Neurobiology of addiction and co-morbid disorders:
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Cambridge, MA ; San Diego, CA
Academic Press, an imprint of Elsevier
2021
|
| Ausgabe: | First edition |
| Schriftenreihe: | International review of neurobiology
volume 157 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | xv, 472 Seiten Illustrationen, Diagramme |
| ISBN: | 9780128203552 |
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Datensatz im Suchindex
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| adam_text | Contents Contributors ix The critical importance of understanding comorbidities to effectively treat drug addiction 1. Neurobiological aspects of pain in the context of alcohol use disorder xiii 1 Jessica A. Cucinello-Ragland and Scott Edwards 1. Alcohol use disorder and chronic pain 2. Analgesic actions of alcohol 2 5 3. Medication strategies for treating pain In the context of AUD 10 4. Summary 15 Acknowledgments 17 Disclosure 17 References 17 2. Pain, negative affective states and opioid-based analgesics: Safer pain therapies to dampen addiction 31 Nicolas Massaly, Tamara Markovič, Meaghan Creed, Ream Al-Hasani, Catherine M. Cahill, and Jose A. Moron 1. Introduction: Pain and the opioid epidemic 32 2. Pain and the endogenous opioid system 35 3. Pain-Induced alterations In opioid consumption 44 4. Circuits underlying pain-induced negative affect and OUD 48 5. Development of safer analgesics approaches for chronic pain 52 6. Conclusions 53 References 54 3. The neural, behavioral, and epidemiological underpinnings of comorbid alcohol use disorder and post-traumatic stress disorder 69 Hannah N. Carlson and Jeff L. Weiner 1. Introduction 71 2. The diagnosis of AUD and PTSD 72 v
v¡ Contents 3. Epidemiology of comorbid AUD and PTSD inthe general population 73 4. Epidemiology of AUD and PTSD in vulnerable populations 74 5. Which comes first? 77 6. Clinical consequences of comorbid AUD and PTSD 7. Animal models of comorbid AUD and PTSD 8. Neurobiological substrates of comorbid AUD 79 80 and PTSD 9. Reward circuitry 86 87 10. Stress circuitry 95 11. A novel neural framework for comorbid AUD and PTSD 109 12. Conclusions 121 References 122 4. Cannabis use and posttraumatic stress disorder comorbidity: Epidemiology, biology and the potential for novel treatment approaches 143 Veronika Kondev, Nathan Winters, and Sachin Patel 1. Introduction 144 2. PTSD 147 3. PTSD—Cannabis use comorbidity 150 4. eCB deficiency hypothesis of PTSD susceptibility 153 5. Cannabinoid modulation of neural 158 processesunderlying PTSD 6. Cannabis as treatment for PTSD 167 7. Conclusion 170 References 171 5. Traumatic brain injury and the misuse of alcohol, opioids, and cannabis 195 Alejandra Jacotte-Simancas, Elizabeth A. Fucich, Zachary F. Stielper, and Patricia E. Molina 1. Traumatic brain injury (TBI) 196 2. Alcohol use and TBI 204 3. Opioid use and TBI 211 4. Cannabis use and TBI 220 5. Post֊TBI cognitive dysfunction and substancemisuse 226 6. Summary 227 Acknowledgment 228 References շշց
Contents 6. Depression and substance usedisorders:Clinical comorbidity and shared neurobiology vii 245 Cali A. Calarco and Mary Kay Lobo 1. Introduction 246 2. Neurobiology of depression 249 3. Comorbid depression and addiction 274 4. Stress-induced drug intake 285 5. Withdrawal-induced depression 287 6. Therapeutic challenges for comorbid MDD and SUD 289 7. Conclusion 292 References 292 7. The role of gut-immune-brain signaling insubstance use disorders 311 Kelsey E. Lucerne and Drew D. Király 1. Introduction 313 2. Overview of the immune system 315 3. Neuroimmune signaling 