Metallo-drugs :: development and action of anticancer agents /
Volume 18 centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by...
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| Weitere Verfasser: | , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Berlin ; Boston :
Walter de Gruyter GmbH,
[2018]
|
| Schriftenreihe: | Metal ions in life sciences ;
v. 18. |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | Volume 18 centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity, initiated research on polynuclear platinum complexes and on Pt(IV) complexes as prodrugs. Furthermore, the indicated shortcomings led to the exploration of other transition and main group metal ions, among them Ru(II/III), Au(I/III), Ti(IV), V(IV/V), and Ga(III) including also the essential metal ions Fe(II/III), Cu(I/II), and Zn(II). Ionic as well as covalent and non-covalent interactions between structurally very different complexes and biomolecules like nucleic acids, proteins, and carbohydrates are studied and discussed with regard to their possible anticancer actions. Hence, MILS-18 summarizes the research at the forefront of medicinal inorganic chemistry, including studies on the next-generation, tailor-made anticancer drugs. All this and more is treated in an authoritative and timely manner in the 17 stimulating chapters of this book, written by 39 internationally recognized experts from 10 nations (from the US via Europe to China and Australia). The impact of this vibrant research area is manifested by more than 2700 references, nearly 150 illustrations (more than half in color) and several comprehensive tables. Metallo-Drugs: Development and Action of Anticancer Agents is an essential resource for scientists working in the wide range from enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching. |
| Beschreibung: | 1 online resource (588 pages) |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9783110470734 311047073X 9783110470741 3110470748 3110469901 9783110469905 |
| ISSN: | 1559-0836 ; |
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| 245 | 0 | 0 | |a Metallo-drugs : |b development and action of anticancer agents / |c edited by Astrid Sigel, Helmut Sigel, Eva Freisinger, and Roland K.O. Sigel. |
| 264 | 1 | |a Berlin ; |a Boston : |b Walter de Gruyter GmbH, |c [2018] | |
| 264 | 4 | |c ©2018 | |
| 300 | |a 1 online resource (588 pages) | ||
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| 490 | 1 | |a Metal ions in life sciences, |x 1559-0836 ; |v volume 18 | |
| 505 | 0 | 0 | |g About the editors -- |g Historical development and perspectives of the series / |r Astrid Sigel, Helmut Sigel, Roland K.O. Sigel -- |g Preface to volume 18 / |r Astrid Sigel, Helmut Sigel, Eva Freisinger, Roland K.O. Sigel -- |g Contributors to volume 18. -- |g 1. |t Cisplatin and oxaliplatin : our current understanding of their actions / |r Imogen A. Riddell, Stephen J. Lippard -- |g 2. |t Polynuclear platinum complexes : structural diversity and DNA binding / |r Viktor Brabec, Jana Kasparkova, Vijay Menon, Nicholas P. Farrell -- |g 3. |t Platinum(IV) prodrugs / |r V. Venkatesh, Peter J. Sadler -- |g 4. |t Metalloglycomics / |r Nicholas P. Farrell, Anil K. Gorle, Erica J. Peterson, Susan J. Berners-Price -- |g 5. |t The deceptively similar ruthenium(III) drug candidates KP1019 and NAMI-A have different actions : what did we learn in the past 30 years? / |r Enzo Alessio, Luigi Messori -- |g 6. |t Multinuclear organometallic ruthenium-arene complexes for cancer therapy / |r Maria V. Babak, Wee Han Ang -- |g 7. |t Medicinal chemistry of gold anticancer metallodrugs / |r Angela Casini, Raymond