An introduction to the interpretation of quantal responses in biology:
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
London
Arnold
1979
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | VI, 82 S. graph. Darst. |
| ISBN: | 0713127422 |
Internformat
MARC
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| 100 | 1 | |a Hewlett, P. S. |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a An introduction to the interpretation of quantal responses in biology |c P. S. Hewlett ; Robert L. Plackett* |
| 246 | 1 | 3 | |a The interpretation of quantal responses in biology |
| 264 | 1 | |a London |b Arnold |c 1979 | |
| 300 | |a VI, 82 S. |b graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 4 | |a Organisms - Quantal responses Mathematical models | |
| 650 | 4 | |a Mathematisches Modell | |
| 650 | 4 | |a Biology | |
| 650 | 4 | |a Biology |x Mathematical models | |
| 650 | 4 | |a Dose-Response Relationship, Drug | |
| 650 | 4 | |a Drugs |x Dose-response relationship | |
| 650 | 4 | |a Logits | |
| 650 | 4 | |a Models, Theoretical | |
| 650 | 4 | |a Pesticides |x Dose-response relationship | |
| 650 | 4 | |a Probits | |
| 650 | 4 | |a Quantum Theory | |
| 700 | 1 | |a Plackett, Robert L. |e Verfasser |4 aut | |
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Datensatz im Suchindex
| _version_ | 1804123662803009536 |
|---|---|
| adam_text | IMAGE 1
CONTENTS
PREFACE III
1 INTRODUCTION 1
1.1 THE CONCEPT OF QUANTAL RESPONSE 1
1.2 CORRECTION FOR CONTROL RESPONSE 2
1.3 UNIFORMITY TRIALS FOR TESTING TECHNIQUES 2
1.4 COMPARISON OF TWO PERCENTAGE RESPONSES 3
2 THE TYPICAL DOSE-RESPONSE CURVE 6
2.1 THE SHAPE OF THE TYPICAL CURVE 6
2.2 THE EFFECT OF TAKING LOGARITHMS 7
2.3 INTERPRETATION OF THE LOG-DOSE RESPONSE CURVE 7
2.4 MATHEMATICAL STATEMENT 8
2.5 EXPERIMENTAL SUPPORT FOR THE CONCEPT OF TOLERANCE 9
2.6 ATYPICAL RESPONSE CURVES 11
3 THE PROBIT AND SIMILAR TRANSFORMATIONS 12
3.1 REPRESENTATION OF LINEAR RELATIONS BY ADJACENT SCALES 12
3.2 AN INFORMAL EXPLANATION OF THE PROBIT TRANSFORMATION 13 3.3 AN
EXPERIMENTAL EXAMPLE 14
3.4 MATHEMATICAL STATEMENT OF THE PROBIT TRANSFORMATION 15 3.5 RELATIVE
POTENCY AND BIOASSAY 16
3.6 OTHER TRANSFORMATIONS 17
3.7 THE PROBIT PLANE 17
3.8 INCOMPLETE DOSE CONTROL 18
4 THE LOGIT TRANSFORMATION 19
4.1 AN INFORMAL EXPLANATION OF THE LOGIT TRANSFORMATION 19
4.2 A COMPARISON OF PROBITS AND LOGITS 20
4.3 MATHEMATICAL STATEMENT OF THE LOGIT TRANSFORMATION 20
5 CALCULATIONS IN PROBIT ANALYSIS 22
5.1 MAXIMUM LIKELIHOOD FITTING OF A PROBIT LINE 22
5.2 FIRST-CYCLE COMPUTATIONS 23
5.3 SHORTENED APPROXIMATE ANALYSIS 25
5.4 GOODNESS OF FIT 29
6 CALCULATIONS IN LOGIT ANALYSIS 31
6.1 INTRODUCTION 31
IMAGE 2
6.2 M I N I M UM LOGIT CHI-SQUARE 31
6.3 M A X I M UM LIKELIHOOD 34
6.4 G O O D N E SS OF FIT 35
6.5 USE OF PORTABLE PROGRAMMABLE CALCULATORS 36
7 QUANTAL RESPONSES TO MIXTURES OF DRUGS 38
7.1 GENERALITIES 38
7.2 TYPES OF MODEL 39
7.3 MODELS FROM ISOBOLOGRAMS 40
7.4 A MODEL FOR SYNERGISM 41
7.5 MODELS FOR POTENTIATION 42
7.6 COALITIVE ACTION 43
7.7 MODELS FROM GENERAL BIOLOGICAL CONCEPTS 43
7.8 SIMPLE SIMILAR ACTION 44
7.9 SIMPLE SIMILAR ACTION WITH POSITIVE CORRELATION OF TOLERANCES 45
7.10 INDEPENDENT ACTION 47
7.11 GENERAL MODELS FOR NON-INTERACTIVE ACTION 48
7.12 FITTING TO DATA OF MODELS FOR NON-INTERACTIVE ACTION 49
7.13 MODELS FROM DRUG-RECEPTOR THEORY 50
7.14 MEASUREMENT OF THE POTENCIES OF DRUG MIXTURES 53
7.15 DESIGN OF EXPERIMENTS ON JOINT DRUG ACTION 55
8 DOSE-RESPONSE CURVES FROM HETEROGENEOUS POPULATIONS AND DETECTION OF
RESISTANCE IN INSECTS 5 7
8.1 DOSE-RESPONSE CURVES 57
8.2 MONITORING OF INSECT POPULATIONS FOR RESISTANCE 60
9 TIME AND RESPONSE 62
9.1 INTRODUCTION 62
