Rat genomics:
This book provides both historical perspective and practical information to support researchers either currently involved in genomic research on rats or planning to begin such a project. In numerous chapters, a detailed protocol is provided for researchers looking to move into a new area of investig...
Gespeichert in:
| Weitere Verfasser: | , , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
2019
|
| Ausgabe: | 1st ed. 2019 |
| Schriftenreihe: | Methods in Molecular Biology
2018 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 URL des Erstveröffentlichers |
| Zusammenfassung: | This book provides both historical perspective and practical information to support researchers either currently involved in genomic research on rats or planning to begin such a project. In numerous chapters, a detailed protocol is provided for researchers looking to move into a new area of investigation or to leverage a new technology. In other cases, a detailed review of existing models or a description of available resources can help the researcher find, understand, and utilize the information, the data, and the tools that they need to support their research efforts. Written as part of the highly successful Methods in Molecular Biology series, this collection includes the kind of hands-on detail necessary for success in the lab. Authoritative and up-to-date, Rat Genomics explores the rat as a biomedical model uniquely poised to provide the ideal combination of established experimental models, extensive physiological data, and genomic manipulability to facilitate exploration of the underlying biology |
| Beschreibung: | The Rat: A Model Used in Biomedical Research -- Rat Genome Assemblies, Annotation, and Variant Repository -- Rat Genome Databases, Repositories, and Tools -- Next Generation Transgenic Rat Model Production -- Embryonic Stem Cells and Gene Manipulation in Rat -- Protocols for Cryopreservation and Rederivation of Rat Gametes -- Fluorescent Imaging and Microscopy for Dynamic Processes in Rats -- Library Preparation for Multiplexed Reduced Representation Bisulfite Sequencing with a Universal Adapter -- Characterization of the Rat Gut Microbiota via 16S rRNA Amplicon Library Sequencing -- Networking in Biology: The Hybrid Rat Diversity Panel -- Using Heterogeneous Stocks for Fine-Mapping Genetically Complex Traits -- Mapping Mammary Tumor Traits in the Rat -- Rat Models of Metabolic Syndrome -- Genomic Research in Rat Models of Kidney Disease -- Rat Models of Exercise for the Study of Complex Disease -- Behavioral Genetic Studies in Rats |
| Beschreibung: | 1 Online-Ressource (XV, 331 Seiten) Illustrationen |
| ISBN: | 9781493995813 |
| DOI: | 10.1007/978-1-4939-9581-3 |
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| 520 | |a This book provides both historical perspective and practical information to support researchers either currently involved in genomic research on rats or planning to begin such a project. In numerous chapters, a detailed protocol is provided for researchers looking to move into a new area of investigation or to leverage a new technology. In other cases, a detailed review of existing models or a description of available resources can help the researcher find, understand, and utilize the information, the data, and the tools that they need to support their research efforts. Written as part of the highly successful Methods in Molecular Biology series, this collection includes the kind of hands-on detail necessary for success in the lab. Authoritative and up-to-date, Rat Genomics explores the rat as a biomedical model uniquely poised to provide the ideal combination of established experimental models, extensive physiological data, and genomic manipulability to facilitate exploration of the underlying biology | ||
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| author2 | Hayman, G. Thomas ca. 20./21. Jh Smith, Jennifer R. ca. 20./21. Jh Dwinell, Melinda R. ca. 20./21. Jh Shimoyama, Mary ca. 20./21. Jh |
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| dewey-full | 591.35 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 591 - Specific topics in natural history of animals |
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| discipline | Biologie |
| discipline_str_mv | Biologie |
| doi_str_mv | 10.1007/978-1-4939-9581-3 |
| edition | 1st ed. 2019 |
| format | Electronic eBook |
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| id | DE-604.BV047645148 |
| illustrated | Not Illustrated |
| index_date | 2024-07-03T18:48:35Z |
| indexdate | 2024-07-10T09:18:09Z |
| institution | BVB |
| isbn | 9781493995813 |
| language | English |
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| spelling | Rat genomics edited by G. Thomas Hayman, Jennifer R. Smith, Melinda R. Dwinell, Mary Shimoyama 1st ed. 2019 New York, NY Springer New York 2019 1 Online-Ressource (XV, 331 Seiten) Illustrationen txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 2018 The Rat: A Model Used in Biomedical Research -- Rat Genome Assemblies, Annotation, and Variant Repository -- Rat Genome Databases, Repositories, and Tools -- Next Generation Transgenic Rat Model Production -- Embryonic Stem Cells and Gene Manipulation in Rat -- Protocols for Cryopreservation and Rederivation of Rat Gametes -- Fluorescent Imaging and Microscopy for Dynamic Processes in Rats -- Library Preparation for Multiplexed Reduced Representation Bisulfite Sequencing with a Universal Adapter -- Characterization of the Rat Gut Microbiota via 16S rRNA Amplicon Library Sequencing -- Networking in Biology: The Hybrid Rat Diversity Panel -- Using Heterogeneous Stocks for Fine-Mapping Genetically Complex Traits -- Mapping Mammary Tumor Traits in the Rat -- Rat Models of Metabolic Syndrome -- Genomic Research in Rat Models of Kidney Disease -- Rat Models of Exercise for the Study of Complex Disease -- Behavioral Genetic Studies in Rats This book provides both historical perspective and practical information to support researchers either currently involved in genomic research on rats or planning to begin such a project. In numerous chapters, a detailed protocol is provided for researchers looking to move into a new area of investigation or to leverage a new technology. In other cases, a detailed review of existing models or a description of available resources can help the researcher find, understand, and utilize the information, the data, and the tools that they need to support their research efforts. Written as part of the highly successful Methods in Molecular Biology series, this collection includes the kind of hands-on detail necessary for success in the lab. Authoritative and up-to-date, Rat Genomics explores the rat as a biomedical model uniquely poised to provide the ideal combination of established experimental models, extensive physiological data, and genomic manipulability to facilitate exploration of the underlying biology Animal genetics Animal models in research Hayman, G. Thomas ca. 20./21. Jh. (DE-588)1247765342 edt Smith, Jennifer R. ca. 20./21. Jh. (DE-588)124776561X edt Dwinell, Melinda R. ca. 20./21. Jh. (DE-588)1247766136 edt Shimoyama, Mary ca. 20./21. Jh. (DE-588)1247766284 edt Erscheint auch als Druck-Ausgabe 978-1-4939-9583-7 https://doi.org/10.1007/978-1-4939-9581-3 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Rat genomics Animal genetics Animal models in research |
| title | Rat genomics |
| title_auth | Rat genomics |
| title_exact_search | Rat genomics |
| title_exact_search_txtP | Rat genomics |
| title_full | Rat genomics edited by G. Thomas Hayman, Jennifer R. Smith, Melinda R. Dwinell, Mary Shimoyama |
| title_fullStr | Rat genomics edited by G. Thomas Hayman, Jennifer R. Smith, Melinda R. Dwinell, Mary Shimoyama |
| title_full_unstemmed | Rat genomics edited by G. Thomas Hayman, Jennifer R. Smith, Melinda R. Dwinell, Mary Shimoyama |
| title_short | Rat genomics |
| title_sort | rat genomics |
| topic | Animal genetics Animal models in research |
| topic_facet | Animal genetics Animal models in research |
| url | https://doi.org/10.1007/978-1-4939-9581-3 |
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