Wai-Yin Sun, Ingo Ott -- |g 8. |t Coordination complexes of titanium(IV) for anticancer therapy / |r Edit Y. Tshuva, Maya Miller -- |g 9. |t Health benefits of vanadium and its potential as an anticancer agent / |r Debbie C. Crans, Lining Yang, Allison Haase, Xiaogai Yang -- |g 10. |t Gallium complexes as anticancer drugs / |r Christopher R. Chitambar -- |g 11. |t Non-covalent metallo-drugs : using shape to target DNA and RNA junctions and other nucleic acid structures / |r Lucia Cardo, Michael J. Lucia -- |g 12. |t Nucleic acid quadruplexes and metallo-drugs / |r Ramon Vilar -- |g 13. |t Antitumor metallodrugs that target proteins / |r Matthew P. Sullivan, Hannah U. Holtkamp, Christian G. Hartinger -- |g 14. |t Metallointercalators and metalloinsertors : structural requirements for DNA recognition and anticancer activity / |r Ulrich Schatzschneider -- |g 15. |t Iron and its role in cancer defense : a double-edged sword / |r Frank Thévenod -- |g 16. |t Copper complexes in cancer therapy / |r Delphine Denoyer, Sharnel A.S. Clatworthy, Michael A. Cater -- |g 17. |t Targeting zinc(II) signalling to prevent cancer / |r Silvia Ziliotto, Olivia Ogle,Kathryn M. Taylor -- |g Subject index. |
| 520 | |a Volume 18 centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity, initiated research on polynuclear platinum complexes and on Pt(IV) complexes as prodrugs. Furthermore, the indicated shortcomings led to the exploration of other transition and main group metal ions, among them Ru(II/III), Au(I/III), Ti(IV), V(IV/V), and Ga(III) including also the essential metal ions Fe(II/III), Cu(I/II), and Zn(II). Ionic as well as covalent and non-covalent interactions between structurally very different complexes and biomolecules like nucleic acids, proteins, and carbohydrates are studied and discussed with regard to their possible anticancer actions. Hence, MILS-18 summarizes the research at the forefront of medicinal inorganic chemistry, including studies on the next-generation, tailor-made anticancer drugs. All this and more is treated in an authoritative and timely manner in the 17 stimulating chapters of this book, written by 39 internationally recognized experts from 10 nations (from the US via Europe to China and Australia). The impact of this vibrant research area is manifested by more than 2700 references, nearly 150 illustrations (more than half in color) and several comprehensive tables. Metallo-Drugs: Development and Action of Anticancer Agents is an essential resource for scientists working in the wide range from enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching. | ||
| 546 | |a In English. | ||
| 588 | 0 | |a Online resource; title from PDF title page (publisher's Web site, viewed 19. Feb 2018). | |
| 504 | |a Includes bibliographical references and index. | ||
| 650 | 0 | |a Organoplatinum compounds |x Therapeutic use. | |
| 650 | 0 | |a Antineoplastic agents. |0 http://id.loc.gov/authorities/subjects/sh85005714 | |
| 650 | 0 | |a Pharmaceutical chemistry. |0 http://id.loc.gov/authorities/subjects/sh85023026 | |
| 650 | 0 | |a Cisplatin. |0 http://id.loc.gov/authorities/subjects/sh85026108 | |
| 650 | 1 | 2 | |a Organoplatinum Compounds |x therapeutic use |
| 650 | 2 | 2 | |a Antineoplastic Agents |
| 650 | 2 | 2 | |a Cisplatin |
| 650 | 2 | |a Chemistry, Pharmaceutical |0 https://id.nlm.nih.gov/mesh/D002626 | |
| 650 | 6 | |a Composés organoplatiniques |x Emploi en thérapeutique. | |
| 650 | 6 | |a Anticancéreux. | |
| 650 | 6 | |a Chimie pharmaceutique. | |
| 650 | 6 | |a Cisplatine. | |
| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a Cisplatin |2 fast | |
