Annual Reports in Combinatorial Chemistry and Molecular Diversity:
Combinatorial chemistry and molecular diversity approaches to scientific inquiry and novel product R&D have exploded in the 1990s! For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and scr...
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| Other Authors: | , , , |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Dordrecht
Springer Netherlands
1997
|
| Series: | Annual Reports in Combinatorial Chemistry & Molecular Diversity
1 |
| Subjects: | |
| Online Access: | UBR01 Volltext |
| Summary: | Combinatorial chemistry and molecular diversity approaches to scientific inquiry and novel product R&D have exploded in the 1990s! For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds. Drug discovery - better, faster, cheaper? Indeed, more compounds have been made and screened in the 1990s than in the last hundred years of pharmaceutical research. This first volume covers: (i) combinatorial chemistry, (ii) combinatorial biology and evolution, and (iii) informatics and related topics. Within each section chapters are prepared by experts in the field, including, for example, in Section I: Coverage of mixture pools vs. parallel individual compound synthesis, solution vs. solid-phase synthesis, analytical tools, and automation. Section II highlights selection strategies and library-based evolution, phage display, peptide and nucleic acid libraries. Section III covers databases and library design, high through-put screening, coding strategies vs. deconvolutions, intellectual property issues, deals and collaborations, and successes to date |
| Physical Description: | 1 Online-Ressource (XIII, 354 p. 57 illus., 3 illus. in color) |
| ISBN: | 9780306469046 |
| DOI: | 10.1007/978-0-306-46904-6 |
Staff View
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| 520 | |a Combinatorial chemistry and molecular diversity approaches to scientific inquiry and novel product R&D have exploded in the 1990s! For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds. Drug discovery - better, faster, cheaper? Indeed, more compounds have been made and screened in the 1990s than in the last hundred years of pharmaceutical research. This first volume covers: (i) combinatorial chemistry, (ii) combinatorial biology and evolution, and (iii) informatics and related topics. Within each section chapters are prepared by experts in the field, including, for example, in Section I: Coverage of mixture pools vs. parallel individual compound synthesis, solution vs. solid-phase synthesis, analytical tools, and automation. Section II highlights selection strategies and library-based evolution, phage display, peptide and nucleic acid libraries. Section III covers databases and library design, high through-put screening, coding strategies vs. deconvolutions, intellectual property issues, deals and collaborations, and successes to date | ||
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| id | DE-604.BV046147288 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:32Z |
| institution | BVB |
| isbn | 9780306469046 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-031527473 |
| oclc_num | 1119038658 |
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| owner_facet | DE-355 DE-BY-UBR |
| physical | 1 Online-Ressource (XIII, 354 p. 57 illus., 3 illus. in color) |
| psigel | ZDB-2-SME ZDB-2-SME_1990/2004 ZDB-2-SME ZDB-2-SME_1990/2004 |
| publishDate | 1997 |
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| publisher | Springer Netherlands |
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| series2 | Annual Reports in Combinatorial Chemistry & Molecular Diversity |
| spelling | Annual Reports in Combinatorial Chemistry and Molecular Diversity edited by W. H. Moos, M. R. Pavia, B. K. Kay, A. D. Ellington Dordrecht Springer Netherlands 1997 1 Online-Ressource (XIII, 354 p. 57 illus., 3 illus. in color) txt rdacontent c rdamedia cr rdacarrier Annual Reports in Combinatorial Chemistry & Molecular Diversity 1 Combinatorial chemistry and molecular diversity approaches to scientific inquiry and novel product R&D have exploded in the 1990s! For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds. Drug discovery - better, faster, cheaper? Indeed, more compounds have been made and screened in the 1990s than in the last hundred years of pharmaceutical research. This first volume covers: (i) combinatorial chemistry, (ii) combinatorial biology and evolution, and (iii) informatics and related topics. Within each section chapters are prepared by experts in the field, including, for example, in Section I: Coverage of mixture pools vs. parallel individual compound synthesis, solution vs. solid-phase synthesis, analytical tools, and automation. Section II highlights selection strategies and library-based evolution, phage display, peptide and nucleic acid libraries. Section III covers databases and library design, high through-put screening, coding strategies vs. deconvolutions, intellectual property issues, deals and collaborations, and successes to date Pharmacy Biochemistry, general Organic Chemistry Polymer Sciences Biochemistry Chemistry, Organic Polymers Moos, W. H. edt Pavia, M. R. edt Kay, B. K. edt Ellington, A. D. edt Erscheint auch als Druck-Ausgabe 9789401707381 Erscheint auch als Druck-Ausgabe 9789401707374 Erscheint auch als Druck-Ausgabe 9789072199232 https://doi.org/10.1007/978-0-306-46904-6 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Annual Reports in Combinatorial Chemistry and Molecular Diversity Pharmacy Biochemistry, general Organic Chemistry Polymer Sciences Biochemistry Chemistry, Organic Polymers |
| title | Annual Reports in Combinatorial Chemistry and Molecular Diversity |
| title_auth | Annual Reports in Combinatorial Chemistry and Molecular Diversity |
| title_exact_search | Annual Reports in Combinatorial Chemistry and Molecular Diversity |
| title_full | Annual Reports in Combinatorial Chemistry and Molecular Diversity edited by W. H. Moos, M. R. Pavia, B. K. Kay, A. D. Ellington |
| title_fullStr | Annual Reports in Combinatorial Chemistry and Molecular Diversity edited by W. H. Moos, M. R. Pavia, B. K. Kay, A. D. Ellington |
| title_full_unstemmed | Annual Reports in Combinatorial Chemistry and Molecular Diversity edited by W. H. Moos, M. R. Pavia, B. K. Kay, A. D. Ellington |
| title_short | Annual Reports in Combinatorial Chemistry and Molecular Diversity |
| title_sort | annual reports in combinatorial chemistry and molecular diversity |
| topic | Pharmacy Biochemistry, general Organic Chemistry Polymer Sciences Biochemistry Chemistry, Organic Polymers |
| topic_facet | Pharmacy Biochemistry, general Organic Chemistry Polymer Sciences Biochemistry Chemistry, Organic Polymers |
| url | https://doi.org/10.1007/978-0-306-46904-6 |
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