9.2 ANALYSIS OF A SET OF TIME-MORTALITY DATA 63
9.3 TIME OF OBSERVATION FOR DOSE-MORTALITY DATA 66
10 THE GENERAL NATURE OF QUANTAL RESPONSE 68
10.1 INTRODUCTION 68
10.2 A UNIFYING HYPOTHESIS 68
10.3 FORMULATION OF QUANTAL RESPONSES 69
10.4 FORMULATION OF GRADED RESPONSES 69
10.5 CONNECTION OF THE TWO ANALYSES 70
10.6 TESTING THE THEORY 71
APPENDIX: PORTABLE PROGRAMMABLE CALCULATORS IN LOGIT AND PROBIT
ANALYSIS 72
REFERENCES 72
INDEX 80
|
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| dewey-tens | 570 - Biology |
| discipline | Biologie |
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| id | DE-604.BV009220181 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T17:33:20Z |
| institution | BVB |
| isbn | 0713127422 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-006129932 |
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| physical | VI, 82 S. graph. Darst. |
| publishDate | 1979 |
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| publisher | Arnold |
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| spelling | Hewlett, P. S. Verfasser aut An introduction to the interpretation of quantal responses in biology P. S. Hewlett ; Robert L. Plackett* The interpretation of quantal responses in biology London Arnold 1979 VI, 82 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Organisms - Quantal responses Mathematical models Mathematisches Modell Biology Biology Mathematical models Dose-Response Relationship, Drug Drugs Dose-response relationship Logits Models, Theoretical Pesticides Dose-response relationship Probits Quantum Theory Plackett, Robert L. Verfasser aut SWB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006129932&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Hewlett, P. S. Plackett, Robert L. An introduction to the interpretation of quantal responses in biology Organisms - Quantal responses Mathematical models Mathematisches Modell Biology Biology Mathematical models Dose-Response Relationship, Drug Drugs Dose-response relationship Logits Models, Theoretical Pesticides Dose-response relationship Probits Quantum Theory |
| title | An introduction to the interpretation of quantal responses in biology |
| title_alt | The interpretation of quantal responses in biology |
| title_auth | An introduction to the interpretation of quantal responses in biology |
| title_exact_search | An introduction to the interpretation of quantal responses in biology |
| title_full | An introduction to the interpretation of quantal responses in biology P. S. Hewlett ; Robert L. Plackett* |
| title_fullStr | An introduction to the interpretation of quantal responses in biology P. S. Hewlett ; Robert L. Plackett* |
| title_full_unstemmed | An introduction to the interpretation of quantal responses in biology P. S. Hewlett ; Robert L. Plackett* |
| title_short | An introduction to the interpretation of quantal responses in biology |
| title_sort | an introduction to the interpretation of quantal responses in biology |
| topic | Organisms - Quantal responses Mathematical models Mathematisches Modell Biology Biology Mathematical models Dose-Response Relationship, Drug Drugs Dose-response relationship Logits Models, Theoretical Pesticides Dose-response relationship Probits Quantum Theory |
| topic_facet | Organisms - Quantal responses Mathematical models Mathematisches Modell Biology Biology Mathematical models Dose-Response Relationship, Drug Drugs Dose-response relationship Logits Models, Theoretical Pesticides Dose-response relationship Probits Quantum Theory |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=006129932&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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