| 650 | 7 | |a Antineoplastic agents |2 fast | |
| 650 | 7 | |a Organoplatinum compounds |x Therapeutic use |2 fast | |
| 650 | 7 | |a Pharmaceutical chemistry |2 fast | |
| 655 | 4 | |a Electronic book. | |
| 700 | 1 | |a Alessio, Enzo. | |
| 700 | 1 | |a Ang, Wee Han. | |
| 700 | 1 | |a Babak, Maria V. | |
| 700 | 1 | |a Berners-Price, Susan. | |
| 700 | 1 | |a Brabec, Victor. | |
| 700 | 1 | |a Casini, A. | |
| 700 | 1 | |a Farrell, Nicholas P. | |
| 700 | 1 | |a Freisinger, Eva, |e editor. | |
| 700 | 1 | |a Gorle, Anil K. | |
| 700 | 1 | |a Kasparkova, Jana. | |
| 700 | 1 | |a Lippard, Stephen J. | |
| 700 | 1 | |a Menon, Vijay. | |
| 700 | 1 | |a Messori, Luigi. | |
| 700 | 1 | |a Peterson, Erica J. | |
| 700 | 1 | |a Riddell, Imogen. | |
| 700 | 1 | |a Sadler, Peter J. | |
| 700 | 1 | |a Sigel, Astrid, |e editor. | |
| 700 | 1 | |a Sigel, Helmut, |e editor. | |
| 700 | 1 | |a Sigel, Roland K. O., |e editor. | |
| 700 | 1 | |a Venkatesh, V. | |
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| _version_ | 1816882414016790528 |
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| author2 | Alessio, Enzo Ang, Wee Han Babak, Maria V. Berners-Price, Susan Brabec, Victor Casini, A. Farrell, Nicholas P. Freisinger, Eva Gorle, Anil K. Kasparkova, Jana Lippard, Stephen J. Menon, Vijay Messori, Luigi Peterson, Erica J. Riddell, Imogen Sadler, Peter J. Sigel, Astrid Sigel, Helmut Sigel, Roland K. O. Venkatesh, V. |
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| author_additional | Astrid Sigel, Helmut Sigel, Roland K.O. Sigel -- Astrid Sigel, Helmut Sigel, Eva Freisinger, Roland K.O. Sigel -- Imogen A. Riddell, Stephen J. Lippard -- Viktor Brabec, Jana Kasparkova, Vijay Menon, Nicholas P. Farrell -- V. Venkatesh, Peter J. Sadler -- Nicholas P. Farrell, Anil K. Gorle, Erica J. Peterson, Susan J. Berners-Price -- Enzo Alessio, Luigi Messori -- Maria V. Babak, Wee Han Ang -- Angela Casini, Raymond Wai-Yin Sun, Ingo Ott -- Edit Y. Tshuva, Maya Miller -- Debbie C. Crans, Lining Yang, Allison Haase, Xiaogai Yang -- Christopher R. Chitambar -- Lucia Cardo, Michael J. Lucia -- Ramon Vilar -- Matthew P. Sullivan, Hannah U. Holtkamp, Christian G. Hartinger -- Ulrich Schatzschneider -- Frank Thévenod -- Delphine Denoyer, Sharnel A.S. Clatworthy, Michael A. Cater -- Silvia Ziliotto, Olivia Ogle,Kathryn M. Taylor -- |
| author_facet | Alessio, Enzo Ang, Wee Han Babak, Maria V. Berners-Price, Susan Brabec, Victor Casini, A. Farrell, Nicholas P. Freisinger, Eva Gorle, Anil K. Kasparkova, Jana Lippard, Stephen J. Menon, Vijay Messori, Luigi Peterson, Erica J. Riddell, Imogen Sadler, Peter J. Sigel, Astrid Sigel, Helmut Sigel, Roland K. O. Venkatesh, V. |
| author_sort | Alessio, Enzo |
| building | Verbundindex |
| bvnumber | localFWS |
| callnumber-first | R - Medicine |
| callnumber-label | RS431 |
| callnumber-raw | RS431.A64 |
| callnumber-search | RS431.A64 |
| callnumber-sort | RS 3431 A64 |
| callnumber-subject | RS - Pharmacy |
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| contents | Cisplatin and oxaliplatin : our current understanding of their actions / Polynuclear platinum complexes : structural diversity and DNA binding / Platinum(IV) prodrugs / Metalloglycomics / The deceptively similar ruthenium(III) drug candidates KP1019 and NAMI-A have different actions : what did we learn in the past 30 years? / Multinuclear organometallic ruthenium-arene complexes for cancer therapy / Medicinal chemistry of gold anticancer metallodrugs / Coordination complexes of titanium(IV) for anticancer therapy / Health benefits of vanadium and its potential as an anticancer agent / Gallium complexes as anticancer drugs / Non-covalent metallo-drugs : using shape to target DNA and RNA junctions and other nucleic acid structures / Nucleic acid quadruplexes and metallo-drugs / Antitumor metallodrugs that target proteins / Metallointercalators and metalloinsertors : structural requirements for DNA recognition and anticancer activity / Iron and its role in cancer defense : a double-edged sword / Copper complexes in cancer therapy / Targeting zinc(II) signalling to prevent cancer / |
