Extracellular vesicles :: applications to regenerative medicine, therapeutics and diagnostics /
With the development of stem cell engineering, extrcellular vesicles promise to deliver next generation tools in regenerative medicine and tissue engineering, as well as in diagnostics. A vibrant and promising field, this book provides the first resource to the field.
Gespeichert in:
| Weitere Verfasser: | , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
London :
Royal Society of Chemistry,
[2022]
|
| Schriftenreihe: | Biomaterials science series ;
9. |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | With the development of stem cell engineering, extrcellular vesicles promise to deliver next generation tools in regenerative medicine and tissue engineering, as well as in diagnostics. A vibrant and promising field, this book provides the first resource to the field. |
| Beschreibung: | 1 online resource |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9781839164569 1839164565 9781839164552 1839164557 |
Internformat
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| 520 | |a With the development of stem cell engineering, extrcellular vesicles promise to deliver next generation tools in regenerative medicine and tissue engineering, as well as in diagnostics. A vibrant and promising field, this book provides the first resource to the field. | ||
| 588 | 0 | |a Online resource; title from digital title page (viewed on November 29, 2021). | |
| 505 | 0 | |a Intro -- Half Title -- Series Editors -- Title -- Copyright -- Preface -- Contents -- Chapter 1 Therapeutic Potential of Mesenchymal Stromal Cell-derived Small Extracellular Vesicles -- 1.1 Concepts in Regenerative Medicine -- 1.2 MSCs Act in a Paracrine Rather than Cellular Manner -- 1.3 MSC-EVs Mediate Their Therapeutic Effects via Extracellular Vesicles -- 1.4 MSC-sEVs Improve Disease Symptoms in Many Different Disease Models -- 1.5 MSC-sEVs Have Successfully Been Applied to Patients -- 1.6 Immunomodulatory Activities of MSC-EV Products -- 1.7 Other Activities Mediated by MSC-EV Products | |
| 505 | 8 | |a 1.8 Heterogeneity of MSC-sEV Preparations -- 1.9 Take-home Message -- References -- Chapter 2 Separation and Purification of Extracellular and Bio-fluid Vesicles -- State of the Art: Past, Present, and Future of Extracellular Vesicle Separation and Purification -- 2.1 Introduction -- 2.2 EV Separation Methods -- 2.2.1 Density-based Separation -- 2.2.2 Size-based Separation -- 2.2.3 Affinity (AFF) -- 2.2.4 Precipitation (PPT) -- 2.3 Comparative Evaluation of EV Separation Methods -- 2.4 Combination of Methods for EV Separation -- 2.5 Emerging Technologies -- 2.6 Conclusions and Future Perspectives | |
| 505 | 8 | |a Chapter 4 Biological Characterization of Extracellular Vesicles -- Methodologies to Characterize Molecular Composition of Extracellular Vesicles -- Advances Towards Single Vesicle Characterization -- 4.1 Introduction -- 4.2 The Demand for Single Vesicle Characterization Methods -- 4.3 Imaging Methods -- 4.4 Light Microscopy -- 4.4.1 Widefield Fluorescence Microscopy -- 4.4.2 Confocal Microscopy -- 4.4.3 Super-resolution Techniques -- 4.4.4 Fluorescence Correlation Spectroscopy (FCS) -- 4.5 Electron Microscopy -- 4.5.1 Transmission Electron Microscopy (TEM) -- 4.5.2 Cryo-electron Microscopy | |
| 505 | 8 | |a 4.5.3 Scanning Electron Microscopy (SEM) -- 4.5.4 Immunoelectron Microscopy (iEM) -- 4.5.5 Correlative Imaging Techniques -- 4.5.6 Flow Cytometry -- 4.5.7 Label-free Techniques -- 4.6 Detection of Specific Molecules in EVs by Labeling Methods for Light Microscopy -- 4.6.1 Labeling Methods for EVs -- 4.6.2 Lipid Stains in EV Detection -- 4.6.3 Proteins -- 4.6.4 Live Cell (EV) Imaging by Light Microscopy -- 4.6.5 Analysis of Carbohydrates -- 4.7 Future Challenges and Opportunities -- References -- Chapter 5 Extracellular Vesicles in Bone Tissue Engineering -- 5.1 Introduction | |
| 650 | 0 | |a Extracellular matrix. |0 http://id.loc.gov/authorities/subjects/sh85057464 | |
| 650 | 0 | |a Liposomes. |0 http://id.loc.gov/authorities/subjects/sh85077311 | |
