Clinical immunology:
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Weitere Verfasser: | |
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Oxford
Oxford University Press
[2016]
|
| Ausgabe: | Second edition |
| Schriftenreihe: | Fundamentals of biomedical science
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | XIII, 345 Seiten Illustrationen, Diagramme |
| ISBN: | 9780199657650 |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV043216640 | ||
| 003 | DE-604 | ||
| 005 | 20160812 | ||
| 007 | t | ||
| 008 | 151216s2016 a||| |||| 00||| eng d | ||
| 020 | |a 9780199657650 |9 978-0-19-965765-0 | ||
| 020 | |z 0199657653 |9 0-19-965765-3 | ||
| 035 | |a (OCoLC)950934532 | ||
| 035 | |a (DE-599)BVBBV043216640 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 |a DE-29 |a DE-578 | ||
| 082 | 0 | |a 616.079 |2 23 | |
| 084 | |a XD 2801 |0 (DE-625)152549:12907 |2 rvk | ||
| 084 | |a QW 504 |2 nlm | ||
| 245 | 1 | 0 | |a Clinical immunology |c edited by Angela Hall, Chris Scott, Matthew Buckland |
| 250 | |a Second edition | ||
| 264 | 1 | |a Oxford |b Oxford University Press |c [2016] | |
| 264 | 4 | |c © 2016 | |
| 300 | |a XIII, 345 Seiten |b Illustrationen, Diagramme | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Fundamentals of biomedical science | |
| 650 | 0 | 7 | |a Immunologie |0 (DE-588)4026637-0 |2 gnd |9 rswk-swf |
| 655 | 7 | |0 (DE-588)4123623-3 |a Lehrbuch |2 gnd-content | |
| 689 | 0 | 0 | |a Immunologie |0 (DE-588)4026637-0 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Hall, Angela |d 1962- |0 (DE-588)140070397 |4 edt |4 aut | |
| 700 | 1 | |a Scott, Chris |4 edt |4 aut | |
| 700 | 1 | |a Buckland, Matthew |4 edt | |
| 856 | 4 | 2 | |m Digitalisierung UB Regensburg - ADAM Catalogue Enrichment |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028639663&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 856 | 4 | 2 | |m Digitalisierung UB Regensburg - ADAM Catalogue Enrichment |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028639663&sequence=000002&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |3 Klappentext |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-028639663 | ||
Datensatz im Suchindex
| _version_ | 1804175721850994688 |
|---|---|
| adam_text | CCHA ttV S.
Introduction to the Clinical 3.13 Flow cytometric basophil activation test 63
Immunology laboratory 1 3.14 Measurement of mediators released
Angela Hall and Chris Baldwin during allergic reactions 68
Introduction 1 3.15 IgG antibodies in hypersensitivity 71
i.i Immunology 2 Chapter summary 73
1.2 Immunology in biomedical science 3 Further reading 73
Chapter summary 5 Discussion questions 74
Discussion questions 5 4 Complement 75
2 Immunoglobulins Lynn Follows and Phillip A Whitfield Introduction 6 Mo Moody, Tariq El-Shanawany, Paul Williams, B Paul Morgan, and Stephen Jolles
6
2.1 Immunoglobulins 6 Introduction 75
2.2 The monoclonal gammopathies 12 4.1 Actions of complement 76
2.3 Quantification of immunoglobulins 14 4.2 Regulation of complement 79
2.4 Cerebrospinal fluid and isoelectric 4.3 Complement deficiencies 80
focusing 33 4.4 Measurement of complement activity 84
2.5 Cryoglobulins 37 4.5 Cl inhibitor deficiency 91
Chapter summary 40 4.6 Auto-antibodies against complement
Further reading 41 components and complexes 95
Discussion questions 42 4.7 Complement allotyping 96
4.8 Molecular testing for complement
3 Allergy 43 deficiencies 96
Kirsty Swallow Chapter summary 97
Introduction 43 Further reading 97
3.1 Allergy terminology 43 Discussion questions 98
3.2 Allergens 44 Autoimmune rheumatological disease
3.3 Allergy mechanisms 45 5 99
3.4 Clinical features of allergic diseases 46 Chris Scott
3.5 Clinical diagnosis 49
3.6 Allergen-specific IgE tests 53 Introduction 99
3.7 Allergen standardization 54 5.1 Systemic lupus erythematosus (SLE) 100
3.8 Cross-reactivity 55 5.2 Rheumatoid arthritis (RA) 102
3.9 Component resolved diagnostics 57 5.3 Scleroderma 105
3.10 Microarray-based allergy testing 59 5.4 Sjogren s syndrome 107
3.11 Total IgE measurements 61 5.5 Polymyositis and dermatomyositis 107
3.12 Quality assurance of laboratory allergy 5.6 Antiphospholipid syndrome (APS) 107
tests 62 5.7 Overlapping connective tissue diseases 109
XII
CONTENTS