| ctrlnum | (OCoLC)1024024707 |
| dewey-full | 615.7/98 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.7/98 |
| dewey-search | 615.7/98 |
| dewey-sort | 3615.7 298 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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Tshuva, Maya Miller --</subfield><subfield code="g">9.</subfield><subfield code="t">Health benefits of vanadium and its potential as an anticancer agent /</subfield><subfield code="r">Debbie C. Crans, Lining Yang, Allison Haase, Xiaogai Yang --</subfield><subfield code="g">10.</subfield><subfield code="t">Gallium complexes as anticancer drugs /</subfield><subfield code="r">Christopher R. Chitambar --</subfield><subfield code="g">11.</subfield><subfield code="t">Non-covalent metallo-drugs : using shape to target DNA and RNA junctions and other nucleic acid structures /</subfield><subfield code="r">Lucia Cardo, Michael J. Lucia --</subfield><subfield code="g">12.</subfield><subfield code="t">Nucleic acid quadruplexes and metallo-drugs /</subfield><subfield code="r">Ramon Vilar --</subfield><subfield code="g">13.</subfield><subfield code="t">Antitumor metallodrugs that target proteins /</subfield><subfield code="r">Matthew P. Sullivan, Hannah U. Holtkamp, Christian G. Hartinger --</subfield><subfield code="g">14.</subfield><subfield code="t">Metallointercalators and metalloinsertors : structural requirements for DNA recognition and anticancer activity /</subfield><subfield code="r">Ulrich Schatzschneider --</subfield><subfield code="g">15.</subfield><subfield code="t">Iron and its role in cancer defense : a double-edged sword /</subfield><subfield code="r">Frank Thévenod --</subfield><subfield code="g">16.</subfield><subfield code="t">Copper complexes in cancer therapy /</subfield><subfield code="r">Delphine Denoyer, Sharnel A.S. Clatworthy, Michael A. Cater --</subfield><subfield code="g">17.</subfield><subfield code="t">Targeting zinc(II) signalling to prevent cancer /</subfield><subfield code="r">Silvia Ziliotto, Olivia Ogle,Kathryn M. Taylor --</subfield><subfield code="g">Subject index.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Volume 18 centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity, initiated research on polynuclear platinum complexes and on Pt(IV) complexes as prodrugs. Furthermore, the indicated shortcomings led to the exploration of other transition and main group metal ions, among them Ru(II/III), Au(I/III), Ti(IV), V(IV/V), and Ga(III) including also the essential metal ions Fe(II/III), Cu(I/II), and Zn(II). Ionic as well as covalent and non-covalent interactions between structurally very different complexes and biomolecules like nucleic acids, proteins, and carbohydrates are studied and discussed with regard to their possible anticancer actions. 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| genre | Electronic book. |
| genre_facet | Electronic book. |
| id | ZDB-4-EBA-on1024024707 |
| illustrated | Not Illustrated |
| indexdate | 2024-11-27T13:28:14Z |
| institution | BVB |
| isbn | 9783110470734 311047073X 9783110470741 3110470748 3110469901 9783110469905 |
| issn | 1559-0836 ; |
| language | English |
| lccn | 2018001061 |
