New Perspectives in Molecular and Clinical Management of Gastrointestinal Tumors:
This volume focuses on new and exciting approaches in the molecular and clinical management of gastrointestinal tumors. The first part presents recent insights into carcinogenesis, including alterations in cyclins and adhesion receptors, molecular structures which might be new targets of gene therap...
Gespeichert in:
Weitere Verfasser: | , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
1996
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Schriftenreihe: | Recent Results in Cancer Research
142 |
Schlagworte: | |
Online-Zugang: | UBR01 Volltext |
Zusammenfassung: | This volume focuses on new and exciting approaches in the molecular and clinical management of gastrointestinal tumors. The first part presents recent insights into carcinogenesis, including alterations in cyclins and adhesion receptors, molecular structures which might be new targets of gene therapy. The second part of the volume offers new diagnostic tools, such as receptors for gastrointestinal hormones, proliferation markers, tumor suppressor proteins, and the multiple drug resistance gene, predicting response to therapy and prognosis in gastrointestinal tumors. The third part gives an update of successful approaches in primary and secondary prevention of colorectal carcinoma. Nutritional factors and pharmacologic agents can clearly decrease the risk, and fecal occult blood tests and endoscopy can reduce the mortality in colorectal carcinoma. Laparoscopic staging with subsequent biopsy of suspicious lymph nodes provides essential information in esophageal and gastric cancer. In locally advanced gastric cancer, preoperative chemotherapy provides sufficient evidence to investigate this approach as compared to primary surgery. Standards have recently been established in the adjuvant treatment of patients with gastrointestinal carcinoma, and promising new drugs, including monoclonal antibodies, thymidylate synthase, and topoisomerase inhibitors, as well as taxoids, are currently being tested in phase I, II, and III trials of gastrointestinal tumors |
Beschreibung: | 1 Online-Ressource (XII, 439 p. 9 illus. in color) |
ISBN: | 9783642800351 |
DOI: | 10.1007/978-3-642-80035-1 |
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520 | |a This volume focuses on new and exciting approaches in the molecular and clinical management of gastrointestinal tumors. The first part presents recent insights into carcinogenesis, including alterations in cyclins and adhesion receptors, molecular structures which might be new targets of gene therapy. The second part of the volume offers new diagnostic tools, such as receptors for gastrointestinal hormones, proliferation markers, tumor suppressor proteins, and the multiple drug resistance gene, predicting response to therapy and prognosis in gastrointestinal tumors. The third part gives an update of successful approaches in primary and secondary prevention of colorectal carcinoma. Nutritional factors and pharmacologic agents can clearly decrease the risk, and fecal occult blood tests and endoscopy can reduce the mortality in colorectal carcinoma. Laparoscopic staging with subsequent biopsy of suspicious lymph nodes provides essential information in esophageal and gastric cancer. In locally advanced gastric cancer, preoperative chemotherapy provides sufficient evidence to investigate this approach as compared to primary surgery. Standards have recently been established in the adjuvant treatment of patients with gastrointestinal carcinoma, and promising new drugs, including monoclonal antibodies, thymidylate synthase, and topoisomerase inhibitors, as well as taxoids, are currently being tested in phase I, II, and III trials of gastrointestinal tumors | ||
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Datensatz im Suchindex
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any_adam_object | |
author2 | Kreuser, Ernst-D Schlag, P. M. |
author2_role | edt edt |
author2_variant | e d k edk p m s pm pms |
author_facet | Kreuser, Ernst-D Schlag, P. M. |
building | Verbundindex |
bvnumber | BV046144590 |
classification_rvk | XH 6600 XH 7100 |
collection | ZDB-2-SME |
ctrlnum | (ZDB-2-SME)978-3-642-80035-1 (OCoLC)1118979673 (DE-599)BVBBV046144590 |
dewey-full | 616.994 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 616 - Diseases |
dewey-raw | 616.994 |
dewey-search | 616.994 |
dewey-sort | 3616.994 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
doi_str_mv | 10.1007/978-3-642-80035-1 |
format | Electronic eBook |
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institution | BVB |
isbn | 9783642800351 |
language | English |
