The neural crest:
"This fully revised edition of The Neural Crest contains the most current information about the neural crest, a structure unique to the vertebrate embryo which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developm...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Cambridge [u.a.]
Cambridge Univ. Press
1999
|
| Ausgabe: | 2. ed. |
| Schriftenreihe: | Developmental and cell biology series
36 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Zusammenfassung: | "This fully revised edition of The Neural Crest contains the most current information about the neural crest, a structure unique to the vertebrate embryo which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum."--BOOK JACKET. "This new edition also covers recent advances in our understanding of markers of neural crest cell subpopulations. Cell lineage analysis is a field in neural crest development that has also significantly contributed to an understanding of the phenotypic segregation of neural crest cell subpopulations, and a full chapter is now devoted to this issue."--BOOK JACKET. "This book is for students and researchers in developmental biology, cell biology, and neuroscience."--BOOK JACKET. "Developmental and Cell Biology Series 36."--BOOK JACKET. |
| Beschreibung: | XXIII, 445 S. Ill., graph. Darst. |
| ISBN: | 0521620104 |
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| 490 | 1 | |a Developmental and cell biology series |v 36 | |
| 520 | 1 | |a "This fully revised edition of The Neural Crest contains the most current information about the neural crest, a structure unique to the vertebrate embryo which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum."--BOOK JACKET. "This new edition also covers recent advances in our understanding of markers of neural crest cell subpopulations. Cell lineage analysis is a field in neural crest development that has also significantly contributed to an understanding of the phenotypic segregation of neural crest cell subpopulations, and a full chapter is now devoted to this issue."--BOOK JACKET. "This book is for students and researchers in developmental biology, cell biology, and neuroscience."--BOOK JACKET. "Developmental and Cell Biology Series 36."--BOOK JACKET. | |
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Datensatz im Suchindex
| _version_ | 1804128937728540672 |
|---|---|
| adam_text | Contents
Foreword xvii
Preface xix
General Introduction xxi
1 Methods for Identifying Neural Crest Cells and Their Derivatives 1
1.1 Introduction 1
1.2 Extirpation or in situ destruction of the neural crest 2
1.3 Differential identification of neural crest cells throughout
ontogeny 2
1.3.1 Intrinsic markers of neural crest cells 3
1.3.2 Extrinsic markers applied to neural crest precursor cells 9
1.3.3 The quail chick marker system 10
2 The Migration of Neural Crest Cells 23
2.1 Introduction 23
2.2 Segregation of the neural crest from the neuroepithelium 24
2.2.1 Induction of the neural crest 24
2.2.2 Epithelial mesenchymal transition and the onset of
neural crest migration 27
2.3 The cellular basis of neural crest migration 34
2.3.1 Pathways of migration related to fate 34
2.3.2 Similarities and differences in the pathways of migration
between different species 38
2.4 The molecular basis of neural crest migration 44
2.4.1 Delayed migration along the subectodermal pathway:
transient inhibition or the need for cell specification 45
X CONTENTS
2.4.2 Molecular signals Controlling segmental migration in
the trunk 48
2.5 Conclusions 58
3 The Neural Crest: A Source of Mesenchymal Cells 60
3.1 Historical overview 60
3.1.1 The notion of mesectoderm 60
3.1.2 Pioneering work on the amphibian embryo and
lower vertebrates 61
3.1.3 The modern era 65
3.2 The fate of the mesectodermal cells in the head 65
3.2.1 Labeling the cephalic neural crest cells in the avian
embryo 66
3.2.2 Derivatives of the cephalic neural crest 68
