Glutamate and Addiction:
The past decade has witnessed a growing body of preclinical and clinical evidence that glutamatergic systems may play a pivotal role in drug dependence. In Glutamate and Addiction, world-renowned scientific experts critically review all of this evidence and make the case for the role of glutamatergi...
Gespeichert in:
| Weitere Verfasser: | , , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2002
|
| Schriftenreihe: | Contemporary Clinical Neuroscience
|
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | The past decade has witnessed a growing body of preclinical and clinical evidence that glutamatergic systems may play a pivotal role in drug dependence. In Glutamate and Addiction, world-renowned scientific experts critically review all of this evidence and make the case for the role of glutamatergic systems in both the etiology and treatment of addiction disorders. The authors examine the glutamate connection in stimulant drugs of abuse (cocaine, amphetamine, and methamphetamine), in opiate addiction, and in alcohol abuse and dependence. Using a variety of pharmacological, biochemical, genetic, and brain imaging techniques, these investigators show precisely how glutamate is involved in the etiology of addictions and how blocking or activating certain elements of the glutamatergic system appear to alleviate particular components of addiction. Their survey takes in both clinical approaches using medications that influence glutamate and cutting-edge preclinical approaches that manipulate specific subtypes of glutamate receptors or specific substrates of the "glutamate cascade" to determine their roles in various addictive states. The discussion includes a full review of possible treatments of addiction using glutamatergic antagonists and co-agonists such as acamprosate to modify specific aspects of glutamate function in the central nervous system. Illuminating, authoritative, and forward looking, Glutamate and Addiction clarifies for the first time the relationship between glutamatergic systems and addiction and sets the stage for productive experimental and clinical investigations of many of today's emerging therapeutics for addictive disorders |
| Beschreibung: | 1 Online-Ressource (XVIII, 440 p) |
| ISBN: | 9781592593064 |
| DOI: | 10.1007/978-1-59259-306-4 |
Internformat
MARC
| LEADER | 00000nmm a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV046149097 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 190906s2002 |||| o||u| ||||||eng d | ||
| 020 | |a 9781592593064 |9 978-1-59259-306-4 | ||
| 024 | 7 | |a 10.1007/978-1-59259-306-4 |2 doi | |
| 035 | |a (ZDB-2-SBL)978-1-59259-306-4 | ||
| 035 | |a (OCoLC)1119028402 | ||
| 035 | |a (DE-599)BVBBV046149097 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 | ||
| 082 | 0 | |a 615 |2 23 | |
| 245 | 1 | 0 | |a Glutamate and Addiction |c edited by Barbara H. Herman, Jerry Frankenheim, Raye Z. Litten, Philip H. Sheridan, Forrest F. Weight, Steven R. Zukin |
| 264 | 1 | |a Totowa, NJ |b Humana Press |c 2002 | |
| 300 | |a 1 Online-Ressource (XVIII, 440 p) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 490 | 0 | |a Contemporary Clinical Neuroscience | |
| 520 | |a The past decade has witnessed a growing body of preclinical and clinical evidence that glutamatergic systems may play a pivotal role in drug dependence. In Glutamate and Addiction, world-renowned scientific experts critically review all of this evidence and make the case for the role of glutamatergic systems in both the etiology and treatment of addiction disorders. The authors examine the glutamate connection in stimulant drugs of abuse (cocaine, amphetamine, and methamphetamine), in opiate addiction, and in alcohol abuse and dependence. Using a variety of pharmacological, biochemical, genetic, and brain imaging techniques, these investigators show precisely how glutamate is involved in the etiology of addictions and how blocking or activating certain elements of the glutamatergic system appear to alleviate particular components of addiction. Their survey takes in both clinical approaches using medications that influence glutamate and cutting-edge preclinical approaches that manipulate specific subtypes of glutamate receptors or specific substrates of the "glutamate cascade" to determine their roles in various addictive states. The discussion includes a full review of possible treatments of addiction using glutamatergic antagonists and co-agonists such as acamprosate to modify specific aspects of glutamate function in the central nervous system. Illuminating, authoritative, and forward looking, Glutamate and Addiction clarifies for the first time the relationship between glutamatergic systems and addiction and sets the stage for productive experimental and clinical investigations of many of today's emerging therapeutics for addictive disorders | ||
| 650 | 4 | |a Pharmacology/Toxicology | |
