Biostatistical Modeling and Analysis of Combined fMRI and EEG Measurements:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
München
Dr. Hut
2012
|
| Ausgabe: | 1. Aufl. |
| Schriftenreihe: | Statistik
|
| Schlagworte: | |
| Online-Zugang: | kostenfrei kostenfrei https://nbn-resolving.org/urn:nbn:de:bvb:19-152004 Inhaltsverzeichnis |
| Beschreibung: | XII, 270 S. Ill., graph. Darst. 210 mm x 148 mm, 468 g |
| ISBN: | 9783843907811 3843907811 |
Internformat
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| 100 | 1 | |a Kalus, Stefanie |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Biostatistical Modeling and Analysis of Combined fMRI and EEG Measurements |c Stefanie Kalus |
| 250 | |a 1. Aufl. | ||
| 264 | 1 | |a München |b Dr. Hut |c 2012 | |
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Datensatz im Suchindex
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IMAGE 1
CONTENTS
OUTLINE 1
1 INTRODUCTION 9
1.1 NEUROPHYSIOLOGICAL BASIS 9
1.1.1 NEURONAL ACTIVITY 10
1.1.2 GENERATORS OF THE EEG 12
1.1.3 GENERATORS OF THE FMRI SIGNAL 15
1.1.4 COMPARING FMRI AND EEG INFORMATION 19
1.2 THE FMRI-EEG DATA FUSION 20
1.2.1 EEG-TO-FMRI APPROACHES 23
1.2.2 FMRI-TO-EEG APPROACHES 26
1.2.3 SYMMETRICAL APPROACHES 28
1.2.4 A NEW ASYMMETRICAL EEG-TO-FMRI APPROACH 30
2 REGRESSION MODELS FOR FMRI 33
2.1 DESCRIPTION OF PREDICTOR COMPONENTS 35
2.1.1 BASELINE - MODELING OF LOW FREQUENCY CONFOUNDS 35
2.1.2 CONFOUNDING VARIABLES 37
2.1.3 MODELING EXPERIMENTAL STIMULI 38
2.1.4 LINEARIZATION OF ALL MODEL COMPONENTS 44
2.1.5 MATRIX NOTATION 46
2.2 DISTRIBUTIONAL ASSUMPTIONS ABOUT THE ERROR TERM 46
3 AN EEG-ENHANCED FMRI MODEL 49
3.1 THE FMRI REGRESSION MODEL 50
3.2 BAYESIAN ACTIVATION DETECTION 51
3.3 PRIOR SPECIFICATIONS 52
3.4 POSTERIOR INFERENCE 58
3.4.1 SAMPLING ACTIVATION PROBABILITIES 59
HTTP://D-NB.INFO/1029253552
IMAGE 2
3.4.2 BINARY REGRESSION LEVEL 61
3.4.3 ALGORITHMIC DETAILS 68
3.4.4 MONTE CARLO ESTIMATES 70
3.4.5 CLASSIFICATION OF VOXELS 72
3.5 A MODEL EXTENSION: A NON-NEGATIVE GLOBAL EEG EFFECT 77
4 A FAST CAR MODEL FOR THE EEG-ENHANCED FMRI MODEL 79
4.1 SINGLE SITE UPDATES FOR SPATIALLY-VARYING COEFFICIENTS 81
4.2 CALCULATING THE DETERMINANT OF LARGE SPARSE UPDATE MATRICES 82
4.2.1 OVERVIEW OF EXISTING METHODS 82
4.2.2 LAPLACE EIGENSPECTRUM OF GRIDS 84
4.3 AN ACCELERATED FMRI-EEG ALGORITHM 86
5 SOFTWARE IMPLEMENTATION 89
5.1 USAGE 90
5.1.1 PRELIMINARIES: CONFIGURING AN F M R I E E G ALGORITHM RUN 90
5.1.2 USAGE OF THE R-PACKAGE RFMRIEEG 92
5.1.3 COMPILATION AND USAGE OF THE EXECUTABLE CFMRIEEGMAIN 98 5.2
IMPLEMENTATIONAL ISSUES 100
5.2.1 EFFICIENT LINEAR ALGEBRA SUBPROGRAMS 100
5.2.2 EFFICIENT GMRF UPDATES VIA CHOLESKY DECOMPOSITIONS 101 5.2.3
SOFTWARE DESIGN 102
5.3 TECHNICAL NOTES 103
5.3.1 IMAGE DATA FORMAT 106