3.2.3 Analysis of the cephalic crest cell migration and
fate in mammalian embryos 77
3.2.4 The fate of the anterior cephalic neural fold and
neural plate corresponding to the prosencephalon
studied in the avian embryo 82
3.3 Relationships between the cephalic paraxial mesoderm and
the neural crest derived mesectoderm 85
3.3.1 The contribution of the paraxial cephalic mesoderm
to the skull 85
3.3.2 Analogies and differences between cephalic and
truncal paraxial mesoderm 87
3.3.3 The notion of prechordal and chordal skull 90
3.4 Segmental nature of the brain primordium: molecular
implications for neural crest development 91
3.4.1 The cellular basis of hindbrain segmentation 92
3.4.2 Molecular basis of hindbrain segmentation 93
3.4.3 Forebrain and midbrain segmentation 106
3.5 Relationships between brain segmentation and the
development of the cranial, facial, and visceral skeleton 107
3.5.1 Evidence for the contribution of each rhombomere
to the branchial arches as revealed by Dil labeling 107
3.5.2 Determination of the long term fate of neural crest
cells of mesencephalic and rhombomeric origin 110
3.5.3 Regeneration capabilities of the cephalic neural crest 115
3.5.4 Patterning capacities of the neural crest 119
3.6 Genetic analysis of the development of the mesectodermal
derivatives of the neural crest: roles of Hox genes and
retinoic acid (RA) 124
3.6.1 Disruption of certain Hox genes of the first paralogous
groups interferes with the development of neural
crest derived branchial arches structures 124
CONTENTS xi
3.6.2 Role of RA in the development of hindbrain and of
its neural crest derivatives 130
3.7 A number of transcription factors are involved in the
ontogeny of the mesectodermal derivatives of the neural
crest 140
3.7.1 Otx genes 141
3.7.2 Mhox gene 142
3.7.3 Goosecoid gene 142
3.7.4 Dlx genes 143
3.7.5 Pax genes 144
3.7.6 The Cart 1 homeobox gene 145
3.7.7 Msx genes 146
3.7.8 Twist gene 147
3.7.9 AP2 gene 149
3.8 Roles of various growth factors in the development of the
mesectodermal derivatives of the neural crest 149
3.8.1 The endothelin 1 receptor A pathway 150
3.8.2 Other growth factors involved in mesectoderm
development 151
4 From the Neural Crest to the Ganglia of the Peripheral Nervous System:
The Sensory Ganglia 153
4.1 General considerations 153
4.2 How is the segmental distribution of spinal ganglia
established? 155
4.3 Embryonic origin and cellular heterogeneity of cranial and
spinal ganglia 159
4.3.1 Embryonic origin of cranial sensory ganglia 159
4.3.2 The mesencephalic nucleus of the trigeminal nerve 162
4.3.3 The cells of Rohon Beard 164
4.3.4 Different types of neurons in spinal sensory ganglia 164
4.3.5 Differential expression of markers to subsets of
sensory neurons 165
4.3.6 Differential response of sensory neurons to growth
factors 166
4.4 Control of cell number in developing ganglia 168
4.4.1 Control of the development of sensory neural crest
progenitors by the microenvironment 168
4.4.2 Trophic control of neural crest development 172
4.4.3 Early stages of sensory ganglion development 177
4.4.4 Neurotrophic activities during the period of normal
neuronal death 182
4.4.5 Target derived survival factors 184
4.4.6 Developmental sequence and overlapping activities
of neurotrophins during development of sensory
neurons 190
XÜ CONTENTS
4.4.7 Modulation of responsiveness to neurotrophins by
the neurofibromin gene product 192
4.4.8 Evidence for autocrine and paracrine effects of
neurotrophins 194
5 The Autonomie Nervous System and the Endocrine Cells of Neural
Crest Origin 197
5.1 General considerations 197
5.2 Origin and migratory pathways followed by distinet
autonomic progenitors 198
5.2.1 The sympathetic ganglia 198
5.2.2 The adrenal medulla 203
5.2.3 The parasympathetic ganglia 203
5.2.4 The enteric nervous System 204
5.3 Transmitter phenotypes and markers of developing
autonomic sublineages 208
