Functions Jenny Presto, Jan Johansson |
| title_short | The BRICHOS Domain |
| title_sort | the brichos domain its proproteins and functions |
| title_sub | Its Proproteins and Functions |
| topic | Chemistry Bioorganic chemistry Biochemistry Bioorganic Chemistry Protein Structure Chemie |
| topic_facet | Chemistry Bioorganic chemistry Biochemistry Bioorganic Chemistry Protein Structure Chemie |
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