| 650 | 4 | |a Neurosciences | |
| 650 | 4 | |a Toxicology | |
| 650 | 4 | |a Neurosciences | |
| 700 | 1 | |a Herman, Barbara H. |4 edt | |
| 700 | 1 | |a Frankenheim, Jerry |4 edt | |
| 700 | 1 | |a Litten, Raye Z. |4 edt | |
| 700 | 1 | |a Sheridan, Philip H. |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781617372346 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9780896038790 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781468497298 |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-1-59259-306-4 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
| 912 | |a ZDB-2-SBL | ||
| 940 | 1 | |q ZDB-2-SBL_2000/2004 | |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-031529274 | ||
| 966 | e | |u https://doi.org/10.1007/978-1-59259-306-4 |l UBR01 |p ZDB-2-SBL |q ZDB-2-SBL_2000/2004 |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804180490190585856 |
|---|---|
| any_adam_object | |
| author2 | Herman, Barbara H. Frankenheim, Jerry Litten, Raye Z. Sheridan, Philip H. |
| author2_role | edt edt edt edt |
| author2_variant | b h h bh bhh j f jf r z l rz rzl p h s ph phs |
| author_facet | Herman, Barbara H. Frankenheim, Jerry Litten, Raye Z. Sheridan, Philip H. |
| building | Verbundindex |
| bvnumber | BV046149097 |
| collection | ZDB-2-SBL |
| ctrlnum | (ZDB-2-SBL)978-1-59259-306-4 (OCoLC)1119028402 (DE-599)BVBBV046149097 |
| dewey-full | 615 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615 |
| dewey-search | 615 |
| dewey-sort | 3615 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-59259-306-4 |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03398nmm a2200481zc 4500</leader><controlfield tag="001">BV046149097</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">190906s2002 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781592593064</subfield><subfield code="9">978-1-59259-306-4</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/978-1-59259-306-4</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-2-SBL)978-1-59259-306-4</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1119028402</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV046149097</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">615</subfield><subfield code="2">23</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Glutamate and Addiction</subfield><subfield code="c">edited by Barbara H. Herman, Jerry Frankenheim, Raye Z. Litten, Philip H. Sheridan, Forrest F. Weight, Steven R. Zukin</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Totowa, NJ</subfield><subfield code="b">Humana Press</subfield><subfield code="c">2002</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (XVIII, 440 p)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Contemporary Clinical Neuroscience</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The past decade has witnessed a growing body of preclinical and clinical evidence that glutamatergic systems may play a pivotal role in drug dependence. In Glutamate and Addiction, world-renowned scientific experts critically review all of this evidence and make the case for the role of glutamatergic systems in both the etiology and treatment of addiction disorders. The authors examine the glutamate connection in stimulant drugs of abuse (cocaine, amphetamine, and methamphetamine), in opiate addiction, and in alcohol abuse and dependence. Using a variety of pharmacological, biochemical, genetic, and brain imaging techniques, these investigators show precisely how glutamate is involved in the etiology of addictions and how blocking or activating certain elements of the glutamatergic system appear to alleviate particular components of addiction. Their survey takes in both clinical approaches using medications that influence glutamate and cutting-edge preclinical approaches that manipulate specific subtypes of glutamate receptors or specific substrates of the "glutamate cascade" to determine their roles in various addictive states. The discussion includes a full review of possible treatments of addiction using glutamatergic antagonists and co-agonists such as acamprosate to modify specific aspects of glutamate function in the central nervous system. Illuminating, authoritative, and forward looking, Glutamate and Addiction clarifies for the first time the relationship between glutamatergic systems and addiction and sets the stage for productive experimental and clinical investigations of many of today's emerging therapeutics for addictive disorders</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacology/Toxicology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Neurosciences</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Toxicology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Neurosciences</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Herman, Barbara H.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Frankenheim, Jerry</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Litten, Raye Z.