5.3.1 Transmitter phenotypes of embryonic sympathetic
neurons 208
5.3.2 Modulation of the catecholaminergic phenotype
during development 209
5.3.3 Neurotransmitter plasticity in the autonomic
nervous System 210
5.4 Development of autonomic cells from the neural crest 213
5.4.1 Factors that affect initial development of
adrenergic cells 213
5.4.2 Control of the proliferation of sympathetic
neuroblasts and chromaffin cells 216
5.4.3 Sequential and synergistic activities of growth factors
on the differentiation of sympathetic neuroblasts 219
5.4.4 Requirements for chromaffin cell differentiation 221
5.5 The relationship between sympathetic, adrenomedullary, and
enteric progenitor cells 223
5.5.1 Expression in common of neuronal and chromaffin
speeifie markers 224
5.5.2 The problem of a common lineage for adrenomedullary
cells, sympathetic progenitors, and the enteric neurons 224
5.6 Regulation of the survival of sympathetic and parasympathetic
neurons 228
5.6.1 Differential roles of neurotrophins 228
5.6.2 Ciliary neurons and CNTF 229
5.7 The enteric nervous System 230
5.7.1 Factors affecting the differentiation of enteric neurons:
neurotrophin 3 230
5.7.2 The molecular basis of the megacolon phenotype:
the lethal spotted and piebald lethal mouse mutants as
modeis for aneural hindgut 231
CONTENTS xiü
5.7.3 The endothelin 3 peptide and the endothelin B receptor
are encoded respectively by the genes mutated in the
lethal spotted and piebald lethal mice 234
5.7.4 The ret receptor and glial cell line derived neurotrophic
factor (GDNF) 235
5.7.5 Conclusions 239
5.8 Developmental relationships between the neural crest and
endocrine cells 240
5.8.1 Historical overview 240
5.8.2 Critical appraisal of the concept of a diffuse
neuroendocrine System 243
5.8.3 Neurectodermal origin of the calcitonin producing
cells 244
5.8.4 Origin of the carotid body 247
5.8.5 Embryological analysis of the origin of the pancreatic
islet cells and of the APUD cells of the gut epithelium 248
5.8.6 Concluding remarks 251
6 The Neural Crest: Source of the Pigment Cells 252
6.1 The various types of pigment cells 254
6.1.1 Melanophores, melanocytes, and melanins 254
6.1.2 Iridophores 259
6.1.3 Xanthophores and erythrophores 259
6.2 Development of pigment cells 259
6.2.1 A common precursor for all types of pigment cells 259
6.2.2 Neural crest origin of pigment cells 260
6.3 Migration, homing, and differentiation of presumptive
pigment cells 262
6.3.1 Migration of the pigment cell precursors in the
avian embryo 262
6.3.2 Migration of melanocytic precursors in non avian
vertebrate species 266
6.3.3 Clonal model of melanoblast development deduced
from the pigment pattern of tetraparental mice 271
6.4 The differentiation of pigment cell precursors 272
6.4.1 Molecular markers of melanocytic precursor cells 272
6.4.2 In vitro studies of melanocyte differentiation from
neural crest progenitors 273
6.5 Spotting mutants in mouse reveal the nature of growth and
survival factors for melanocytic precursors 276
6.5.1 Dominant spotting (W) and Steel (Sl) mutants 277
6.5.2 Piebald lethal (/) and lethal spotted (Is) mutants 285
6.5.3 Respective roles of c kit/SF and EDNRB B2/EDN3
signaling Systems on pigmentation 289
6.5.4 Dependence of melanocyte development on the Mitf
basic helix loop helix zipper transcription factor 293
xiv CONTENTS
6.6 Some aspects of the hormonal control of pigmentation 294
6.6.1 Control of pigmentation by the melanocyte
stimulating hormone 295
6.6.2 Coat color mutants in mice show that skin and
hair pigmentation is regulated by endocrine and
paracrine mechanisms 297
6.6.3 Paracrine control of pigmentation 298
7 Cell Lineage Segregation During Neural Crest Ontogeny 304
7.1 Introduction 304
7.2 Heterogeneity among neural crest cells is revealed by
differential expression of a variety of molecules 306
7.2.1 Monoclonal antibodies have led to subpopulations
being distinguished in the early migratory neural