| 650 | 2 | |a Extracellular Matrix |0 https://id.nlm.nih.gov/mesh/D005109 | |
| 650 | 2 | |a Liposomes |0 https://id.nlm.nih.gov/mesh/D008081 | |
| 650 | 6 | |a Substance fondamentale (Histologie) | |
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| 650 | 7 | |a Extracellular matrix |2 fast | |
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| 700 | 1 | |a Lim, C. T., |e editor. |0 http://id.loc.gov/authorities/names/nr97018198 | |
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| contents | Intro -- Half Title -- Series Editors -- Title -- Copyright -- Preface -- Contents -- Chapter 1 Therapeutic Potential of Mesenchymal Stromal Cell-derived Small Extracellular Vesicles -- 1.1 Concepts in Regenerative Medicine -- 1.2 MSCs Act in a Paracrine Rather than Cellular Manner -- 1.3 MSC-EVs Mediate Their Therapeutic Effects via Extracellular Vesicles -- 1.4 MSC-sEVs Improve Disease Symptoms in Many Different Disease Models -- 1.5 MSC-sEVs Have Successfully Been Applied to Patients -- 1.6 Immunomodulatory Activities of MSC-EV Products -- 1.7 Other Activities Mediated by MSC-EV Products 1.8 Heterogeneity of MSC-sEV Preparations -- 1.9 Take-home Message -- References -- Chapter 2 Separation and Purification of Extracellular and Bio-fluid Vesicles -- State of the Art: Past, Present, and Future of Extracellular Vesicle Separation and Purification -- 2.1 Introduction -- 2.2 EV Separation Methods -- 2.2.1 Density-based Separation -- 2.2.2 Size-based Separation -- 2.2.3 Affinity (AFF) -- 2.2.4 Precipitation (PPT) -- 2.3 Comparative Evaluation of EV Separation Methods -- 2.4 Combination of Methods for EV Separation -- 2.5 Emerging Technologies -- 2.6 Conclusions and Future Perspectives Chapter 4 Biological Characterization of Extracellular Vesicles -- Methodologies to Characterize Molecular Composition of Extracellular Vesicles -- Advances Towards Single Vesicle Characterization -- 4.1 Introduction -- 4.2 The Demand for Single Vesicle Characterization Methods -- 4.3 Imaging Methods -- 4.4 Light Microscopy -- 4.4.1 Widefield Fluorescence Microscopy -- 4.4.2 Confocal Microscopy -- 4.4.3 Super-resolution Techniques -- 4.4.4 Fluorescence Correlation Spectroscopy (FCS) -- 4.5 Electron Microscopy -- 4.5.1 Transmission Electron Microscopy (TEM) -- 4.5.2 Cryo-electron Microscopy 4.5.3 Scanning Electron Microscopy (SEM) -- 4.5.4 Immunoelectron Microscopy (iEM) -- 4.5.5 Correlative Imaging Techniques -- 4.5.6 Flow Cytometry -- 4.5.7 Label-free Techniques -- 4.6 Detection of Specific Molecules in EVs by Labeling Methods for Light Microscopy -- 4.6.1 Labeling Methods for EVs -- 4.6.2 Lipid Stains in EV Detection -- 4.6.3 Proteins -- 4.6.4 Live Cell (EV) Imaging by Light Microscopy -- 4.6.5 Analysis of Carbohydrates -- 4.7 Future Challenges and Opportunities -- References -- Chapter 5 Extracellular Vesicles in Bone Tissue Engineering -- 5.1 Introduction |
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| illustrated | Illustrated |
| indexdate | 2024-11-27T13:30:25Z |
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| isbn | 9781839164569 1839164565 9781839164552 1839164557 |
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| series | Biomaterials science series ; |
| series2 | Biomaterials science series ; |
| spelling | Extracellular vesicles : applications to regenerative medicine, therapeutics and diagnostics / edited by Wojciech Chrzanowski, Chwee Teck Lim and Sally Yunsun Kim. London : Royal Society of Chemistry, [2022] 1 online resource text txt rdacontent computer c rdamedia online resource cr rdacarrier Biomaterials science series ; 9 Includes bibliographical references and index. With the development of stem cell engineering, extrcellular vesicles promise to deliver next generation tools in regenerative medicine and tissue engineering, as well as in diagnostics. A vibrant and promising field, this book provides the first resource to the field. Online resource; title from digital title page (viewed on November 29, 2021). Intro -- Half Title -- Series Editors -- Title -- Copyright -- Preface -- Contents -- Chapter 1 Therapeutic Potential