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physical | 1 Online-Ressource (XII, 439 p. 9 illus. in color) |
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publisher | Springer Berlin Heidelberg |
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spelling | New Perspectives in Molecular and Clinical Management of Gastrointestinal Tumors edited by Ernst-D. Kreuser, P. M. Schlag Berlin, Heidelberg Springer Berlin Heidelberg 1996 1 Online-Ressource (XII, 439 p. 9 illus. in color) txt rdacontent c rdamedia cr rdacarrier Recent Results in Cancer Research 142 This volume focuses on new and exciting approaches in the molecular and clinical management of gastrointestinal tumors. The first part presents recent insights into carcinogenesis, including alterations in cyclins and adhesion receptors, molecular structures which might be new targets of gene therapy. The second part of the volume offers new diagnostic tools, such as receptors for gastrointestinal hormones, proliferation markers, tumor suppressor proteins, and the multiple drug resistance gene, predicting response to therapy and prognosis in gastrointestinal tumors. The third part gives an update of successful approaches in primary and secondary prevention of colorectal carcinoma. Nutritional factors and pharmacologic agents can clearly decrease the risk, and fecal occult blood tests and endoscopy can reduce the mortality in colorectal carcinoma. Laparoscopic staging with subsequent biopsy of suspicious lymph nodes provides essential information in esophageal and gastric cancer. In locally advanced gastric cancer, preoperative chemotherapy provides sufficient evidence to investigate this approach as compared to primary surgery. Standards have recently been established in the adjuvant treatment of patients with gastrointestinal carcinoma, and promising new drugs, including monoclonal antibodies, thymidylate synthase, and topoisomerase inhibitors, as well as taxoids, are currently being tested in phase I, II, and III trials of gastrointestinal tumors Oncology Abdominal Surgery Imaging / Radiology Oncology Abdomen / Surgery Radiology, Medical Molekularpathologie (DE-588)4170396-0 gnd rswk-swf Gastrointestinaler Tumor (DE-588)4224415-8 gnd rswk-swf Therapie (DE-588)4059798-2 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Gastrointestinaler Tumor (DE-588)4224415-8 s Molekularpathologie (DE-588)4170396-0 s DE-604 Molekularbiologie (DE-588)4039983-7 s Therapie (DE-588)4059798-2 s Kreuser, Ernst-D. edt Schlag, P. M. edt Erscheint auch als Druck-Ausgabe 9783642800375 Erscheint auch als Druck-Ausgabe 9783540604983 Erscheint auch als Druck-Ausgabe 9783642800368 https://doi.org/10.1007/978-3-642-80035-1 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | New Perspectives in Molecular and Clinical Management of Gastrointestinal Tumors Oncology Abdominal Surgery Imaging / Radiology Oncology Abdomen / Surgery Radiology, Medical Molekularpathologie (DE-588)4170396-0 gnd Gastrointestinaler Tumor (DE-588)4224415-8 gnd Therapie (DE-588)4059798-2 gnd Molekularbiologie (DE-588)4039983-7 gnd |
subject_GND | (DE-588)4170396-0 (DE-588)4224415-8 (DE-588)4059798-2 (DE-588)4039983-7 (DE-588)4143413-4 |
title | New Perspectives in Molecular and Clinical Management of Gastrointestinal Tumors |
title_auth | New Perspectives in Molecular and Clinical Management of Gastrointestinal Tumors |
title_exact_search | New Perspectives in Molecular and Clinical Management of Gastrointestinal Tumors |
title_full | New Perspectives in Molecular and Clinical Management of Gastrointestinal Tumors edited by Ernst-D. Kreuser, P. M. Schlag |
title_fullStr | New Perspectives in Molecular and Clinical Management of Gastrointestinal Tumors edited by Ernst-D. Kreuser, P. M. Schlag |
title_full_unstemmed | New Perspectives in Molecular and Clinical Management of Gastrointestinal Tumors edited by Ernst-D. Kreuser, P. M. Schlag |
title_short | New Perspectives in Molecular and Clinical Management of Gastrointestinal Tumors |
title_sort | new perspectives in molecular and clinical management of gastrointestinal tumors |
topic | Oncology Abdominal Surgery Imaging / Radiology Oncology Abdomen / Surgery Radiology, Medical Molekularpathologie (DE-588)4170396-0 gnd Gastrointestinaler Tumor (DE-588)4224415-8 gnd Therapie (DE-588)4059798-2 gnd Molekularbiologie (DE-588)4039983-7 gnd |
topic_facet | Oncology Abdominal Surgery Imaging / Radiology Oncology Abdomen / Surgery Radiology, Medical Molekularpathologie Gastrointestinaler Tumor Therapie Molekularbiologie Aufsatzsammlung |
url | https://doi.org/10.1007/978-3-642-80035-1 |
work_keys_str_mv | AT kreuserernstd newperspectivesinmolecularandclinicalmanagementofgastrointestinaltumors AT schlagpm newperspectivesinmolecularandclinicalmanagementofgastrointestinaltumors |