5.8 Auto-antibodies 110 8.2
Chapter summary 118 8.3
Further reading 118 8.4
Discussion questions 119
6 Autoimmune kidney disease Angela Hall 120
Introduction 120
6.1 Vasculitis and classification 121 Q
6.2 Microscopic polyangiitis (MPA) 123 y
6.3 Granulomatosis with polyangiitis (Wegener s) (GPA) 124
6.4 Eosinophilic granulomatosis with 9.1
polyangiitis (Churg-Strauss) (EGPA) 124 9.2
6.5 Anti-GBM disease (Goodpasture s 9.3
syndrome) 125 9.4
6.6 Membranous nephropathy (MN) 125 9.5
6.7 Pathogenesis of renal related auto-antibodies 126
6.8 Treatment and prognosis of autoimmune renal disease 127
6.9 Auto-antibodies in autoimmune kidney diseases 128
C/itipit’f summary 137 10
Further reading 138
Discussion questions 138 10.1
7 Organ-specific autoimmunity 139 10.2
Robert J Lock 10.3
Introduction 139 10.4
7.1 Autoimmune thyroid disease 141
7.2 Coeliac disease 148 10.5
7.3 Pernicious anaemia 156
7.4 Autoimmune endocrinopathies 159 10.6
Chapter su mm ary 168
Further reading 168 10.7
Discussion questions 169 10.8
8 Autoimmune skin disease Robert J Lock, Sarah Johnston, and Philip Bright 170 10.9
Introduction 170
8.1 Skin structure 171
Pemphigoid diseases Pemphigus diseases
Other autoimmune blistering skin disorders
Chapter summary Acknowledgements Further reading Discussion questions
Autoimmune liver diseases
Edward Davies
Introduction
Autoimmune hepatitis (AIH) Autoimmune sclerosing cholangitis (ASC) Primary biliary cirrhosis (PBC)
Overlap syndromes Technical notes Chapter summary Further reading Discussion questions
Neuroimmunology
Abid R Karim and S Jacob
Introduction
Terminology
Epidemiology
Clinical features of paraneoplastic syndromes
Malignancies commonly associated with PNS
Paraneoplastic neurological antibodies (PNA)
Wei I-characterized paraneoplastic antibodies
Partially characterized paraneoplastic antibodies
Pathogenic antibodies with or without cancer
Miscellaneous antibodies
Chapter summary Further reading Discussion questions
172
177
183
186
187
187
187
188
188
189
197
199
204
206
208
209
209
210
210 213
213
214
221
221
226
234
238
245
250
250
251
CONTENTS
XII!
11 Flow cytometry and primary
immunodeficiency Dawn Barge 252
Introduction 252
11.1 Lymphocyte subsets 253
11.2 T cells 258
11.3 B cells 264
11.4 Natural killer (NK) cells 266
11.5 Additional antibodies 267
11.6 Inducible antigens 270
11.7 Intracellular staining 273
11.8 Functional assays 273
11.9 Neutrophil defects 275
Chapter summary 280
Further reading 281
Discussion questions 281
12 Human immunodeficiency
virus (HIV) Alison Cox 282
Introduction 282
12.1 The human immunodeficiency virus 283
12.2 The life cycle of HIV 283
12.3 Transmission of HIV 285
12.4 Effects of HIV on the immune system 285
12.5 Clinical features of HIV infection 286
12.6 Progression to AIDS 287
12.7 Laboratory diagnosis of HIV infection 288
12.8 Treatment regimens for HIV-1 infections 292
12.9 Prevention of HIV transmission and
infection 295
Chapter summary 298
Discussion questions 298
13 Histocompatibility and
immunogenetics David Wilson and Vaughan Carter 299
Introduction 299
13.1 The major histocompatibility
complex (MHC) 300
13.2 HLA system 301
13.3 HLA typing 303
13.4 HLA antibody testing 305
13.5 Solid organ transplantation 306
13.6 Post-transplant monitoring 313
13.7 Haematopoietic progenitor cell
transplantation 314
13.8 HLA and disease 314
Chapter nummary 318
Acknowledgements 319
Discussion questions 319
References 321
Glossary 327
Abbreviations 331
Hints and tips for discussion questions 333
Index 339
The IBMS-endoised FUNDAMENTAIS Of BIOMEDICAL SCIENCE series is written specifically to help you master the competencies required to become a fully proficient biomedical or clinical scientist. Titles in the series cover
all the essential biomedical disciplines—from clínica
oiochemistry to immuno each one seamless
ion science—with science
theory with biomedical science practice.
New to this edition:
Case studies have been extended to help foster an understanding of the diagnostic process, taking you through each clinical case from initial presentation to the interpretation of results.
A new chapter on autoimmune skin disorders explains the clinica features of these diseases, the assays and techniques used to test for them, and common methods of treatment.