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sheridan, Philip H.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781617372346</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9780896038790</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781468497298</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1007/978-1-59259-306-4</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-SBL</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">ZDB-2-SBL_2000/2004</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-031529274</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-59259-306-4</subfield><subfield code="l">UBR01</subfield><subfield code="p">ZDB-2-SBL</subfield><subfield code="q">ZDB-2-SBL_2000/2004</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| id | DE-604.BV046149097 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:35Z |
| institution | BVB |
| isbn | 9781592593064 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-031529274 |
| oclc_num | 1119028402 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR |
| owner_facet | DE-355 DE-BY-UBR |
| physical | 1 Online-Ressource (XVIII, 440 p) |
| psigel | ZDB-2-SBL ZDB-2-SBL_2000/2004 ZDB-2-SBL ZDB-2-SBL_2000/2004 |
| publishDate | 2002 |
| publishDateSearch | 2002 |
| publishDateSort | 2002 |
| publisher | Humana Press |
| record_format | marc |
| series2 | Contemporary Clinical Neuroscience |
| spelling | Glutamate and Addiction edited by Barbara H. Herman, Jerry Frankenheim, Raye Z. Litten, Philip H. Sheridan, Forrest F. Weight, Steven R. Zukin Totowa, NJ Humana Press 2002 1 Online-Ressource (XVIII, 440 p) txt rdacontent c rdamedia cr rdacarrier Contemporary Clinical Neuroscience The past decade has witnessed a growing body of preclinical and clinical evidence that glutamatergic systems may play a pivotal role in drug dependence. In Glutamate and Addiction, world-renowned scientific experts critically review all of this evidence and make the case for the role of glutamatergic systems in both the etiology and treatment of addiction disorders. The authors examine the glutamate connection in stimulant drugs of abuse (cocaine, amphetamine, and methamphetamine), in opiate addiction, and in alcohol abuse and dependence. Using a variety of pharmacological, biochemical, genetic, and brain imaging techniques, these investigators show precisely how glutamate is involved in the etiology of addictions and how blocking or activating certain elements of the glutamatergic system appear to alleviate particular components of addiction. Their survey takes in both clinical approaches using medications that influence glutamate and cutting-edge preclinical approaches that manipulate specific subtypes of glutamate receptors or specific substrates of the "glutamate cascade" to determine their roles in various addictive states. The discussion includes a full review of possible treatments of addiction using glutamatergic antagonists and co-agonists such as acamprosate to modify specific aspects of glutamate function in the central nervous system. Illuminating, authoritative, and forward looking, Glutamate and Addiction clarifies for the first time the relationship between glutamatergic systems and addiction and sets the stage for productive experimental and clinical investigations of many of today's emerging therapeutics for addictive disorders Pharmacology/Toxicology Neurosciences Toxicology Herman, Barbara H. edt Frankenheim, Jerry edt Litten, Raye Z. edt Sheridan, Philip H. edt Erscheint auch als Druck-Ausgabe 9781617372346 Erscheint auch als Druck-Ausgabe 9780896038790 Erscheint auch als Druck-Ausgabe 9781468497298 https://doi.org/10.1007/978-1-59259-306-4 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Glutamate and Addiction Pharmacology/Toxicology Neurosciences Toxicology |
| title | Glutamate and Addiction |
| title_auth | Glutamate and Addiction |
| title_exact_search | Glutamate and Addiction |
| title_full | Glutamate and Addiction edited by Barbara H. Herman, Jerry Frankenheim, Raye Z. Litten, Philip H. Sheridan, Forrest F. Weight, Steven R. Zukin |
| title_fullStr | Glutamate and Addiction edited by Barbara H. Herman, Jerry Frankenheim, Raye Z. Litten, Philip H. Sheridan, Forrest F. Weight, Steven R. Zukin |
| title_full_unstemmed | Glutamate and Addiction edited by Barbara H. Herman, Jerry Frankenheim, Raye Z. Litten, Philip H. Sheridan, Forrest F. Weight, Steven R. Zukin |
| title_short | Glutamate and Addiction |
| title_sort | glutamate and addiction |
| topic | Pharmacology/Toxicology Neurosciences Toxicology |
| topic_facet | Pharmacology/Toxicology Neurosciences Toxicology |
| url | https://doi.org/10.1007/978-1-59259-306-4 |
| work_keys_str_mv | AT hermanbarbarah glutamateandaddiction AT frankenheimjerry glutamateandaddiction AT littenrayez glutamateandaddiction AT sheridanphiliph glutamateandaddiction |