Brain lipids in synaptic function and neurological disease: clues to innovative therapeutic strategies for brain disorders
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Amsterdam
Elsevier/Academic Press
[2015]
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| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | Includes bibliographical references and index Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer's, Creutzfeldt-Jakob's and Parkinson's. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders |
| Beschreibung: | 1 Online-Ressource |
| ISBN: | 9780128004920 0128004924 9780128001110 0128001119 |
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| 245 | 1 | 0 | |a Brain lipids in synaptic function and neurological disease |b clues to innovative therapeutic strategies for brain disorders |c Jacques Fantini, Nouara Yahi |
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| author_facet | Fantini, J. , (Jacques) |
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| dewey-full | 612.8 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
| dewey-raw | 612.8 |
| dewey-search | 612.8 |
| dewey-sort | 3612.8 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
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| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:20:47Z |
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| isbn | 9780128004920 0128004924 9780128001110 0128001119 |
| language | English |
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| spelling | Fantini, J. , (Jacques) Verfasser aut Brain lipids in synaptic function and neurological disease clues to innovative therapeutic strategies for brain disorders Jacques Fantini, Nouara Yahi Amsterdam Elsevier/Academic Press [2015] 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer's, Creutzfeldt-Jakob's and Parkinson's. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders MEDICAL / Physiology bisacsh SCIENCE / Life Sciences / Human Anatomy & Physiology bisacsh Medizin Brain Diseases Alternative treatment Yahi, Nouara Sonstige oth http://www.sciencedirect.com/science/book/9780128001110 Verlag Volltext |
| spellingShingle | Fantini, J. , (Jacques) Brain lipids in synaptic function and neurological disease clues to innovative therapeutic strategies for brain disorders MEDICAL / Physiology bisacsh SCIENCE / Life Sciences / Human Anatomy & Physiology bisacsh Medizin Brain Diseases Alternative treatment |
| title | Brain lipids in synaptic function and neurological disease clues to innovative therapeutic strategies for brain disorders |
| title_auth | Brain lipids in synaptic function and neurological disease clues to innovative therapeutic strategies for brain disorders |
| title_exact_search | Brain lipids in synaptic function and neurological disease clues to innovative therapeutic strategies for brain disorders |
| title_full | Brain lipids in synaptic function and neurological disease clues to innovative therapeutic strategies for brain disorders Jacques Fantini, Nouara Yahi |
| title_fullStr | Brain lipids in synaptic function and neurological disease clues to innovative therapeutic strategies for brain disorders Jacques Fantini, Nouara Yahi |
| title_full_unstemmed | Brain lipids in synaptic function and neurological disease clues to innovative therapeutic strategies for brain disorders Jacques Fantini, Nouara Yahi |
| title_short | Brain lipids in synaptic function and neurological disease |
| title_sort | brain lipids in synaptic function and neurological disease clues to innovative therapeutic strategies for brain disorders |
| title_sub | clues to innovative therapeutic strategies for brain disorders |
| topic | MEDICAL / Physiology bisacsh SCIENCE / Life Sciences / Human Anatomy & Physiology bisacsh Medizin Brain Diseases Alternative treatment |
| topic_facet | MEDICAL / Physiology SCIENCE / Life Sciences / Human Anatomy & Physiology Medizin Brain Diseases Alternative treatment |
| url | http://www.sciencedirect.com/science/book/9780128001110 |
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