317 4. Neuroimmune mechanisms of addiction 324 5. Mechanisms of gut microbiome-brain signaling 339 6. Gut microbiome and substance use disorders 343 7. Conclusion 349 Acknowledgments 351 Glossary 351 References 352 8. Bidirectional causality betweenaddictionandcognitive deficits 371 Patrick R. Melugin, Suzanne 0. Nolan, and Cody A. Siciliano 1. Introduction 372 2. Cognitive deficits and SUDs: Clinical findings 373 3. Clinical evidence linking executive dysfunction and addiction vulnerability 376 4. Clinical evidence for substance-induced impairments in executive function 378 5. Insights from preclinical models 381 6. Phenotypic predictors of SUD vulnerability in animal models 381 7. Substance-induced impairments in cognitive function in animal models 386 8. Circuit mechanisms of substance-induced cognitive deficits 390 9. Concluding remarks 393 Funding and disclosure 394 References 394
viii Contents 9. Drug addiction co-morbidity with alcohol: Neurobiological insights 409 M. Adrienne McGinn, Caroline B. Pantazis, Brendan J. Tunstall, Renata C.N. Marchette, Erika R. Carlson, Nadia Said, George F. Koob, and Leandro F. Vendruscolo 1. Introduction 2. Epidemiology 410 3. Neurobiologicalinteractions 421 4. Gaps and challenges 446 410 Acknowledgments 447 References 447
|
| adam_txt |
Contents Contributors ix The critical importance of understanding comorbidities to effectively treat drug addiction 1. Neurobiological aspects of pain in the context of alcohol use disorder xiii 1 Jessica A. Cucinello-Ragland and Scott Edwards 1. Alcohol use disorder and chronic pain 2. Analgesic actions of alcohol 2 5 3. Medication strategies for treating pain In the context of AUD 10 4. Summary 15 Acknowledgments 17 Disclosure 17 References 17 2. Pain, negative affective states and opioid-based analgesics: Safer pain therapies to dampen addiction 31 Nicolas Massaly, Tamara Markovič, Meaghan Creed, Ream Al-Hasani, Catherine M. Cahill, and Jose A. Moron 1. Introduction: Pain and the opioid epidemic 32 2. Pain and the endogenous opioid system 35 3. Pain-Induced alterations In opioid consumption 44 4. Circuits underlying pain-induced negative affect and OUD 48 5. Development of safer analgesics approaches for chronic pain 52 6. Conclusions 53 References 54 3. The neural, behavioral, and epidemiological underpinnings of comorbid alcohol use disorder and post-traumatic stress disorder 69 Hannah N. Carlson and Jeff L. Weiner 1. Introduction 71 2. The diagnosis of AUD and PTSD 72 v
v¡ Contents 3. Epidemiology of comorbid AUD and PTSD inthe general population 73 4. Epidemiology of AUD and PTSD in vulnerable populations 74 5. Which comes first? 77 6. Clinical consequences of comorbid AUD and PTSD 7. Animal models of comorbid AUD and PTSD 8. Neurobiological substrates of comorbid AUD 79 80 and PTSD 9. Reward circuitry 86 87 10. Stress circuitry 95 11. A novel neural framework for comorbid AUD and PTSD 109 12. Conclusions 121 References 122 4. Cannabis use and posttraumatic stress disorder comorbidity: Epidemiology, biology and the potential for novel treatment approaches 143 Veronika Kondev, Nathan Winters, and Sachin Patel 1. Introduction 144 2. PTSD 147 3. PTSD—Cannabis use comorbidity 150 4. eCB deficiency hypothesis of PTSD susceptibility 153 5. Cannabinoid modulation of neural 158 processesunderlying PTSD 6. Cannabis as treatment for PTSD 167 7. Conclusion 170 References 171 5. Traumatic brain injury and the misuse of alcohol, opioids, and cannabis 195 Alejandra Jacotte-Simancas, Elizabeth A. Fucich, Zachary F. Stielper, and Patricia E. Molina 1. Traumatic brain injury (TBI) 196 2. Alcohol use and TBI 204 3. Opioid use and TBI 211 4. Cannabis use and TBI 220 5. Post֊TBI cognitive dysfunction and substancemisuse 226 6. Summary 227 Acknowledgment 228 References շշց
