Protein homeostasis in drug discovery: a chemical biology perspective
"Protein homeostasis is a complex network of components and processes that maintain stability of proteins in cells. Drug discovery and development efforts have focused on developing small molecule agents that bind the target protein with the greatest affinity and most precise selectivity. Impac...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Hoboken, NJ
Wiley
2023
|
| Schlagworte: | |
| Zusammenfassung: | "Protein homeostasis is a complex network of components and processes that maintain stability of proteins in cells. Drug discovery and development efforts have focused on developing small molecule agents that bind the target protein with the greatest affinity and most precise selectivity. Impacting protein stability, cellular localization, abundance, interactions and other aspects of protein homeostasis are emerging at the forefront of translational chemical biology and medicinal chemistry efforts"-- |
| Beschreibung: | Includes index 2301 |
| Beschreibung: | xvii, 538 Seiten Illustrationen, Diagramme |
| ISBN: | 9781119774129 |
Internformat
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| 245 | 1 | 0 | |a Protein homeostasis in drug discovery |b a chemical biology perspective |c edited by Milka Kostic and Lyn H. Jones |
| 264 | 1 | |a Hoboken, NJ |b Wiley |c 2023 | |
| 300 | |a xvii, 538 Seiten |b Illustrationen, Diagramme | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 500 | |a Includes index | ||
| 500 | |a 2301 | ||
| 520 | 3 | |a "Protein homeostasis is a complex network of components and processes that maintain stability of proteins in cells. Drug discovery and development efforts have focused on developing small molecule agents that bind the target protein with the greatest affinity and most precise selectivity. Impacting protein stability, cellular localization, abundance, interactions and other aspects of protein homeostasis are emerging at the forefront of translational chemical biology and medicinal chemistry efforts"-- | |
| 653 | 0 | |a Drug development | |
| 653 | 0 | |a Homeostasis | |
| 653 | 0 | |a Proteins / Therapeutic use | |
| 653 | 0 | |a Proteostasis | |
| 653 | 0 | |a Drug Discovery | |
| 700 | 1 | |a Kostic, Milka |4 edt | |
| 700 | 1 | |a Jones, Lyn H. |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Online-Ausgabe |z 978-1-119-77417-4 |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-034267181 | ||
Datensatz im Suchindex
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| author2 | Kostic, Milka Jones, Lyn H. |
| author2_role | edt edt |
| author2_variant | m k mk l h j lh lhj |
| author_facet | Kostic, Milka Jones, Lyn H. |
| building | Verbundindex |
| bvnumber | BV049004048 |
| classification_rvk | VS 5350 |
| ctrlnum | (OCoLC)1351695039 (DE-599)BVBBV049004048 |
| discipline | Chemie / Pharmazie |
| discipline_str_mv | Chemie / Pharmazie |
| format | Book |
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| id | DE-604.BV049004048 |
| illustrated | Illustrated |
| index_date | 2024-07-03T22:10:22Z |
| indexdate | 2024-07-10T09:52:34Z |
| institution | BVB |
| isbn | 9781119774129 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-034267181 |
| oclc_num | 1351695039 |
| open_access_boolean | |
| owner | DE-19 DE-BY-UBM |
| owner_facet | DE-19 DE-BY-UBM |
| physical | xvii, 538 Seiten Illustrationen, Diagramme |
| publishDate | 2023 |
| publishDateSearch | 2023 |
| publishDateSort | 2023 |
| publisher | Wiley |
| record_format | marc |
| spelling | Protein homeostasis in drug discovery a chemical biology perspective edited by Milka Kostic and Lyn H. Jones Hoboken, NJ Wiley 2023 xvii, 538 Seiten Illustrationen, Diagramme txt rdacontent n rdamedia nc rdacarrier Includes index 2301 "Protein homeostasis is a complex network of components and processes that maintain stability of proteins in cells. Drug discovery and development efforts have focused on developing small molecule agents that bind the target protein with the greatest affinity and most precise selectivity. Impacting protein stability, cellular localization, abundance, interactions and other aspects of protein homeostasis are emerging at the forefront of translational chemical biology and medicinal chemistry efforts"-- Drug development Homeostasis Proteins / Therapeutic use Proteostasis Drug Discovery Kostic, Milka edt Jones, Lyn H. edt Erscheint auch als Online-Ausgabe 978-1-119-77417-4 |
| spellingShingle | Protein homeostasis in drug discovery a chemical biology perspective |
| title | Protein homeostasis in drug discovery a chemical biology perspective |
| title_auth | Protein homeostasis in drug discovery a chemical biology perspective |
| title_exact_search | Protein homeostasis in drug discovery a chemical biology perspective |
| title_exact_search_txtP | Protein homeostasis in drug discovery a chemical biology perspective |
| title_full | Protein homeostasis in drug discovery a chemical biology perspective edited by Milka Kostic and Lyn H. Jones |
| title_fullStr | Protein homeostasis in drug discovery a chemical biology perspective edited by Milka Kostic and Lyn H. Jones |
| title_full_unstemmed | Protein homeostasis in drug discovery a chemical biology perspective edited by Milka Kostic and Lyn H. Jones |
| title_short | Protein homeostasis in drug discovery |
| title_sort | protein homeostasis in drug discovery a chemical biology perspective |
| title_sub | a chemical biology perspective |
| work_keys_str_mv | AT kosticmilka proteinhomeostasisindrugdiscoveryachemicalbiologyperspective AT joneslynh proteinhomeostasisindrugdiscoveryachemicalbiologyperspective |