5.3.2 EXTERNAL DEPENDENCIES 107
5.3.3 INFLUENCES ON THE RUNNING TIME 107
6 SIMULATION STUDIES 111
6.1 SIMULATION STUDIES BASED ON ARTIFICIAL DATA 111
6.1.1 DESIGN FOR GENERATING AN ARTIFICIAL DATASET 112
6.1.2 NOTATION AND COMMON MODEL SETTINGS 116
6.1.3 EVALUATION OF DIFFERENT EEG PREDICTOR FORMS 117
6.1.4 COMPARISON OF DIFFERENT FMRI ACTIVATION DETECTION ALGORITHMS . . .
. 135 6.1.5 EVALUATION OF EEG-ENHANCED DETECTION SCHEMES 144
6.1.6 SUMMARY 152
6.2 SIMULATION STUDIES BASED ON REAL-WORLD DATA 154
IMAGE 3
7 APPLICATION TO AN ODDBALL STUDY 159
7.1 MATERIAL 159
7.2 METHODS 162
7.3 RESULTS 169
7.3.1 COMPARISON OF DIFFERENT FMRI ACTIVATION DETECTION ALGORITHMS . . .
. 169 7.3.2 EVALUATION OF EEG-ENHANCED FMRI DETECTION SCHEMES 178 7.4
SUMMARY 197
8 PROOF OF CONCEPT 203
9 CONCLUSION AND PERSPECTIVE 215
APPENDIX 2 2 3
A DERIVATION OF FURTHER COMPONENTS OF T H E EEG-ENHANCED FMRI MODEL 223
A.L MARGINALIZED CONDITIONAL DISTRIBUTIONS OF BINARY INDICATORS 223 A.2
CONDITIONAL POSTERIOR MEANS OF FMRI STAGE PARAMETERS 225
A.3 MARGINAL PRIOR PROBABILITY FOR ACTIVATION 227
B ROBUSTNESS OF VARIANCE PARAMETER ESTIMATION 229
B.L ROBUSTNESS OF GCAR5 RESULTS 229
B.2 ROBUSTNESS OF FCAR5 RESULTS 234
B.3 ROBUSTNESS OF IMRF5 RESULTS 237
B.4 SUMMARY 238
C IMPLEMENTATION: ARGUMENTS FOR A CALL TO THE F M R I E E G ALGORITHM
241
D SUPPLEMENTARY RESULTS: RESULTS OF SHORTENED FMRI DATA TRAJECTORIES 247
BIBLIOGRAPHY 2 5 7 |
| any_adam_object | 1 |
| author | Kalus, Stefanie |
| author_facet | Kalus, Stefanie |
| author_role | aut |
| author_sort | Kalus, Stefanie |
| author_variant | s k sk |
| building | Verbundindex |
| bvnumber | BV040675057 |
| collection | ebook |
| ctrlnum | (OCoLC)826595595 (DE-599)DNB1029253552 |
| dewey-full | 612.82 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
| dewey-raw | 612.82 |
| dewey-search | 612.82 |
| dewey-sort | 3612.82 |
| dewey-tens | 610 - Medicine and health |
| discipline | Mathematik Medizin |
| edition | 1. Aufl. |
| format | Thesis Book |
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| physical | XII, 270 S. Ill., graph. Darst. 210 mm x 148 mm, 468 g |
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| spelling | Kalus, Stefanie Verfasser aut Biostatistical Modeling and Analysis of Combined fMRI and EEG Measurements Stefanie Kalus 1. Aufl. München Dr. Hut 2012 XII, 270 S. Ill., graph. Darst. 