Vaccinia virus-encoded bacterial beta-glucuronidase as a diagnostic biomarker for oncolytic virotherapy:
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online-Zugang: | Volltext Inhaltsverzeichnis |
| Beschreibung: | Online erschienen: 2014. - Zsfassung in dt. und engl. Sprache |
| Beschreibung: | 204 S. Ill., graph. Darst. |
Internformat
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| 246 | 1 | 3 | |a Vaccinia Virus-codierte bakterielle Beta-Glucuronidase als diagnostischer Biomarker in der onkolytischen Virotherapie |
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Datensatz im Suchindex
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| adam_text | JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG
FAKULTAT FUR BIOLOGIE
VACCINIA VIRUS-ENCODED BACTERIAL BETA-GLUCURONIDASE AS A
DIAGNOSTIC BIOMARKER FOR ONCOLYTIC VIROTHERAPY
DISSERTATION
ZUR ERLANGUNG DES NATURWISSENSCHAFTLICHEN DOKTORGRADES
DER JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG
VORGELEGT VON MICHAEL HE&
AUS KOBLENZ
WURZBURG, 2013
HTTP://D-NB.INFO/1058765604
TABLE OF CONTENTS
1. ZUSAMMENFASSUNG 1
2. SUMMARY 3
3. INTRODUCTION 5
3.1 THE COMPLEXITY OF CANCER 5
3.2 STANDARD DIAGNOSTIC AND
THERAPEUTIC PROCEDURES IN CANCER TREATMENT 8
3.3 ONCOLYTIC VIRUSES 9
3.4 ONCOLYTIC VIRUSES AS THERANOSTIC AGENTS 10
3.5 VISUALIZATION OF ONCOLYTIC VIROTHERAPY 10
3.6 BIOMARKERS IN CANCER
DIAGNOSIS 29
3.7 REFERENCES 30
4. GOALS OF THIS THESIS 33
5. RESULTS 35
5.1 BETA-GLUCURONIDASE AS A PHARMACOKINETIC BIOMARKER FOR ONCOLYTIC
VIROTHERAPY 35
5.2 BETA-GLUCURONIDASE AS A
PRECLINICAL IMAGING
MARKER 91
5.3 VACCINIA VIRUS-ENCODED ENZYMES AS PRODRUG-ACTIVATING TOOLS 93
5.4 ADDITIONAL ASPECTS OF ONCOLYTIC VIROTHERAPY 115
6. DISCUSSION 189
6.1 REFERENCES 195
7. APPENDIX 197
7.1 ACKNOWLEDGEMENT 199
7.2 CURRICULUM VITAE 201
7.3 PUBLICATIONS 203
|
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| spelling | Heß, Michael 1983- Verfasser (DE-588)1059082381 aut Vaccinia virus-encoded bacterial beta-glucuronidase as a diagnostic biomarker for oncolytic virotherapy von Michael Heß Vaccinia Virus-codierte bakterielle Beta-Glucuronidase als diagnostischer Biomarker in der onkolytischen Virotherapie 2013 204 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Online erschienen: 2014. - Zsfassung in dt. und engl. Sprache Würzburg, Univ., Diss., 2013 Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Glucuronidase beta- (DE-588)4157690-1 gnd rswk-swf Vaccinia-Virus (DE-588)4187306-3 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Glucuronidase beta- (DE-588)4157690-1 s Krebs Medizin (DE-588)4073781-0 s Vaccinia-Virus (DE-588)4187306-3 s DE-604 Erscheint auch als Online-Ausgabe urn:nbn:de:bvb:20-opus-86789 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-86789 Resolving-System kostenfrei Volltext DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027656767&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Heß, Michael 1983- Vaccinia virus-encoded bacterial beta-glucuronidase as a diagnostic biomarker for oncolytic virotherapy Krebs Medizin (DE-588)4073781-0 gnd Glucuronidase beta- (DE-588)4157690-1 gnd Vaccinia-Virus (DE-588)4187306-3 gnd |
| subject_GND | (DE-588)4073781-0 (DE-588)4157690-1 (DE-588)4187306-3 (DE-588)4113937-9 |
| title | Vaccinia virus-encoded bacterial beta-glucuronidase as a diagnostic biomarker for oncolytic virotherapy |
| title_alt | Vaccinia Virus-codierte bakterielle Beta-Glucuronidase als diagnostischer Biomarker in der onkolytischen Virotherapie |
| title_auth | Vaccinia virus-encoded bacterial beta-glucuronidase as a diagnostic biomarker for oncolytic virotherapy |
| title_exact_search | Vaccinia virus-encoded bacterial beta-glucuronidase as a diagnostic biomarker for oncolytic virotherapy |
| title_full | Vaccinia virus-encoded bacterial beta-glucuronidase as a diagnostic biomarker for oncolytic virotherapy von Michael Heß |
| title_fullStr | Vaccinia virus-encoded bacterial beta-glucuronidase as a diagnostic biomarker for oncolytic virotherapy von Michael Heß |
| title_full_unstemmed | Vaccinia virus-encoded bacterial beta-glucuronidase as a diagnostic biomarker for oncolytic virotherapy von Michael Heß |
| title_short | Vaccinia virus-encoded bacterial beta-glucuronidase as a diagnostic biomarker for oncolytic virotherapy |
| title_sort | vaccinia virus encoded bacterial beta glucuronidase as a diagnostic biomarker for oncolytic virotherapy |
| topic | Krebs Medizin (DE-588)4073781-0 gnd Glucuronidase beta- (DE-588)4157690-1 gnd Vaccinia-Virus (DE-588)4187306-3 gnd |
| topic_facet | Krebs Medizin Glucuronidase beta- Vaccinia-Virus Hochschulschrift |
| url | https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-86789 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027656767&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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