A new chapter on histocompatibility and immunogenetics describes the human leukocyte antigen (HLA) system and its role in transplantation and disease, and introduces methods used in the clinical H l laboratory.
|
| any_adam_object | 1 |
| author | Hall, Angela 1962- Scott, Chris |
| author2 | Hall, Angela 1962- Scott, Chris Buckland, Matthew |
| author2_role | edt edt edt |
| author2_variant | a h ah c s cs m b mb |
| author_GND | (DE-588)140070397 |
| author_facet | Hall, Angela 1962- Scott, Chris Hall, Angela 1962- Scott, Chris Buckland, Matthew |
| author_role | aut aut |
| author_sort | Hall, Angela 1962- |
| author_variant | a h ah c s cs |
| building | Verbundindex |
| bvnumber | BV043216640 |
| classification_rvk | XD 2801 |
| ctrlnum | (OCoLC)950934532 (DE-599)BVBBV043216640 |
| dewey-full | 616.079 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.079 |
| dewey-search | 616.079 |
| dewey-sort | 3616.079 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | Second edition |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01879nam a2200433 c 4500</leader><controlfield tag="001">BV043216640</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20160812 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">151216s2016 a||| |||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780199657650</subfield><subfield code="9">978-0-19-965765-0</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="z">0199657653</subfield><subfield code="9">0-19-965765-3</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)950934532</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV043216640</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield><subfield code="a">DE-29</subfield><subfield code="a">DE-578</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">616.079</subfield><subfield code="2">23</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">XD 2801</subfield><subfield code="0">(DE-625)152549:12907</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">QW 504</subfield><subfield code="2">nlm</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Clinical immunology</subfield><subfield code="c">edited by Angela Hall, Chris Scott, Matthew Buckland</subfield></datafield><datafield tag="250" ind1=" " ind2=" "><subfield code="a">Second edition</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Oxford</subfield><subfield code="b">Oxford University Press</subfield><subfield code="c">[2016]</subfield></datafield><datafield tag="264" ind1=" " ind2="4"><subfield code="c">© 2016</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XIII, 345 Seiten</subfield><subfield code="b">Illustrationen, Diagramme</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Fundamentals of biomedical science</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Immunologie</subfield><subfield code="0">(DE-588)4026637-0</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4123623-3</subfield><subfield code="a">Lehrbuch</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Immunologie</subfield><subfield code="0">(DE-588)4026637-0</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hall, Angela</subfield><subfield code="d">1962-</subfield><subfield code="0">(DE-588)140070397</subfield><subfield code="4">edt</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Scott, Chris</subfield><subfield code="4">edt</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Buckland, Matthew</subfield><subfield code="4">edt</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">Digitalisierung UB Regensburg - ADAM Catalogue Enrichment</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028639663&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">Digitalisierung UB Regensburg - ADAM Catalogue Enrichment</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028639663&sequence=000002&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Klappentext</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-028639663</subfield></datafield></record></collection> |
| genre | (DE-588)4123623-3 Lehrbuch gnd-content |
| genre_facet | Lehrbuch |
| id | DE-604.BV043216640 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T07:20:48Z |
| institution | BVB |
| isbn | 9780199657650 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-028639663 |
| oclc_num | 950934532 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-29 DE-578 |
| owner_facet | DE-355 DE-BY-UBR DE-29 DE-578 |
| physical | XIII, 345 Seiten Illustrationen, Diagramme |
| publishDate | 2016 |
| publishDateSearch | 2016 |
| publishDateSort | 2016 |
| publisher | Oxford University Press |
| record_format | marc |
| series2 | Fundamentals of biomedical science |
| spelling | Clinical immunology edited by Angela Hall, Chris Scott, Matthew Buckland Second edition Oxford Oxford University Press [2016] © 2016 XIII, 345 Seiten Illustrationen, Diagramme txt rdacontent n rdamedia nc rdacarrier Fundamentals of biomedical science Immunologie (DE-588)4026637-0 gnd rswk-swf (DE-588)4123623-3 Lehrbuch gnd-content Immunologie (DE-588)4026637-0 s DE-604 Hall, Angela 1962- (DE-588)140070397 edt aut Scott, Chris edt aut Buckland, Matthew edt Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028639663&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028639663&sequence=000002&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Hall, Angela 1962- Scott, Chris Clinical immunology Immunologie (DE-588)4026637-0 gnd |
| subject_GND | (DE-588)4026637-0 (DE-588)4123623-3 |
| title | Clinical immunology |
| title_auth | Clinical immunology |
| title_exact_search | Clinical immunology |
| title_full | Clinical immunology edited by Angela Hall, Chris Scott, Matthew Buckland |
| title_fullStr | Clinical immunology edited by Angela Hall, Chris Scott, Matthew Buckland |
| title_full_unstemmed | Clinical immunology edited by Angela Hall, Chris Scott, Matthew Buckland |
| title_short | Clinical immunology |
| title_sort | clinical immunology |
| topic | Immunologie (DE-588)4026637-0 gnd |
| topic_facet | Immunologie Lehrbuch |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028639663&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=028639663&sequence=000002&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT hallangela clinicalimmunology AT scottchris clinicalimmunology AT bucklandmatthew clinicalimmunology |