| oclc_num | 1024024707 |
| open_access_boolean | |
| owner | MAIN DE-863 DE-BY-FWS |
| owner_facet | MAIN DE-863 DE-BY-FWS |
| physical | 1 online resource (588 pages) |
| psigel | ZDB-4-EBA |
| publishDate | 2018 |
| publishDateSearch | 2018 |
| publishDateSort | 2018 |
| publisher | Walter de Gruyter GmbH, |
| record_format | marc |
| series | Metal ions in life sciences ; |
| series2 | Metal ions in life sciences, |
| spelling | Metallo-drugs : development and action of anticancer agents / edited by Astrid Sigel, Helmut Sigel, Eva Freisinger, and Roland K.O. Sigel. Berlin ; Boston : Walter de Gruyter GmbH, [2018] ©2018 1 online resource (588 pages) text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Metal ions in life sciences, 1559-0836 ; volume 18 About the editors -- Historical development and perspectives of the series / Astrid Sigel, Helmut Sigel, Roland K.O. Sigel -- Preface to volume 18 / Astrid Sigel, Helmut Sigel, Eva Freisinger, Roland K.O. Sigel -- Contributors to volume 18. -- 1. Cisplatin and oxaliplatin : our current understanding of their actions / Imogen A. Riddell, Stephen J. Lippard -- 2. Polynuclear platinum complexes : structural diversity and DNA binding / Viktor Brabec, Jana Kasparkova, Vijay Menon, Nicholas P. Farrell -- 3. Platinum(IV) prodrugs / V. Venkatesh, Peter J. Sadler -- 4. Metalloglycomics / Nicholas P. Farrell, Anil K. Gorle, Erica J. Peterson, Susan J. Berners-Price -- 5. The deceptively similar ruthenium(III) drug candidates KP1019 and NAMI-A have different actions : what did we learn in the past 30 years? / Enzo Alessio, Luigi Messori -- 6. Multinuclear organometallic ruthenium-arene complexes for cancer therapy / Maria V. Babak, Wee Han Ang -- 7. Medicinal chemistry of gold anticancer metallodrugs / Angela Casini, Raymond Wai-Yin Sun, Ingo Ott -- 8. Coordination complexes of titanium(IV) for anticancer therapy / Edit Y. Tshuva, Maya Miller -- 9. Health benefits of vanadium and its potential as an anticancer agent / Debbie C. Crans, Lining Yang, Allison Haase, Xiaogai Yang -- 10. Gallium complexes as anticancer drugs / Christopher R. Chitambar -- 11. Non-covalent metallo-drugs : using shape to target DNA and RNA junctions and other nucleic acid structures / Lucia Cardo, Michael J. Lucia -- 12. Nucleic acid quadruplexes and metallo-drugs / Ramon Vilar -- 13. Antitumor metallodrugs that target proteins / Matthew P. Sullivan, Hannah U. Holtkamp, Christian G. Hartinger -- 14. Metallointercalators and metalloinsertors : structural requirements for DNA recognition and anticancer activity / Ulrich Schatzschneider -- 15. Iron and its role in cancer defense : a double-edged sword / Frank Thévenod -- 16. Copper complexes in cancer therapy / Delphine Denoyer, Sharnel A.S. Clatworthy, Michael A. Cater -- 17. Targeting zinc(II) signalling to prevent cancer / Silvia Ziliotto, Olivia Ogle,Kathryn M. Taylor -- Subject index. Volume 18 centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity, initiated research on polynuclear platinum complexes and on Pt(IV) complexes as prodrugs. Furthermore, the indicated shortcomings led to the exploration of other transition and main group metal ions, among them Ru(II/III), Au(I/III), Ti(IV), V(IV/V), and Ga(III) including also the essential metal ions Fe(II/III), Cu(I/II), and Zn(II). Ionic as well as covalent and non-covalent interactions between structurally very different complexes and biomolecules like nucleic acids, proteins, and carbohydrates are studied and discussed with regard to their possible anticancer actions. Hence, MILS-18 summarizes the research at the forefront of medicinal inorganic chemistry, including