Epigenetics:
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Cold Spring Harbor, New York
Cold Spring Harbor Laboratory Press
[2015]
|
| Ausgabe: | Second edition |
| Schlagworte: | |
| Online-Zugang: | Klappentext Inhaltsverzeichnis |
| Beschreibung: | xiv, 984 Seiten Illustrationen |
| ISBN: | 9781936113590 |
Internformat
MARC
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| 245 | 1 | 0 | |a Epigenetics |c editors: C. David Allis [und 4 weitere] |
| 250 | |a Second edition | ||
| 264 | 1 | |a Cold Spring Harbor, New York |b Cold Spring Harbor Laboratory Press |c [2015] | |
| 300 | |a xiv, 984 Seiten |b Illustrationen | ||
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| 650 | 0 | 7 | |a Epigenetik |0 (DE-588)7566079-9 |2 gnd |9 rswk-swf |
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Datensatz im Suchindex
| _version_ | 1816707050200104960 |
|---|---|
| adam_text |
Contents
Preface, ¡x
Acknowledgments,
xiii
1
A Brief History of Epigenetics,
1
Gary
Felsenfeld
2
The Next Generation: Young Scientists Forging Exciting
New Discoveries in Epigenetic Research,
11
The Discovery of Histone Demethylases,
13
Yujiang
Geno
Shi and Yu-ichi Tsukada
Cellular Reprogramming,
16
Kazutoshi Takahashi
IncRNAs: Linking
RNA
to Chromatin,
18
John L.
Rinn
Enhancer RNAs: A Class of Long Noncoding RNAs
Synthesized at Enhancers,
21
Tae-Kyung Kim, Martin
Hemberg,
and Jesse M. Gray
Expanding the Epigenetic Landscape: Novel
Modifications of Cytosine in Genomic
DNA, 24
Skirmantas Kriaucionis and Mamta Tahiliani
Plant Mobile Small RNAs,
27
Patrice Dunoyer, Charles Melnyk,
Attila
Moinar,
and
R.
Keith
Slotkin
CpG Island Chromatin Is Shaped by Recruitment of
ZF-CxxC Proteins,
30
Neil P. Blackledge, John P. Thomson, and Peter J. Skene
Bromodomain and
Extraterminal
Domain Inhibitors
(BETi) for Cancer Therapy: Chemical Modulation of
Chromatm Structure,
33
Jun Qi
Pharmacological Inhibition of Bromodomain-
Containing Proteins in Inflammation,
36
Uwe Schaefer
Histone H3 Mutations in
Pediatrie
Brain Tumors,
40
XiaoyangLiu, Troy A. McEachron, Jeremy
Schwartzentruber, and Gang Wu
Chromosome Folding: Driver or Passenger of
Epigenetic State?,
44
Tom Sexton and Eitan Yaffe
3
Overview and Concepts,
47
С
David Allis,
Marie-Laure
Caparros,
Thomas Jenuwein,
Monika Lachner,
and Danny
Reinberg
4
Writers and Readers of Histone Acetylation: Structure,
Mechanism, and Inhibition,
117
Ronen Marmorstein
and Ming-Ming Zhou
5
Erasers of Histone Acetylation: The Histone Deacetylase
Enzymes,
143
Edward
Seto
and
Minoru
Yoshida
6
Structural and Functional Coordination of
DNA
and
Histone Methylation,
169
Xiaodong Cheng
7
A Structural Perspective on Readout of Epigenetic
Histone and
DNA
Methylation Marks,
193
DinshawJ.
Patel
8
Epigenetics in Saccharomyces cerevisiae,
241
Michael Grunstein and Susan M. Gasser
9
Epigenetic Regulation of Chromatin States in
Schizosaccharomyces pombe,
269
Robin C. Allshire and Karl
Ekwall
10
Neurospora
crassa,
a Model System for Epigenetics
Research,
295
Rodolfo
Аттауо
and Eric U. Selker
11
Epigenetics of Gliates,
313
Douglas L. Chalker, Eric Meyer, and
Kazu
f umi
Mochizuki
12
Position-Effect Variegation, Heterochromatin Formation,
and Gene Silencing in
Drosophila,
337
Sarah C.R. Elgin and
Gunter Reuter
13
Epigenetic Regulation in Plants,
363
Craig S. Pikaard and
Ortrun Mittelsten Scheid
Contents
14
The Use or Mouse Models to Study Epigenetics,
395
Mamie Blewitt and Emma Whitclaw
15 DNA Methylation
in Mammals,
423
En Li and Yi Zhang
16
RNAi and Heterochromatin Assembly,
445
Robert
Martiemsen
and Danesh Moazed
17
Transcripti
ona
I Silencing by Polycomb-C
roup
Proteins,
463
Ueli Grossniklaus and
Renato
Paro
18
Transcriptional Regulation by Trithorax-Group
Proteins,
489
Robert E. Kingston and John W. Tamkun
19
Long-Range Chromatin Interactions,
507
job
Dekker
and Tom Misteli
20
Histone Variants and Epigenetics,
529
Steven Henikoffand M. Mitchell Smith
21
Nucleosome Remodeling and Epigenetics,
555
Peter B. Becker and jerry L. Workman
22
Maintenance oi Epigenetic Information,
575
Geneviève Almouzni
and Howard Cedar
23
Regulation of the X Chromosomes in Caenorhabditis
elegans,
599
Susan
Strome,
William G. Kelly, Sevinc Ercan,
and Jason D.
