Solid-phase synthesis of nitrogenous heterocycles:
The five chapters in this book describe different facets of SP (solid phase) heterocycle synthesis. The first chapter by Greg A. Slough is included to inspire novices in SP synthesis and describes details of each of the SP synthesis aspect. He has proven that SP synthesis can be carried out in any o...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Cham
Springer
[2017]
|
| Schriftenreihe: | Topics in heterocyclic chemistry
52 |
| Schlagworte: | |
| Zusammenfassung: | The five chapters in this book describe different facets of SP (solid phase) heterocycle synthesis. The first chapter by Greg A. Slough is included to inspire novices in SP synthesis and describes details of each of the SP synthesis aspect. He has proven that SP synthesis can be carried out in any organic chemistry laboratory, without significant investment, using a plastic syringe equipped with a porous disc served as a reaction vessel for manual SP synthesis. Veronika Fülöpová and Miroslav Soural summarize the rich literature dedicated to the synthesis of seven-membered nitrogenous heterocycles including notoriously known pharmacophores such as benzodiazepines. This chapter shows that numerous different routes are applicable for SP synthesis of the same type of heterocycle, and chemists can select a route best suited for a given project’s needs. Morten Meldal’s laboratory dedicates substantial effort to developing very powerful cyclic iminium – nucleophilic addition cascade reactions. Together with Frederik Diness and Yuanyuan Wang as co-authors they contribute a chapter documenting the power of this cascade reaction for SP synthesis of diverse fused and bridged molecular scaffolds applicable as peptidomimetics. Agustina La-Venia, Carina M. L. Delpiccolo and Ernesto G. Mata focus on methodology and their chapter discusses metal-mediated synthesis of heterocyclic compounds. This area, in particular, is a growth area in heterocyclic chemistry, and we can expect more critical contributions in coming years. The last contribution by Eva Schütznerová and Viktor Krchňák describes syntheses of diverse nitrogenous heterocycles based on C-arylation reaction of 2-nitrobenzene sulfonamides. Interestingly, these synthetic routes were developed for SP in an arena with no precedents for synthesis in solution. To conclude, individual chapters in this book document that SP synthesis can provide the ultimate solution to very efficient synthesis of structurally diverse heterocyclic compounds. |
| Beschreibung: | Auf dem Buchdeckel: "Extras online" |
| Beschreibung: | ix, 170 Seiten Illustrationen, Diagramme (teilweise farbig) |
| ISBN: | 9783319586151 |
| ISSN: | 1861-9282 |
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| 520 | 8 | |a The five chapters in this book describe different facets of SP (solid phase) heterocycle synthesis. The first chapter by Greg A. Slough is included to inspire novices in SP synthesis and describes details of each of the SP synthesis aspect. He has proven that SP synthesis can be carried out in any organic chemistry laboratory, without significant investment, using a plastic syringe equipped with a porous disc served as a reaction vessel for manual SP synthesis. Veronika Fülöpová and Miroslav Soural summarize the rich literature dedicated to the synthesis of seven-membered nitrogenous heterocycles including notoriously known pharmacophores such as benzodiazepines. This chapter shows that numerous different routes are applicable for SP synthesis of the same type of heterocycle, and chemists can select a route best suited for a given project’s needs. Morten Meldal’s laboratory dedicates substantial effort to developing very powerful cyclic iminium – nucleophilic addition cascade reactions. Together with Frederik Diness and Yuanyuan Wang as co-authors they contribute a chapter documenting the power of this cascade reaction for SP synthesis of diverse fused and bridged molecular scaffolds applicable as peptidomimetics. Agustina La-Venia, Carina M. L. Delpiccolo and Ernesto G. Mata focus on methodology and their chapter discusses metal-mediated synthesis of heterocyclic compounds. This area, in particular, is a growth area in heterocyclic chemistry, and we can expect more critical contributions in coming years. The last contribution by Eva Schütznerová and Viktor Krchňák describes syntheses of diverse nitrogenous heterocycles based on C-arylation reaction of 2-nitrobenzene sulfonamides. Interestingly, these synthetic routes were developed for SP in an arena with no precedents for synthesis in solution. | |
| 520 | 8 | |a To conclude, individual chapters in this book document that SP synthesis can provide the ultimate solution to very efficient synthesis of structurally diverse heterocyclic compounds. | |
| 650 | 4 | |a Chemistry | |
| 650 | 4 | |a Inorganic chemistry | |
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| 650 | 4 | |a Chemical engineering | |
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| 650 | 4 | |a Industrial Chemistry/Chemical Engineering | |
| 650 | 4 | |a Inorganic Chemistry | |