studies on the next-generation, tailor-made anticancer drugs. All this and more is treated in an authoritative and timely manner in the 17 stimulating chapters of this book, written by 39 internationally recognized experts from 10 nations (from the US via Europe to China and Australia). The impact of this vibrant research area is manifested by more than 2700 references, nearly 150 illustrations (more than half in color) and several comprehensive tables. Metallo-Drugs: Development and Action of Anticancer Agents is an essential resource for scientists working in the wide range from enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching. In English. Online resource; title from PDF title page (publisher's Web site, viewed 19. Feb 2018). Includes bibliographical references and index. Organoplatinum compounds Therapeutic use. Antineoplastic agents. http://id.loc.gov/authorities/subjects/sh85005714 Pharmaceutical chemistry. http://id.loc.gov/authorities/subjects/sh85023026 Cisplatin. http://id.loc.gov/authorities/subjects/sh85026108 Organoplatinum Compounds therapeutic use Antineoplastic Agents Cisplatin Chemistry, Pharmaceutical https://id.nlm.nih.gov/mesh/D002626 Composés organoplatiniques Emploi en thérapeutique. Anticancéreux. Chimie pharmaceutique. Cisplatine. MEDICAL Pharmacology. bisacsh Cisplatin fast Antineoplastic agents fast Organoplatinum compounds Therapeutic use fast Pharmaceutical chemistry fast Electronic book. Alessio, Enzo. Ang, Wee Han. Babak, Maria V. Berners-Price, Susan. Brabec, Victor. Casini, A. Farrell, Nicholas P. Freisinger, Eva, editor. Gorle, Anil K. Kasparkova, Jana. Lippard, Stephen J. Menon, Vijay. Messori, Luigi. Peterson, Erica J. Riddell, Imogen. Sadler, Peter J. Sigel, Astrid, editor. Sigel, Helmut, editor. Sigel, Roland K. O., editor. Venkatesh, V. EPUB 9783110469905 Print version: 9783110469844 (DLC) 2018001061 (OCoLC)1019838900 Metal ions in life sciences ; v. 18. 1559-0836 http://id.loc.gov/authorities/names/n2005184640 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1710663 Volltext |
| spellingShingle | Metallo-drugs : development and action of anticancer agents / Metal ions in life sciences ; Cisplatin and oxaliplatin : our current understanding of their actions / Polynuclear platinum complexes : structural diversity and DNA binding / Platinum(IV) prodrugs / Metalloglycomics / The deceptively similar ruthenium(III) drug candidates KP1019 and NAMI-A have different actions : what did we learn in the past 30 years? / Multinuclear organometallic ruthenium-arene complexes for cancer therapy / Medicinal chemistry of gold anticancer metallodrugs / Coordination complexes of titanium(IV) for anticancer therapy / Health benefits of vanadium and its potential as an anticancer agent / Gallium complexes as anticancer drugs / Non-covalent metallo-drugs : using shape to target DNA and RNA junctions and other nucleic acid structures / Nucleic acid quadruplexes and metallo-drugs / Antitumor metallodrugs that target proteins / Metallointercalators and metalloinsertors : structural requirements for DNA recognition and anticancer activity / Iron and its role in cancer defense : a double-edged sword / Copper complexes in cancer therapy / Targeting zinc(II) signalling to prevent cancer / Organoplatinum compounds Therapeutic use. Antineoplastic agents. http://id.loc.gov/authorities/subjects/sh85005714 Pharmaceutical chemistry. http://id.loc.gov/authorities/subjects/sh85023026 Cisplatin. http://id.loc.gov/authorities/subjects/sh85026108 Organoplatinum Compounds therapeutic use Antineoplastic Agents Cisplatin Chemistry, Pharmaceutical https://id.nlm.nih.gov/mesh/D002626 Composés organoplatiniques Emploi en thérapeutique. Anticancéreux. Chimie pharmaceutique. Cisplatine. MEDICAL Pharmacology. bisacsh Cisplatin fast Antineoplastic agents fast Organoplatinum compounds Therapeutic use fast Pharmaceutical chemistry fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85005714 http://id.loc.gov/authorities/subjects/sh85023026 http://id.loc.gov/authorities/subjects/sh85026108 https://id.nlm.nih.gov/mesh/D002626 |
