Advances in single molecule, real-time (SMRT) sequencing:
PacBio's single-molecule real-time (SMRT) sequencing technology offers important advantages over the short-read DNA sequencing technologies that currently dominate the market. This includes exceptionally long read lengths (20 kb or more), unparalleled consensus accuracy, and the ability to sequ...
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| Other Authors: | , |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Basel ; Beijing ; Wuhan ; Barcelona ; Belgrade
MDPI
[2019]
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| Subjects: | |
| Online Access: | Volltext https://mdpi.com/books/pdfview/book/1798 |
| Summary: | PacBio's single-molecule real-time (SMRT) sequencing technology offers important advantages over the short-read DNA sequencing technologies that currently dominate the market. This includes exceptionally long read lengths (20 kb or more), unparalleled consensus accuracy, and the ability to sequence native, non-amplified DNA molecules. From fungi to insects to humans, long reads are now used to create highly accurate reference genomes by de novo assembly of genomic DNA and to obtain a comprehensive view of transcriptomes through the sequencing of full-length cDNAs. Besides reducing biases, sequencing native DNA also permits the direct measurement of DNA base modifications. Therefore, SMRT sequencing has become an attractive technology in many fields, such as agriculture, basic science, and medical research. The boundaries of SMRT sequencing are continuously being pushed by developments in bioinformatics and sample preparation. This book contains a collection of articles showcasing the latest developments and the breadth of applications enabled by SMRT sequencing technology |
| Item Description: | This is a reprint of articles from the special issue published online in the open access journal Genes |
| Physical Description: | 1 electronic resource (128 pages) |
| ISBN: | 9783039217014 |
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| isbn | 9783039217014 |
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| physical | 1 electronic resource (128 pages) |
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| publishDate | 2019 |
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| publisher | MDPI |
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| spellingShingle | Advances in single molecule, real-time (SMRT) sequencing Sequenzanalyse Chemie (DE-588)4132277-0 gnd Genanalyse (DE-588)4200230-8 gnd |
| subject_GND | (DE-588)4132277-0 (DE-588)4200230-8 |
| title | Advances in single molecule, real-time (SMRT) sequencing |
| title_auth | Advances in single molecule, real-time (SMRT) sequencing |
| title_exact_search | Advances in single molecule, real-time (SMRT) sequencing |
| title_full | Advances in single molecule, real-time (SMRT) sequencing special issue editors Adam Ameur, Matthew S. Hestand |
| title_fullStr | Advances in single molecule, real-time (SMRT) sequencing special issue editors Adam Ameur, Matthew S. Hestand |
| title_full_unstemmed | Advances in single molecule, real-time (SMRT) sequencing special issue editors Adam Ameur, Matthew S. Hestand |
| title_short | Advances in single molecule, real-time (SMRT) sequencing |
| title_sort | advances in single molecule real time smrt sequencing |
| topic | Sequenzanalyse Chemie (DE-588)4132277-0 gnd Genanalyse (DE-588)4200230-8 gnd |
| topic_facet | Sequenzanalyse Chemie Genanalyse |
| url | https://www.doabooks.org/doab?func=fulltext&uiLanguage=en&rid=42642 https://mdpi.com/books/pdfview/book/1798 |
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