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| 700 | 1 | |a Delpiccolo, Carina M. L. |0 (DE-588)1137069929 |4 ctb | |
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| 830 | 0 | |a Topics in heterocyclic chemistry |v 52 |w (DE-604)BV022215535 |9 52 | |
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| id | DE-604.BV044420240 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T07:52:29Z |
| institution | BVB |
| isbn | 9783319586151 |
| issn | 1861-9282 |
| language | English |
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| physical | ix, 170 Seiten Illustrationen, Diagramme (teilweise farbig) |
| publishDate | 2017 |
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| publisher | Springer |
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| series | Topics in heterocyclic chemistry |
| series2 | Topics in heterocyclic chemistry |
| spelling | Solid-phase synthesis of nitrogenous heterocycles Viktor Krchňák, editor ; with contributions by C.M.L. Delpiccolo [und 10 anderen] Cham Springer [2017] © 2017 ix, 170 Seiten Illustrationen, Diagramme (teilweise farbig) txt rdacontent n rdamedia nc rdacarrier Topics in heterocyclic chemistry 52 1861-9282 Auf dem Buchdeckel: "Extras online" The five chapters in this book describe different facets of SP (solid phase) heterocycle synthesis. The first chapter by Greg A. Slough is included to inspire novices in SP synthesis and describes details of each of the SP synthesis aspect. He has proven that SP synthesis can be carried out in any organic chemistry laboratory, without significant investment, using a plastic syringe equipped with a porous disc served as a reaction vessel for manual SP synthesis. Veronika Fülöpová and Miroslav Soural summarize the rich literature dedicated to the synthesis of seven-membered nitrogenous heterocycles including notoriously known pharmacophores such as benzodiazepines. This chapter shows that numerous different routes are applicable for SP synthesis of the same type of heterocycle, and chemists can select a route best suited for a given project’s needs. Morten Meldal’s laboratory dedicates substantial effort to developing very powerful cyclic iminium – nucleophilic addition cascade reactions. Together with Frederik Diness and Yuanyuan Wang as co-authors they contribute a chapter documenting the power of this cascade reaction for SP synthesis of diverse fused and bridged molecular scaffolds applicable as peptidomimetics. Agustina La-Venia, Carina M. L. Delpiccolo and Ernesto G. Mata focus on methodology and their chapter discusses metal-mediated synthesis of heterocyclic compounds. This area, in particular, is a growth area in heterocyclic chemistry, and we can expect more critical contributions in coming years. The last contribution by Eva Schütznerová and Viktor Krchňák describes syntheses of diverse nitrogenous heterocycles based on C-arylation reaction of 2-nitrobenzene sulfonamides. Interestingly, these synthetic routes were developed for SP in an arena with no precedents for synthesis in solution. To conclude, individual chapters in this book document that SP synthesis can provide the ultimate solution to very efficient synthesis of structurally diverse heterocyclic compounds. Chemistry Inorganic chemistry Organic chemistry Chemical engineering Organic Chemistry Industrial Chemistry/Chemical Engineering Inorganic Chemistry Chemie Krchňák, Viktor (DE-588)1137065125 edt Delpiccolo, Carina M. L. (DE-588)1137069929 ctb Erscheint auch als Online-Ausgabe 978-3-319-58616-8 Topics in heterocyclic chemistry 52 (DE-604)BV022215535 52 |
| spellingShingle | Solid-phase synthesis of nitrogenous heterocycles Topics in heterocyclic chemistry Chemistry Inorganic chemistry Organic chemistry Chemical engineering Organic Chemistry Industrial Chemistry/Chemical Engineering Inorganic Chemistry Chemie |
| title | Solid-phase synthesis of nitrogenous heterocycles |
| title_auth | Solid-phase synthesis of nitrogenous heterocycles |
| title_exact_search | Solid-phase synthesis of nitrogenous heterocycles |
| title_full | Solid-phase synthesis of nitrogenous heterocycles Viktor Krchňák, editor ; with contributions by C.M.L. Delpiccolo [und 10 anderen] |
| title_fullStr | Solid-phase synthesis of nitrogenous heterocycles Viktor Krchňák, editor ; with contributions by C.M.L. Delpiccolo [und 10 anderen] |
| title_full_unstemmed | Solid-phase synthesis of nitrogenous heterocycles Viktor Krchňák, editor ; with contributions by C.M.L. Delpiccolo [und 10 anderen] |
| title_short | Solid-phase synthesis of nitrogenous heterocycles |
| title_sort | solid phase synthesis of nitrogenous heterocycles |
| topic | Chemistry Inorganic chemistry Organic chemistry Chemical engineering Organic Chemistry Industrial Chemistry/Chemical Engineering Inorganic Chemistry Chemie |
| topic_facet | Chemistry Inorganic chemistry Organic chemistry Chemical engineering Organic Chemistry Industrial Chemistry/Chemical Engineering Inorganic Chemistry Chemie |
| volume_link | (DE-604)BV022215535 |
| work_keys_str_mv | AT krchnakviktor solidphasesynthesisofnitrogenousheterocycles AT delpiccolocarinaml solidphasesynthesisofnitrogenousheterocycles |