of Mesenchymal Stromal Cell-derived Small Extracellular Vesicles -- 1.1 Concepts in Regenerative Medicine -- 1.2 MSCs Act in a Paracrine Rather than Cellular Manner -- 1.3 MSC-EVs Mediate Their Therapeutic Effects via Extracellular Vesicles -- 1.4 MSC-sEVs Improve Disease Symptoms in Many Different Disease Models -- 1.5 MSC-sEVs Have Successfully Been Applied to Patients -- 1.6 Immunomodulatory Activities of MSC-EV Products -- 1.7 Other Activities Mediated by MSC-EV Products 1.8 Heterogeneity of MSC-sEV Preparations -- 1.9 Take-home Message -- References -- Chapter 2 Separation and Purification of Extracellular and Bio-fluid Vesicles -- State of the Art: Past, Present, and Future of Extracellular Vesicle Separation and Purification -- 2.1 Introduction -- 2.2 EV Separation Methods -- 2.2.1 Density-based Separation -- 2.2.2 Size-based Separation -- 2.2.3 Affinity (AFF) -- 2.2.4 Precipitation (PPT) -- 2.3 Comparative Evaluation of EV Separation Methods -- 2.4 Combination of Methods for EV Separation -- 2.5 Emerging Technologies -- 2.6 Conclusions and Future Perspectives Chapter 4 Biological Characterization of Extracellular Vesicles -- Methodologies to Characterize Molecular Composition of Extracellular Vesicles -- Advances Towards Single Vesicle Characterization -- 4.1 Introduction -- 4.2 The Demand for Single Vesicle Characterization Methods -- 4.3 Imaging Methods -- 4.4 Light Microscopy -- 4.4.1 Widefield Fluorescence Microscopy -- 4.4.2 Confocal Microscopy -- 4.4.3 Super-resolution Techniques -- 4.4.4 Fluorescence Correlation Spectroscopy (FCS) -- 4.5 Electron Microscopy -- 4.5.1 Transmission Electron Microscopy (TEM) -- 4.5.2 Cryo-electron Microscopy 4.5.3 Scanning Electron Microscopy (SEM) -- 4.5.4 Immunoelectron Microscopy (iEM) -- 4.5.5 Correlative Imaging Techniques -- 4.5.6 Flow Cytometry -- 4.5.7 Label-free Techniques -- 4.6 Detection of Specific Molecules in EVs by Labeling Methods for Light Microscopy -- 4.6.1 Labeling Methods for EVs -- 4.6.2 Lipid Stains in EV Detection -- 4.6.3 Proteins -- 4.6.4 Live Cell (EV) Imaging by Light Microscopy -- 4.6.5 Analysis of Carbohydrates -- 4.7 Future Challenges and Opportunities -- References -- Chapter 5 Extracellular Vesicles in Bone Tissue Engineering -- 5.1 Introduction Extracellular matrix. http://id.loc.gov/authorities/subjects/sh85057464 Liposomes. http://id.loc.gov/authorities/subjects/sh85077311 Extracellular Matrix https://id.nlm.nih.gov/mesh/D005109 Liposomes https://id.nlm.nih.gov/mesh/D008081 Substance fondamentale (Histologie) Liposomes. Extracellular matrix fast Liposomes fast Chrzanowski, Wojciech (Senior lecturer, pharmaceutics), editor. https://id.oclc.org/worldcat/entity/E39PCjBwMFXcRW3vgXYd7rV3cP http://id.loc.gov/authorities/names/nb2014029213 Lim, C. T., editor. http://id.loc.gov/authorities/names/nr97018198 Kim, Sally Yunsun, editor. has work: Extracellular vesicles (Text) https://id.oclc.org/worldcat/entity/E39PCFYfqJvTrY6qVkqDyDHY8y https://id.oclc.org/worldcat/ontology/hasWork Print version: 178801894X 9781788018944 (OCoLC)1237634298 Biomaterials science series ; 9. http://id.loc.gov/authorities/names/n2019180558 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3068011 Volltext |
| spellingShingle | Extracellular vesicles : applications to regenerative medicine, therapeutics and diagnostics / Biomaterials science series ; Intro -- Half Title -- Series Editors -- Title -- Copyright -- Preface -- Contents -- Chapter 1 Therapeutic Potential of Mesenchymal Stromal Cell-derived Small Extracellular Vesicles -- 1.1 Concepts in Regenerative Medicine -- 1.2 MSCs Act in a Paracrine Rather than Cellular Manner -- 1.3 MSC-EVs Mediate Their Therapeutic Effects via Extracellular Vesicles -- 1.4 MSC-sEVs Improve Disease Symptoms in Many Different Disease Models -- 1.5 MSC-sEVs Have Successfully Been Applied to Patients -- 1.6 Immunomodulatory Activities of MSC-EV Products -- 1.7 Other Activities Mediated by MSC-EV Products 1.8 Heterogeneity of MSC-sEV Preparations -- 1.9 Take-home Message -- References -- Chapter 2 Separation and Purification of Extracellular and Bio-fluid Vesicles -- State of the Art: Past, Present, and Future of Extracellular Vesicle Separation and Purification -- 2.1 Introduction -- 2.2 EV Separation Methods -- 2.2.1 Density-based Separation -- 2.2.2 Size-based Separation -- 2.2.3 Affinity (AFF) -- 2.2.4 Precipitation (PPT) -- 2.3 Comparative Evaluation of EV Separation Methods -- 2.4 Combination of Methods for EV Separation -- 2.5 Emerging Technologies -- 2.6 Conclusions and Future Perspectives Chapter 4 Biological Characterization of Extracellular Vesicles -- Methodologies to Characterize Molecular Composition of Extracellular Vesicles -- Advances Towards Single Vesicle Characterization -- 4.1 Introduction -- 4.2 The Demand for Single Vesicle Characterization Methods -- 4.3 Imaging Methods -- 4.4 Light Microscopy -- 4.4.1 Widefield Fluorescence Microscopy -- 4.4.2 Confocal Microscopy -- 4.4.3 Super-resolution Techniques -- 4.4.4 Fluorescence Correlation Spectroscopy (FCS) -- 4.5 Electron Microscopy -- 4.5.1 Transmission Electron Microscopy (TEM) -- 4.5.2 Cryo-electron Microscopy 4.5.3 Scanning Electron Microscopy (SEM) -- 4.5.4 Immunoelectron Microscopy (iEM) -- 4.5.5 Correlative Imaging Techniques -- 4.5.6 Flow Cytometry -- 4.5.7 Label-free Techniques -- 4.6 Detection of Specific Molecules in EVs by Labeling Methods for Light Microscopy -- 4.6.1 Labeling Methods for EVs -- 4.6.2 Lipid Stains in EV Detection -- 4.6.3 Proteins -- 4.6.4 Live Cell (EV) Imaging by Light Microscopy -- 4.6.5 Analysis of Carbohydrates -- 4.7 Future Challenges and Opportunities -- References -- Chapter 5 Extracellular Vesicles in Bone Tissue Engineering -- 5.1 Introduction Extracellular matrix. http://id.loc.gov/authorities/subjects/sh85057464 Liposomes. http://id.loc.gov/authorities/subjects/sh85077311 Extracellular Matrix https://id.nlm.nih.gov/mesh/D005109 Liposomes https://id.nlm.nih.gov/mesh/D008081 Substance fondamentale (Histologie) Liposomes. Extracellular matrix fast Liposomes fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85057464 http://id.loc.gov/authorities/subjects/sh85077311 https://id.nlm.nih.gov/mesh/D005109 https://id.nlm.nih.gov/mesh/D008081 |
| title | Extracellular vesicles : applications to regenerative medicine, therapeutics and diagnostics / |
| title_auth | Extracellular vesicles : applications to regenerative medicine, therapeutics and diagnostics / |
| title_exact_search | Extracellular vesicles : applications to regenerative medicine, therapeutics and diagnostics / |
| title_full | Extracellular vesicles : applications to regenerative medicine, therapeutics and diagnostics / edited by Wojciech Chrzanowski, Chwee Teck Lim and Sally Yunsun Kim. |
| title_fullStr | Extracellular vesicles : applications to regenerative medicine, therapeutics and diagnostics / edited by Wojciech Chrzanowski, Chwee Teck Lim and Sally Yunsun Kim. |
| title_full_unstemmed | Extracellular vesicles : applications to regenerative medicine, therapeutics and diagnostics / edited by Wojciech Chrzanowski, Chwee Teck Lim and Sally Yunsun Kim. |
| title_short | Extracellular vesicles : |
| title_sort | extracellular vesicles applications to regenerative medicine therapeutics and diagnostics |
| title_sub | applications to regenerative medicine, therapeutics and diagnostics / |
| topic | Extracellular matrix. http://id.loc.gov/authorities/subjects/sh85057464 Liposomes. http://id.loc.gov/authorities/subjects/sh85077311 Extracellular Matrix https://id.nlm.nih.gov/mesh/D005109 Liposomes https://id.nlm.nih.gov/mesh/D008081 Substance fondamentale (Histologie) Liposomes. Extracellular matrix fast Liposomes fast |
| topic_facet | Extracellular matrix. Liposomes. Extracellular Matrix Liposomes Substance fondamentale (Histologie) Extracellular matrix |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3068011 |
| work_keys_str_mv | AT chrzanowskiwojciech extracellularvesiclesapplicationstoregenerativemedicinetherapeuticsanddiagnostics AT limct extracellularvesiclesapplicationstoregenerativemedicinetherapeuticsanddiagnostics AT kimsallyyunsun extracellularvesiclesapplicationstoregenerativemedicinetherapeuticsanddiagnostics |