crest 306
7.2.2 The presence of various transcription factors allows
recognition of different subpopulations of neural
crest cells 308
7.3 Studying developmental potencies of neural crest cell
populations 309
7.3.1 The behavior of cell populations in heterotopic
grafts 309
7.3.2 A time dependent topographical segregation of
peripheral progenitor cells: possible significance
for understanding neural crest plasticity 311
7.3.3 Single cell analysis of the neural crest 313
7.3.4 In vitro cloning of neural crest cells 313
7.3.5 Heterogeneity of neural crest cells is revealed by
in vitro clonal analysis 314
7.3.6 Single cell lineage analysis in vivo 319
7.4 The segregation of specific neural crest derived lineages 323
7.4.1 Sensory and autonomic neuronal lineages 323
7.4.2 Existence of distinct sensory and autonomic neuronal
progenitors in the migrating neural crest 326
7.4.3 Existence of autonomic progenitors in all peripheral
ganglia 327
7.4.4 Differential environmental requirements of sensory
and autonomic neurons 327
7.5 Glial lineages in neural crest ontogeny 328
7.5.1 Origin and diversity of glial cells 328
7.5.2 Early markers of glial development 329
7.5.3 The lineage relations of glial cells 330
7.6 Factors affecting development of neuronal and glial
lineages from the neural crest 332
7.6.1 Determination versus differentiation 332
CONTENTS XV
7.6.2 Phenotypic diversification in a homogeneous
environment 334
8 Concluding Remarks and Perspectives 336
References 339
Author Index 433
Subject Index 442
|
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| id | DE-604.BV014074878 |
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| indexdate | 2024-07-09T18:57:11Z |
| institution | BVB |
| isbn | 0521620104 |
| language | English |
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| spelling | Le Douarin, Nicole 1930- Verfasser (DE-588)140867635 aut The neural crest Nicole Le Douarin ; Chaya Kalcheim 2. ed. Cambridge [u.a.] Cambridge Univ. Press 1999 XXIII, 445 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Developmental and cell biology series 36 "This fully revised edition of The Neural Crest contains the most current information about the neural crest, a structure unique to the vertebrate embryo which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum."--BOOK JACKET. "This new edition also covers recent advances in our understanding of markers of neural crest cell subpopulations. Cell lineage analysis is a field in neural crest development that has also significantly contributed to an understanding of the phenotypic segregation of neural crest cell subpopulations, and a full chapter is now devoted to this issue."--BOOK JACKET. "This book is for students and researchers in developmental biology, cell biology, and neuroscience."--BOOK JACKET. "Developmental and Cell Biology Series 36."--BOOK JACKET. Neural crest Neuralleiste (DE-588)4503267-1 gnd rswk-swf Neuralleiste (DE-588)4503267-1 s 1\p DE-604 Kalcheim, Chaya Verfasser aut Developmental and cell biology series 36 (DE-604)BV002791391 36 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009639856&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Le Douarin, Nicole 1930- Kalcheim, Chaya The neural crest Developmental and cell biology series Neural crest Neuralleiste (DE-588)4503267-1 gnd |
| subject_GND | (DE-588)4503267-1 |
| title | The neural crest |
| title_auth | The neural crest |
| title_exact_search | The neural crest |
| title_full | The neural crest Nicole Le Douarin ; Chaya Kalcheim |
| title_fullStr | The neural crest Nicole Le Douarin ; Chaya Kalcheim |
| title_full_unstemmed | The neural crest Nicole Le Douarin ; Chaya Kalcheim |
| title_short | The neural crest |
| title_sort | the neural crest |
| topic | Neural crest Neuralleiste (DE-588)4503267-1 gnd |
| topic_facet | Neural crest Neuralleiste |
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