210 mm x 148 mm, 468 g txt rdacontent n rdamedia nc rdacarrier Statistik Zugl.: München, Univ., Diss., 2012 Funktionelle Kernspintomografie (DE-588)7618675-1 gnd rswk-swf Bayes-Verfahren (DE-588)4204326-8 gnd rswk-swf Mapping Medizin (DE-588)4481430-6 gnd rswk-swf Biostatistik (DE-588)4729990-3 gnd rswk-swf Elektroencephalographie (DE-588)4014254-1 gnd rswk-swf Hirnfunktion (DE-588)4159930-5 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Hirnfunktion (DE-588)4159930-5 s Mapping Medizin (DE-588)4481430-6 s Funktionelle Kernspintomografie (DE-588)7618675-1 s Elektroencephalographie (DE-588)4014254-1 s Bayes-Verfahren (DE-588)4204326-8 s Biostatistik (DE-588)4729990-3 s DE-604 Erscheint auch als Online-Ausgabe urn:nbn:de:bvb:19-152004 X:MVB text/html http://deposit.dnb.de/cgi-bin/dokserv?id=4220783&prov=M&dok_var=1&dok_ext=htm Verlag kostenfrei Inhaltstext http://edoc.ub.uni-muenchen.de/15200/ Verlag kostenfrei Volltext https://nbn-resolving.org/urn:nbn:de:bvb:19-152004 Resolving-System DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025501550&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Kalus, Stefanie Biostatistical Modeling and Analysis of Combined fMRI and EEG Measurements Funktionelle Kernspintomografie (DE-588)7618675-1 gnd Bayes-Verfahren (DE-588)4204326-8 gnd Mapping Medizin (DE-588)4481430-6 gnd Biostatistik (DE-588)4729990-3 gnd Elektroencephalographie (DE-588)4014254-1 gnd Hirnfunktion (DE-588)4159930-5 gnd |
| subject_GND | (DE-588)7618675-1 (DE-588)4204326-8 (DE-588)4481430-6 (DE-588)4729990-3 (DE-588)4014254-1 (DE-588)4159930-5 (DE-588)4113937-9 |
| title | Biostatistical Modeling and Analysis of Combined fMRI and EEG Measurements |
| title_auth | Biostatistical Modeling and Analysis of Combined fMRI and EEG Measurements |
| title_exact_search | Biostatistical Modeling and Analysis of Combined fMRI and EEG Measurements |
| title_full | Biostatistical Modeling and Analysis of Combined fMRI and EEG Measurements Stefanie Kalus |
| title_fullStr | Biostatistical Modeling and Analysis of Combined fMRI and EEG Measurements Stefanie Kalus |
| title_full_unstemmed | Biostatistical Modeling and Analysis of Combined fMRI and EEG Measurements Stefanie Kalus |
| title_short | Biostatistical Modeling and Analysis of Combined fMRI and EEG Measurements |
| title_sort | biostatistical modeling and analysis of combined fmri and eeg measurements |
| topic | Funktionelle Kernspintomografie (DE-588)7618675-1 gnd Bayes-Verfahren (DE-588)4204326-8 gnd Mapping Medizin (DE-588)4481430-6 gnd Biostatistik (DE-588)4729990-3 gnd Elektroencephalographie (DE-588)4014254-1 gnd Hirnfunktion (DE-588)4159930-5 gnd |
| topic_facet | Funktionelle Kernspintomografie Bayes-Verfahren Mapping Medizin Biostatistik Elektroencephalographie Hirnfunktion Hochschulschrift |
| url | http://deposit.dnb.de/cgi-bin/dokserv?id=4220783&prov=M&dok_var=1&dok_ext=htm http://edoc.ub.uni-muenchen.de/15200/ https://nbn-resolving.org/urn:nbn:de:bvb:19-152004 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025501550&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT kalusstefanie biostatisticalmodelingandanalysisofcombinedfmriandeegmeasurements |