Contents 6. Depression and substance usedisorders:Clinical comorbidity and shared neurobiology vii 245 Cali A. Calarco and Mary Kay Lobo 1. Introduction 246 2. Neurobiology of depression 249 3. Comorbid depression and addiction 274 4. Stress-induced drug intake 285 5. Withdrawal-induced depression 287 6. Therapeutic challenges for comorbid MDD and SUD 289 7. Conclusion 292 References 292 7. The role of gut-immune-brain signaling insubstance use disorders 311 Kelsey E. Lucerne and Drew D. Király 1. Introduction 313 2. Overview of the immune system 315 3. Neuroimmune signaling 317 4. Neuroimmune mechanisms of addiction 324 5. Mechanisms of gut microbiome-brain signaling 339 6. Gut microbiome and substance use disorders 343 7. Conclusion 349 Acknowledgments 351 Glossary 351 References 352 8. Bidirectional causality betweenaddictionandcognitive deficits 371 Patrick R. Melugin, Suzanne 0. Nolan, and Cody A. Siciliano 1. Introduction 372 2. Cognitive deficits and SUDs: Clinical findings 373 3. Clinical evidence linking executive dysfunction and addiction vulnerability 376 4. Clinical evidence for substance-induced impairments in executive function 378 5. Insights from preclinical models 381 6. Phenotypic predictors of SUD vulnerability in animal models 381 7. Substance-induced impairments in cognitive function in animal models 386 8. Circuit mechanisms of substance-induced cognitive deficits 390 9. Concluding remarks 393 Funding and disclosure 394 References 394
viii Contents 9. Drug addiction co-morbidity with alcohol: Neurobiological insights 409 M. Adrienne McGinn, Caroline B. Pantazis, Brendan J. Tunstall, Renata C.N. Marchette, Erika R. Carlson, Nadia Said, George F. Koob, and Leandro F. Vendruscolo 1. Introduction 2. Epidemiology 410 3. Neurobiologicalinteractions 421 4. Gaps and challenges 446 410 Acknowledgments 447 References 447 |
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| spelling | Neurobiology of addiction and co-morbid disorders edited by Erin S. Calipari, Ph.D., Nicholas W. Gilpin, Ph.D. First edition Cambridge, MA ; San Diego, CA Academic Press, an imprint of Elsevier 2021 xv, 472 Seiten Illustrationen, Diagramme txt rdacontent n rdamedia nc rdacarrier International review of neurobiology volume 157 Sekundärkrankheit (DE-588)4131705-1 gnd rswk-swf Sucht (DE-588)4058361-2 gnd rswk-swf Neurobiologie (DE-588)4041871-6 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Neurobiologie (DE-588)4041871-6 s Sucht (DE-588)4058361-2 s Sekundärkrankheit (DE-588)4131705-1 s DE-604 Calipari, Erin S. edt Gilpin, Nicholas W. edt Erscheint auch als Online-Ausgabe 978-0-12-820356-9 International review of neurobiology volume 157 (DE-604)BV002534817 157 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032632936&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
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| title | Neurobiology of addiction and co-morbid disorders |
| title_auth | Neurobiology of addiction and co-morbid disorders |
| title_exact_search | Neurobiology of addiction and co-morbid disorders |
| title_exact_search_txtP | Neurobiology of addiction and co-morbid disorders |
| title_full | Neurobiology of addiction and co-morbid disorders edited by Erin S. Calipari, Ph.D., Nicholas W. Gilpin, Ph.D. |
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| title_short | Neurobiology of addiction and co-morbid disorders |
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