| title | Metallo-drugs : development and action of anticancer agents / |
| title_alt | Cisplatin and oxaliplatin : our current understanding of their actions / Polynuclear platinum complexes : structural diversity and DNA binding / Platinum(IV) prodrugs / Metalloglycomics / The deceptively similar ruthenium(III) drug candidates KP1019 and NAMI-A have different actions : what did we learn in the past 30 years? / Multinuclear organometallic ruthenium-arene complexes for cancer therapy / Medicinal chemistry of gold anticancer metallodrugs / Coordination complexes of titanium(IV) for anticancer therapy / Health benefits of vanadium and its potential as an anticancer agent / Gallium complexes as anticancer drugs / Non-covalent metallo-drugs : using shape to target DNA and RNA junctions and other nucleic acid structures / Nucleic acid quadruplexes and metallo-drugs / Antitumor metallodrugs that target proteins / Metallointercalators and metalloinsertors : structural requirements for DNA recognition and anticancer activity / Iron and its role in cancer defense : a double-edged sword / Copper complexes in cancer therapy / Targeting zinc(II) signalling to prevent cancer / |
| title_auth | Metallo-drugs : development and action of anticancer agents / |
| title_exact_search | Metallo-drugs : development and action of anticancer agents / |
| title_full | Metallo-drugs : development and action of anticancer agents / edited by Astrid Sigel, Helmut Sigel, Eva Freisinger, and Roland K.O. Sigel. |
| title_fullStr | Metallo-drugs : development and action of anticancer agents / edited by Astrid Sigel, Helmut Sigel, Eva Freisinger, and Roland K.O. Sigel. |
| title_full_unstemmed | Metallo-drugs : development and action of anticancer agents / edited by Astrid Sigel, Helmut Sigel, Eva Freisinger, and Roland K.O. Sigel. |
| title_short | Metallo-drugs : |
| title_sort | metallo drugs development and action of anticancer agents |
| title_sub | development and action of anticancer agents / |
| topic | Organoplatinum compounds Therapeutic use. Antineoplastic agents. http://id.loc.gov/authorities/subjects/sh85005714 Pharmaceutical chemistry. http://id.loc.gov/authorities/subjects/sh85023026 Cisplatin. http://id.loc.gov/authorities/subjects/sh85026108 Organoplatinum Compounds therapeutic use Antineoplastic Agents Cisplatin Chemistry, Pharmaceutical https://id.nlm.nih.gov/mesh/D002626 Composés organoplatiniques Emploi en thérapeutique. Anticancéreux. Chimie pharmaceutique. Cisplatine. MEDICAL Pharmacology. bisacsh Cisplatin fast Antineoplastic agents fast Organoplatinum compounds Therapeutic use fast Pharmaceutical chemistry fast |
| topic_facet | Organoplatinum compounds Therapeutic use. Antineoplastic agents. Pharmaceutical chemistry. Cisplatin. Organoplatinum Compounds therapeutic use Antineoplastic Agents Cisplatin Chemistry, Pharmaceutical Composés organoplatiniques Emploi en thérapeutique. Anticancéreux. Chimie pharmaceutique. Cisplatine. MEDICAL Pharmacology. Antineoplastic agents Organoplatinum compounds Therapeutic use Pharmaceutical chemistry Electronic book. |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1710663 |
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