Lieb
24
Dosage Compensation in
Drosophila,
621
John C.
Lucchesi
and Mitzi I. Kuroda
25
Dosage Compensation in Mammals,
641
Neil Brockdorff and Bryan M. Turner
26
Genomic Imprinting in Mammals,
667
Denise
P. Barlow and
Marisa
S.
Bartolomei
V
Germline
and Pluripotent Stem Cells,
687
Wolf
Reik
and M. Azim
Surani
28
Induced Pluripotency and Epigenetic
Reprogramming,
711
Konrad
Hochedlinger and Rudolf Jaenisch
29
Epigenetic Control of Immunity,
737
Mamad
Busslinger
and Alexander Tarakhovsky
30
Metabolic Signaling to Chromatin,
763
Shelley L.
Berger
and Paolo
Sassone-Corsi
31
Epigenetic Regulation in Plant Responses to the
Environment,
787
David C. Baulcombe and Caroline Dean
32
Histone and
DNA
Modifications as Regulators
of
Neuronal
Development and Function,
807
Stavros Lomvardas and Tom Maniatis
33
Epigenetics and Human Disease,
831
Huda
Y
Zoghbi and Arthur I. Beaudet
34
Epigenetic Determinants of Cancer,
859
Stephen B. Baylin and Peter A. Jones
35
Histone Modifications and Cancer,
895
James E.
Audia
and Robert M. Campbell
36
The Necessity of Chromatin: A View
in Perspective,
927
Vincenzo Pirrotta
Appendix
1 :
WWW Resource Pages,
943
Appendix
2:
Comprehensive Catalog of Currently
Documented Histone Modifications,
947
Yinming Zhao and Benjamin A. Garcia
Index,
967
EPIGENETICS
Second Edition
In many biological processes the regulation ot gene expression involves epigenetic mech¬
anisms. In this new edition ot lipi^nctics,
36
chapters written by experts in the
fiolei
introduce and explain epigenetic elleeb
trom
many perspectives.
Illese
include the varied
molecular mechanisms underpinning epigenetic regulation, discussion of cellular pro¬
cesses that rely on this kind of regulation, and surveys ot model organisms in which epi¬
genetic ellects have been most studied.
'Ihe original chapters have all been rewritten and brand new chapters cover topics such as
the structure, function, and dynamics of histone-modifying enzymes and liistone-interact-
ing proteins. Other chapters address
eliminatili
remodeling,
DNA methylation,
siRNAs,
and gene silencing; X-chromosome inactivation, dosage compensation, and imprinting;
and epigenetics in microbes, plants, insects, and mammals.
How epigenetic mechanisms act in cell division and cell type specification, and how er¬
rors in these pathways contribute to cancer and other human diseases are also considered,
along with the importance ot epigenetics for induced pluripotencv and
reprogram
miiig.
In addition, new chapters describe the involvement ot epigenetic processes in epigenetic
inheritance,
neuronal
development, metabolism
ά\κ\
signaling, responses to the environ¬
ment, and long range chroniatin interactions. A scries ot short essays highlight important
recent discoveries.
All the chapters provide1 conceptual
illustrations
ihat
help readers understand epigenetic
control,
lhe
book is thus a benchmark text tor advanced undergraduate and graduate
courses on gene regulation, as well as
лп
essential resource lor scientists interested
m
this
rapidly moving field. |
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| indexdate | 2024-11-25T15:00:53Z |
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| isbn | 9781936113590 |
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| spelling | Epigenetics editors: C. David Allis [und 4 weitere] Second edition Cold Spring Harbor, New York Cold Spring Harbor Laboratory Press [2015] xiv, 984 Seiten Illustrationen txt rdacontent n rdamedia nc rdacarrier Genregulation (DE-588)4122166-7 gnd rswk-swf Epigenese (DE-588)4152503-6 gnd rswk-swf Epigenetik (DE-588)7566079-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Epigenetik (DE-588)7566079-9 s Epigenese (DE-588)4152503-6 s Genregulation (DE-588)4122166-7 s DE-188 Allis, C. David 1951-2023 (DE-588)1051524296 edt Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027302095&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Klappentext Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027302095&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Epigenetics Genregulation (DE-588)4122166-7 gnd Epigenese (DE-588)4152503-6 gnd Epigenetik (DE-588)7566079-9 gnd |
| subject_GND | (DE-588)4122166-7 (DE-588)4152503-6 (DE-588)7566079-9 (DE-588)4143413-4 |
| title | Epigenetics |
| title_auth | Epigenetics |
| title_exact_search | Epigenetics |
| title_full | Epigenetics editors: C. David Allis [und 4 weitere] |
| title_fullStr | Epigenetics editors: C. David Allis [und 4 weitere] |
| title_full_unstemmed | Epigenetics editors: C. David Allis [und 4 weitere] |
| title_short | Epigenetics |
| title_sort | epigenetics |
| topic | Genregulation (DE-588)4122166-7 gnd Epigenese (DE-588)4152503-6 gnd Epigenetik (DE-588)7566079-9 gnd |
| topic_facet | Genregulation Epigenese Epigenetik Aufsatzsammlung |
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